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glutathione-insulin transhydrogenase (32) 32
animals (14) 14
liver - enzymology (9) 9
rats (9) 9
biochemistry & molecular biology (8) 8
humans (8) 8
insulin - metabolism (8) 8
male (7) 7
protein disulfide-isomerases (7) 7
insulin (6) 6
molecular sequence data (6) 6
amino acid sequence (5) 5
glutathione (5) 5
purification (5) 5
cattle (4) 4
degradation (4) 4
kinetics (4) 4
liver (4) 4
protein-disulfide isomerase (4) 4
protein-disulfide reductase (4) 4
thiol (4) 4
bonds (3) 3
chromatography, gel (3) 3
disulfides (3) 3
endoplasmic-reticulum (3) 3
fluorescein-thiocarbamylated insulin (3) 3
hplc (3) 3
human physiology (3) 3
internal medicine (3) 3
isomerases - antagonists & inhibitors (3) 3
isomerases - immunology (3) 3
isomerases - metabolism (3) 3
medicine & public health (3) 3
metabolic diseases (3) 3
multidisciplinary sciences (3) 3
protein disulfide reductase - metabolism (3) 3
rat-liver (3) 3
thioredoxin (3) 3
a and b chains of insulin (2) 2
antibodies (2) 2
antigen-antibody reactions (2) 2
base sequence (2) 2
beta-subunit (2) 2
binding (2) 2
biochemistry (2) 2
biological sciences (2) 2
bovine liver (2) 2
cell line (2) 2
cell membrane - metabolism (2) 2
cho cells (2) 2
dansyl compounds (2) 2
diabetes (2) 2
disulfides - metabolism (2) 2
edetic acid (2) 2
electrophoresis, polyacrylamide gel (2) 2
enzymes (2) 2
ethylmaleimide (2) 2
glycine - analysis (2) 2
insulin - analysis (2) 2
insulin degradation (2) 2
iodine isotopes (2) 2
isomerase (2) 2
isomerases (2) 2
liver microsomal vesicles (2) 2
macromolecular substances (2) 2
membrane (2) 2
microsomes, liver - metabolism (2) 2
monoclonal antibody (2) 2
oxidoreductases (2) 2
oxidoreductases - metabolism (2) 2
peptide hydrolases (2) 2
plasma-membrane (2) 2
prolyl 4-hydroxylase (2) 2
protein disulfide reductase - analysis (2) 2
protein disulfide reductase - isolation & purification (2) 2
protein disulfide-isomerases - metabolism (2) 2
rabbits - immunology (2) 2
radioactive decay (2) 2
rats, inbred strains (2) 2
receptor (2) 2
sulfhydryl compounds - metabolism (2) 2
sulfites (2) 2
インシュリン (2) 2
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肝 (2) 2
酵素 (2) 2
3,3',5-triiodo-l-thyronine (1) 1
4-chloromercuribenzenesulfonate - pharmacology (1) 1
acid (1) 1
adenylate-cyclase (1) 1
aggregation (1) 1
aggregation behaviors (1) 1
alpha-2-macroglobulin (1) 1
alpha-a (1) 1
amino-acid-sequence (1) 1
animal social behavior (1) 1
antibodies, monoclonal - metabolism (1) 1
antibodies, monoclonal - pharmacology (1) 1
antibodies, monoclonal - toxicity (1) 1
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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/1993, Volume 90, Issue 9, pp. 4112 - 4116
Journal Article
Blood, ISSN 0006-4971, 1992, Volume 79, Issue 9, pp. 2226 - 2228
The release of protein disulfide isomerase by activated platelets was hypothesized on the basis of reported intermolecular and intramolecular thiol-disulfide... 
GLUTATHIONE-INSULIN TRANSHYDROGENASE | THIOL | THROMBIN | ISOMERIZATION | COMPLEXES | EXCHANGE | HEMATOLOGY | PLASMA-MEMBRANE | THROMBOSPONDIN | Blood Platelets - enzymology | In Vitro Techniques | Protein Disulfide-Isomerases | Platelet Activation | Isomerases - secretion | Humans
Journal Article
Journal of Veterinary Medical Science, ISSN 0916-7250, 1991, Volume 53, Issue 1, pp. 1 - 4
ラット肝臓中のグルタチオン-インスリン トランスヒドロゲナーゼ (GIT) 活性を, Fluorescein isothiocyanate-Iで標識したインスリンを基質とし, 高速液体クロマトグラフィー (HPLC) を用いてその減少を観察することによって定量する方法を開発した. 標識したインスリンは,... 
glutathione-insulin transhydrogenase | insulin | glutathione | fluorescein-thiocarbamylated insulin | HPLC
Journal Article
Diabetologia, ISSN 0012-186X, 6/1985, Volume 28, Issue 6, pp. 379 - 384
A double-antibody radioimmunoassay for the insulin-degrading enzyme, glutathione-insulin transhydrogenase (GIT), has been developed with the use of rabbit... 
glutathione-insulin transhydrogenase | radioimmunoassay | Medicine & Public Health | Human Physiology | Insulin degradation | Metabolic Diseases | Internal Medicine | human tissues
Journal Article
BBA - Gene Structure and Expression, ISSN 0167-4781, 1988, Volume 949, Issue 2, pp. 169 - 180
A human liver cDNA expression library in λ-phage gt11 was screened with monoclonal antibodies to rat liver protein-disulfide isomerase / oxidoreductase (EC... 
Human | cDNA cloning | Restriction enzyme analysis | Protein-disulfide reductase (glutathione) | Protein-disulfide isomerase | Glutathione-insulin transhydrogenase
Journal Article
BBA - Biomembranes, ISSN 0005-2736, 1983, Volume 732, Issue 1, pp. 170 - 178
Glutathione-insulin transhydrogenase (EC 1.8.4.2) catalyzes the inactivation of insulin through scission of the disulfide bonds to form insulin A and B chains.... 
Rat liver microsome | Glutathione-insulin transhydrogenase | Enzyme topology | Enzyme latency
Journal Article
Journal of Veterinary Medical Science, ISSN 0916-7250, 01/1991, Volume 53, Issue 1, pp. 1 - 4
The activity of rat liver glutathione-insulin transhydrogenase (GIT) was measured. The degradation of fluorescein isothiocyanate-I (FITC-I)-labeled insulin is... 
glutathione-insulin transhydrogenase | insulin
Journal Article
BBA - General Subjects, ISSN 0304-4165, 1987, Volume 923, Issue 3, pp. 389 - 400
Five monoclonal antibodies specific for glutathione-insulin transhydrogenase were characterized. None of the monoclonal antibodies cross-reacted with another... 
Glutathione-insulin transhydrogenase | Thiol:protein disulfide isomerase | Monoclonal antibody
Journal Article
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