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Redox Biology, ISSN 2213-2317, 08/2017, Volume 12, pp. 8 - 17
Synaptic loss and neuron death are the underlying cause of neurodegenerative diseases such as Alzheimer's disease (AD); however, the modalities of cell death... 
Ferroptosis | Neurodegeneration | Alzheimer's disease | Transgenic mice | Cognitive impairment | Glutathione peroxidase 4 | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-DEATH
Journal Article
Development (Cambridge), ISSN 0950-1991, 05/2017, Volume 144, Issue 9, pp. 1687 - 1697
Journal Article
Journal Article
Cell Metabolism, ISSN 1550-4131, 09/2008, Volume 8, Issue 3, pp. 237 - 248
Oxidative stress in conjunction with glutathione depletion has been linked with various acute and chronic degenerative disorders, yet the molecular mechanisms... 
HUMDISEASE | SIGNALING | MOUSE DEVELOPMENT | APOPTOSIS-INDUCING FACTOR | PATHWAY | 12-LIPOXYGENASE | EMBRYONIC STEM-CELLS | ENDOCRINOLOGY & METABOLISM | ATHEROSCLEROSIS | MITOCHONDRIAL DYSFUNCTION | 15-LIPOXYGENASE | HYDROPEROXIDE GLUTATHIONE-PEROXIDASE | NUCLEAR FORM | CELL BIOLOGY | Neurons - pathology | Arachidonate 12-Lipoxygenase - metabolism | Humans | Oxidative Stress - physiology | Apoptosis Inducing Factor - antagonists & inhibitors | Fluorenes - pharmacology | Arachidonate 15-Lipoxygenase - deficiency | Neurons - metabolism | Cell Death - drug effects | Glutathione Peroxidase - deficiency | alpha-Tocopherol - pharmacology | Arachidonate 12-Lipoxygenase - deficiency | Apoptosis Inducing Factor - metabolism | Glutathione Peroxidase - metabolism | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Cells, Cultured | Genotype | Hippocampus - pathology | Arachidonate 15-Lipoxygenase - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Glutathione Peroxidase - genetics | Lipid Peroxidation - physiology | Mice, Knockout | Hippocampus - metabolism | Animals | Cell Death - physiology | Alleles | Mice | Mice, Congenic | Prevention | Oxidative stress | Neurosciences | Thiols | Active oxygen | Cell death | Environmental health | Tocopherols | Development and progression | Biochemistry | Peroxidase
Journal Article
ACS Medicinal Chemistry Letters, ISSN 1948-5875, 09/2017, Volume 8, Issue 9, pp. 963 - 968
A series of benzenesulfonamides bearing selenourea moieties was obtained considering the ureido-sulfonamide SLC-0111, in Phase I clinical trials as antitumor... 
Carbonic anhydrase inhibitors (CAIs) | bioisosterism | selenoureido | metalloenzymes | glutathione peroxidase | CHEMISTRY, MEDICINAL | GLUTATHIONE-PEROXIDASE | DRUG DESIGN | CHEMISTRY | CONVENIENT | CANCER | SELENIUM
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 08/2016, Volume 26, Issue 16, pp. 4086 - 4091
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e50291
Journal Article