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Biological Psychiatry, ISSN 0006-3223, 2008, Volume 63, Issue 1, pp. 6 - 8
In summary, glutamatergic approaches for treatment of schizophrenia were first proposed more than 20 years ago. Nevertheless, compounds for testing these... 
Psychiatry | PHENCYCLIDINE | MODEL | RECEPTORS | NEUROSCIENCES | Schizophrenia - drug therapy | Glycine Plasma Membrane Transport Proteins - physiology | Enzyme Inhibitors - therapeutic use | Humans | Glycine Plasma Membrane Transport Proteins - antagonists & inhibitors
Journal Article
2012, 2012, Handbook of Experimental Pharmacology, ISBN 9783642257575, Volume 213, Issue 213
Book Chapter
Open Medicinal Chemistry Journal, ISSN 1874-1045, 2010, Volume 4, Issue 1, pp. 10 - 19
Multiple lines of evidence indicate that hypofunction of glutamatergic neurotransmission via N-methyl-D-aspartate (NMDA) receptors might be implicated in the... 
Schizophrenia | Glia | Glutamate | Glycine | NMDA receptor | Transporter | Neuroleptics | Mental disorders | Glutamic acid receptors (ionotropic) | sarcosine | N-Methyl-D-aspartic acid receptors | Glial cells | Reviews | Glycine transporter | Glutamatergic transmission | Receptor mechanisms | Neurotransmission | Pharmaceuticals
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 04/2005, Volume 30, Issue 4, pp. 649 - 656
Traditional models of schizophrenia have focused primarily upon dopaminergic (DA) dysregulation. In contrast, more recent models focus on dysfunction of... 
Schizophrenia | Amphetamine | Phencyclidine | Glutamate | NMDA receptor | IN-VIVO MICRODIALYSIS | HIGH-DOSE GLYCINE | TYROSINE-HYDROXYLASE | NEGATIVE SYMPTOMS | PSYCHIATRY | D-ASPARTATE RECEPTORS | amphetamine | schizophrenia | NEUROSCIENCES | RAT NUCLEUS-ACCUMBENS | phencyclidine | GLUTAMATE RECEPTORS | POSITRON-EMISSION-TOMOGRAPHY | PHARMACOLOGY & PHARMACY | MEDIATED RESPONSES | GAMMA-AMINOBUTYRIC-ACID | glutamate | Glycine - metabolism | Schizophrenia - metabolism | Synaptic Transmission - physiology | GABA-B Receptor Antagonists | Receptors, N-Methyl-D-Aspartate - metabolism | Corpus Striatum - metabolism | Receptors, Glycine - antagonists & inhibitors | N-Methylaspartate - pharmacology | Dopamine - secretion | Biphenyl Compounds - pharmacology | Schizophrenia - physiopathology | Synaptic Transmission - drug effects | Sarcosine - analogs & derivatives | Receptors, Glycine - metabolism | Dopamine - metabolism | Organ Culture Techniques | Sarcosine - pharmacology | Receptors, N-Methyl-D-Aspartate - drug effects | Presynaptic Terminals - drug effects | Amino Acid Transport Systems, Neutral - metabolism | Corpus Striatum - secretion | Excitatory Amino Acid Agonists - pharmacology | Glycine Plasma Membrane Transport Proteins | GABA Antagonists - pharmacology | Animals | Corpus Striatum - drug effects | Presynaptic Terminals - metabolism | Mice | Mice, Inbred BALB C | Presynaptic Terminals - secretion | Schizophrenia - drug therapy | Amino Acid Transport Systems, Neutral - antagonists & inhibitors | Receptors, GABA-B - metabolism
Journal Article
Journal Article
European Neuropsychopharmacology, ISSN 0924-977X, 2012, Volume 22, Issue 12, pp. 902 - 910
Abstract Dopaminergic hyperactivity within frontostriatal brain systems is a key feature of schizophrenia, and an objective neural correlate of positive... 
Internal Medicine | Psychiatry | NMDA | Schizophrenia | Striatum | Dopamine | Prefrontal cortex | Glycine transport inhibitor | NEGATIVE SYMPTOMS | PSYCHIATRY | LATENT INHIBITION | D-CYCLOSERINE | PRODROMAL SIGNS | NEUROSCIENCES | CLINICAL NEUROLOGY | PREFRONTAL CORTEX FUNCTION | NMDA RECEPTOR ANTAGONISTS | PHARMACOLOGY & PHARMACY | MEDIATED RESPONSES | FINAL COMMON PATHWAY | METHYL-D-ASPARTATE | WORKING-MEMORY | Glycine Plasma Membrane Transport Proteins - metabolism | Schizophrenia - metabolism | Frontal Lobe - metabolism | Rats | Tetrahydronaphthalenes - therapeutic use | Corpus Striatum - secretion | Male | Treatment Outcome | Corpus Striatum - metabolism | Rats, Sprague-Dawley | Glycine Plasma Membrane Transport Proteins - secretion | Animals | Dopamine - secretion | Tetrahydronaphthalenes - pharmacology | Frontal Lobe - drug effects | Corpus Striatum - drug effects | Frontal Lobe - secretion | Schizophrenia - drug therapy | Glycine Plasma Membrane Transport Proteins - antagonists & inhibitors | Disease Models, Animal | Methyl aspartate | Neurosciences | Analysis | Phenols | Glycine | Brain | Cortex (prefrontal) | Emotional behavior | Mental disorders | Glutamic acid receptors (ionotropic) | Hyperactivity | N-Methyl-D-aspartic acid receptors | Glutamic acid receptors | Cycloserine | Amphetamine | Phencyclidine | Neostriatum | Glutamatergic transmission | Glycine Transport Inhibitor | Prefrontal Cortex
Journal Article
Neuropharmacology, ISSN 0028-3908, 2009, Volume 57, Issue 5, pp. 551 - 555
Journal Article
Psychopharmacology, ISSN 0033-3158, 1/2009, Volume 202, Issue 1, pp. 385 - 396
Journal Article