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Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 05/2002, Volume 90, Issue 10, pp. 1055 - 1063
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2003, Volume 278, Issue 35, pp. 33067 - 33077
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, pp. e0125028 - e0125028
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2001, Volume 276, Issue 1, pp. 251 - 260
The bis-indole indirubin is an active ingredient of Danggui Longhui Wan, a traditional Chinese medicine recipe used in the treatment of chronic diseases such... 
Neostriatum - enzymology | Cyclin-Dependent Kinases - metabolism | Antibiotics, Antineoplastic - pharmacology | Drugs, Chinese Herbal - pharmacology | tau Proteins - metabolism | Glycogen Synthase Kinase 3 | Phosphoproteins - metabolism | Adenosine Triphosphate - pharmacology | CDC2 Protein Kinase - metabolism | Glycogen Synthase Kinases | Antibiotics, Antineoplastic - chemistry | Neostriatum - drug effects | Piperidines - pharmacology | Enzyme Inhibitors - chemistry | Inhibitory Concentration 50 | Indoles - pharmacology | Neostriatum - metabolism | Flavonoids - pharmacology | Molecular Structure | Cyclin-Dependent Kinases - antagonists & inhibitors | Phosphorylation - drug effects | Drugs, Chinese Herbal - therapeutic use | Alkaloids - pharmacology | CDC2 Protein Kinase - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Nerve Tissue Proteins | Alzheimer Disease - enzymology | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Phosphothreonine - metabolism | Cyclin-Dependent Kinase 5 | Dopamine and cAMP-Regulated Phosphoprotein 32 | Animals | Phosphothreonine - analysis | Drugs, Chinese Herbal - chemistry | Alzheimer Disease - metabolism | Cyclin B - metabolism | Mice | Indoles - chemistry | Calcium-Calmodulin-Dependent Protein Kinases - metabolism | Staurosporine - pharmacology | bis-indole indirubin | cdk1 protein | p25 protein | cdk5 protein | Index Medicus
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 1/2005, Volume 168, Issue 1, pp. 29 - 33
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2005, Volume 280, Issue 2, pp. 1457 - 1464
The proglucagon gene (glu) encodes glucagon, expressed in pancreatic islets, and the insulinotropic hormone GLP-1, expressed in the intestines. These two... 
PROMOTER ELEMENT | PROTEIN CDX-2/3 | TRANSCRIPTIONAL ACTIVATION | AMP-RESPONSIVE ELEMENT | GLUCAGON-LIKE PEPTIDE-1 | MOUSE PANCREAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLYCOGEN-SYNTHASE KINASE-3 | LITHIUM-CHLORIDE | 7-36 AMIDE | PANCREATIC-ISLET CELLS
Journal Article
Endocrinology, ISSN 0013-7227, 05/2011, Volume 152, Issue 5, pp. 1755 - 1766
Inhibition of both GSK-3α and GSK-3β in vitro enhances endochondral bone growth, while cartilage-specific deletion of the Gsk3b gene does not affect bone... 
HYPERTROPHIC DIFFERENTIATION | ENDOCHONDRAL BONE-DEVELOPMENT | SMALL-MOLECULE INHIBITORS | ENDOCRINOLOGY & METABOLISM | GROWTH-PLATE | DEVELOPMENTAL REGULATION | REDUCED CHONDROCYTE PROLIFERATION | BETA-CATENIN | CELL-DIFFERENTIATION | WNT/BETA-CATENIN PATHWAY | TRANSCRIPTION FACTOR | Immunohistochemistry | Up-Regulation | Maleimides - pharmacology | Glycogen Synthase Kinase 3 beta | Male | Phosphatidylinositol 3-Kinases - metabolism | Growth Plate - growth & development | Aminophenols - pharmacology | Chondrocytes - drug effects | Gene Deletion | Growth Plate - drug effects | Female | Tibia - growth & development | Chondrocytes - metabolism | Organ Culture Techniques | Tibia - enzymology | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Cartilage - metabolism | Glycogen Synthase Kinase 3 - metabolism | Growth Plate - metabolism | Tibia - drug effects | beta Catenin - metabolism | Blotting, Western | Mice, Knockout | Animals | Glycogen Synthase Kinase 3 - genetics | Cell Proliferation - drug effects | Mice | Cartilage - enzymology | Index Medicus | Abridged Index Medicus | phosphatidylinositides | Wnt protein | catenin | Glycogen synthase kinase 3 | Insulin-like growth factors | Gene deletion | Insulin | Cartilage | Growth plate | Signal transduction | Body height | Bone growth | Tibia | Chondrocytes | Organ culture
Journal Article
Circulation, ISSN 0009-7322, 07/2014, Volume 130, Issue 5, pp. 419 - 430
Journal Article
Nature, ISSN 0028-0836, 07/2000, Volume 406, Issue 6791, pp. 86 - 90
Glycogen synthase kinase-3 (GSK-3)-α and -β are closely related protein-serine kinases, which act as inhibitory components of Wnt signalling during embryonic... 
INHIBITION | LETHALITY | INDUCED APOPTOSIS | 3-KINASE | MULTIDISCIPLINARY SCIENCES | KINASE | XENOPUS EMBRYOS | DEATH | MICE | AKT | LITHIUM | glycogen synthase kinase-3^b | NF-^KB protein | GSK-3^b gene
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2003, Volume 100, Issue 11, pp. 6370 - 6375
acquires toxicity by self-aggregation. To identify and characterize the toxic form(s) of Aβ aggregates, we examined in vitro aggregation conditions by using... 
Oligomers | Aggregation | Atomic force microscopy | Biological Sciences | Transmission electron microscopy | Neurons | Cell death | Cell aggregates | Lithium | Solar fibrils | Functional groups | FIBRIL FORMATION | ATOMIC-FORCE MICROSCOPY | PEPTIDES | THERAPY | MECHANISM | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | NEURONS | LITHIUM | OLIGOMERS | BRAIN | Tau protein kinase | glycogen synthase kinase 3^b
Journal Article