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Clinical science (1979), ISSN 1470-8736, 2012, Volume 122, Issue 10, pp. 473 - 483
.... A total of seven 9-month-old Type 2 diabetic Goto–Kakizaki rats were treated peripherally for 4 weeks with Ex-4 at 0.1, 1 or 5 μ... 
Neuroprotection | Exendin-4 (Ex-4) | Goto-Kakizaki (GK) rat | Neurogenesis | Middle cerebral artery occlusion (MCAO) | MEDICINE, RESEARCH & EXPERIMENTAL | middle cerebral artery occlusion (MCAO) | RISK-FACTORS | ADULT BRAIN | TOTAL NUMBER | DOPAMINERGIC-NEURONS | SUBVENTRICULAR ZONE | EXENDIN-4 | exendin-4 (Ex-4) | neuroprotection | neurogenesis | ANIMAL-MODEL | CEREBRAL-ISCHEMIA | HIPPOCAMPAL NEUROGENESIS | PARKINSONS-DISEASE | Neuroprotective Agents - therapeutic use | Receptors, Glucagon - agonists | Microglia - drug effects | Rats | Stroke Volume - drug effects | Male | Stroke - drug therapy | Hyperglycemia - drug therapy | Animals | Glucagon-Like Peptide-1 Receptor | Brain Ischemia - drug therapy | Brain Ischemia - pathology | Venoms - therapeutic use | Cell Proliferation - drug effects | Neurogenesis - drug effects | Diabetes Mellitus, Type 2 - drug therapy | Drug Evaluation, Preclinical | Diabetes Mellitus, Type 2 - complications | Peptides - therapeutic use | Index Medicus | S4 | T2D, Type 2 diabetes | BrdU, bromodeoxyuridine | S7 | MCAO, MCA occlusion | DAPI, 4′,6-diamidino-2-phenylindole | DCX, doublecortin | GK, Goto–Kakizaki | Goto–Kakizaki (GK) rat | CNS, central nervous system | MCA, middle cerebral artery | IHC, immunohistochemistry | Ex-4, exendin-4 | bw, body weight | GLP-1R, glucagon-like peptide-1 receptor | SVZ, subventricular zone
Journal Article
Biochemical journal, ISSN 1470-8728, 2004, Volume 381, Issue 1, pp. 13 - 18
...-cells, from normal and diabetic Goto–Kakizaki (GK) rats, using total internal reflection fluorescence microscopy (TIRFM... 
Membrane fusion | Insulin release | Pancreatic β-cell | Exocytosis | Total internal reflection fluorescence microscopy (TIRFM) | Diabetes mellitus | EVANESCENT-WAVE MICROSCOPY | total internal reflection fluorescence microscopy (TIRFM) | ISLETS | BIOCHEMISTRY & MOLECULAR BIOLOGY | diabetes mellitus | MELLITUS | FACTOR ATTACHMENT PROTEIN | membrane fusion | insulin release | GREEN FLUORESCENT PROTEIN | pancreatic beta-cell | GK RATS | GLUCOSE-METABOLISM | exocytosis | EXPRESSION | SECRETORY GRANULES | Immunohistochemistry | Recombinant Proteins - metabolism | Green Fluorescent Proteins | Membrane Fusion | Rats, Wistar | Secretory Vesicles - chemistry | Insulin - immunology | Secretory Vesicles - metabolism | Islets of Langerhans - chemistry | Rats | Male | Image Processing, Computer-Assisted - methods | Exocytosis - physiology | Insulin - metabolism | Animals | Microscopy, Fluorescence - methods | Islets of Langerhans - metabolism | Rats, Mutant Strains | Islets of Langerhans - cytology | Diabetes Mellitus, Experimental - metabolism | Insulin Secretion | Luminescent Proteins - metabolism | GFP, green fluorescent protein | FBS, fetal bovine serum | pancreatic β-cell | Accelerated Publication | KRB, Krebs–Ringer buffer | GK, Goto–Kakizaki | RRP, readily-releasable pool | eGFP, enhanced GFP | TIRF, total internal reflection fluorescence | TIRFM, TIRF microscopy
Journal Article
Journal Article
British journal of pharmacology, ISSN 1476-5381, 08/2009, Volume 157, Issue 8, pp. 1549 - 1556
... glucose levels and prevent diabetic complications in an experimental model of type 2 diabetes in Goto-Kakizaki (GK) rats... 
glucose | Goto-Kakizaki rat | pain sensitivity | myocardial infarction | mildronate | L-carnitine | diabetes | L‐carnitine | Goto‐Kakizaki rat | Myocardial infarction | Pain sensitivity | Diabetes | Glucose | Mildronate | ACID | STIMULATION | HEART-FAILURE | DEFICIENCY | SKELETAL-MUSCLE | GK RAT | CARNITINE BIOSYNTHESIS | PHARMACOLOGY & PHARMACY | DYSFUNCTION | ENERGY-METABOLISM | INHIBITOR | Diabetes Mellitus, Experimental - drug therapy | Rats, Wistar | Male | Carnitine - metabolism | Diabetes Mellitus, Type 2 - metabolism | Fructosamine - metabolism | Lipids - blood | Methylhydrazines - therapeutic use | Myocardial Ischemia - physiopathology | Diabetes Mellitus, Experimental - metabolism | Diabetes Mellitus, Experimental - physiopathology | Disease Models, Animal | Heart - physiopathology | Hypoglycemic Agents - therapeutic use | Administration, Oral | Hyperalgesia - prevention & control | Myocardial Ischemia - prevention & control | Rats | Cardiovascular Agents - pharmacology | Hyperalgesia - physiopathology | Hypoglycemic Agents - pharmacology | Cardiovascular Agents - therapeutic use | Animals | Diabetes Mellitus, Type 2 - physiopathology | 3-Hydroxybutyric Acid - metabolism | Methylhydrazines - pharmacology | Heart - drug effects | Pain Threshold | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | In Vitro Techniques | Research Papers
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 04/2011, Volume 300, Issue 4, pp. 1174 - 1181
Journal Article
Nutrition Research, ISSN 0271-5317, 2014, Volume 34, Issue 2, pp. 160 - 167
Journal Article
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e55925
.... Here in present work, we have extended this approach using diabetic Goto-kakizaki (GK) rats. We administered... 
IN-VITRO RELEASE | HIGH-FAT | GOTO-KAKIZAKI RAT | ISLET-ASSOCIATED MACROPHAGES | INTERLEUKIN-1 RECEPTOR ANTAGONIST | INSULIN-RESISTANCE | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | BETA-CELL | MODEL | TYPE-2 | Interleukin 1 Receptor Antagonist Protein - administration & dosage | Kidney - pathology | Skin - metabolism | Male | Insulin - blood | Hyperglycemia - drug therapy | Antigens, CD - metabolism | Kidney Function Tests | Kidney - metabolism | Islets of Langerhans - metabolism | Diabetes Mellitus, Type 2 - complications | Skin - pathology | Disease Models, Animal | Hyperglycemia - prevention & control | Glucose Tolerance Test | Kidney - drug effects | Gels | Insulin Resistance | Rats | Diabetes Mellitus, Type 2 - blood | Animals | Hyperglycemia - blood | Antigens, Differentiation, Myelomonocytic - metabolism | Poloxamer | Interleukin 1 Receptor Antagonist Protein - adverse effects | Hyperglycemia - etiology | Diabetes Mellitus, Type 2 - drug therapy | Type 2 diabetes | Hyperglycemia | Blood sugar monitoring | Interleukins | Physiological aspects | Skin | Glucose | Glucose tolerance tests | Dextrose | Drugs | Syngeneic grafts | Pathogenesis | Weaning | Interleukin | Drug delivery | Interleukin 1 receptors | Macrophages | Interleukin 6 | Toxicology | Rodents | Interleukin 1 | Histochemical analysis | Pancreas | Pharmaceutical sciences | Half life | Urine | Kidneys | Cytokines | Interleukin 1 receptor antagonist | Diabetes mellitus | Body temperature | Inflammation | Pharmacology | FDA approval | Metabolism | Insulin | Studies | Glucose tolerance | Insulin resistance | Infiltration | Diabetes | Chemokines | Apoptosis
Journal Article