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1. Full Text Comparing of endocyclic and exocyclic cleavage reactions using mycothiol synthesis as an example
by Manabe, Shino and Ito, Yukishige
Tetrahedron, ISSN 0040-4020, 05/2018, Volume 74, Issue 20, pp. 2440 - 2446
Glycosides can be cleaved in either an exo- or endocyclic fashion. Specifically, the former pathway is used during conventional glycosylation; whereas the... 
Glycosides | Glycosylation | Mycothiol | Anomerization | Cyclitols | ALPHA-GLYCOSYLATION | GPI ANCHOR | CHEMISTRY, ORGANIC | OLIGOSACCHARIDE | INOSITOL | THIOLS | PHOSPHATIDYLINOSITOL DIMANNOSIDE | BIOSYNTHESIS
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2. Full Text Expanding the phenotypic spectrum of Mabry Syndrome with novel PIGO gene variants associated with hyperphosphatasia, intractable epilepsy, and complex gastrointestinal and urogenital malformations
by Holtz, Alexander M and Harrington, Amanda W and McNamara, Erin R and Kielian, Agnieszka and Soul, Janet S and Martinez-Ojeda, Mayra and Levy, Philip T
European Journal of Medical Genetics, ISSN 1769-7212, 11/2019, p. 103802
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3. Full Text Understanding human glycosylation disorders: Biochemistry leads the charge
by Freeze, Hudson H
Journal of Biological Chemistry, ISSN 0021-9258, 03/2013, Volume 288, Issue 10, pp. 6936 - 6945
Nearly 70 inherited human glycosylation disorders span a breathtaking clinical spectrum, impacting nearly every organ system and launching a family-driven... 
PHOSPHOMANNOSE ISOMERASE DEFICIENCY | PHOSPHATE-MANNOSE SYNTHASE | GENE | ZEBRAFISH MODEL | BIOCHEMISTRY & MOLECULAR BIOLOGY | O-MANNOSYLATION | CONGENITAL DISORDERS | HYPERPHOSPHATASIA | DOLICHOL | MUTATIONS | GLYCOSYLPHOSPHATIDYLINOSITOL | Hypoglycemia - genetics | Genetic Predisposition to Disease - genetics | Humans | Liver - metabolism | Congenital Disorders of Glycosylation - metabolism | Mannosyltransferases - genetics | Exome - genetics | Glycosylphosphatidylinositols - metabolism | Liver - abnormalities | Mutation | Sequence Analysis, DNA - methods | Congenital Disorders of Glycosylation - genetics | Congenital Disorders of Glycosylation - diagnosis | GPI Anchor | Dystroglycanopathy | Glycobiology | Glycosylation Inhibitors | Congenital Disorders of Glycosylation | Glycosyltransferases | Minireviews | Glycosylation | Golgi | N-Glycosylation | Whole Exome Sequencing
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4. Full Text Membrane-type matrix metalloproteinases: Their functions and regulations
by Itoh, Yoshifumi
Matrix Biology, ISSN 0945-053X, 05/2015, Volume 44-46, pp. 207 - 223
Membrane-type matrix metalloproteinases (MT-MMPs) form a subgroup of the matrix metalloproteinase (MMP) family, and there are 6 MT-MMPs in humans. MT-MMPs are... 
MT-MMP | GPI-anchor | MMP | ECM degradation | Transmembrane | CANCER-CELLS | 1-MATRIX METALLOPROTEINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 3-DIMENSIONAL EXTRACELLULAR-MATRIX | HEMOPEXIN-LIKE DOMAIN | GELATINASE-A MMP-2 | RENAL-CELL CARCINOMA | CELL BIOLOGY | HUMAN BREAST-CARCINOMA | TISSUE INHIBITOR | TUMOR-GROWTH | ENDOTHELIAL GROWTH-FACTOR | Gene Expression Regulation, Enzymologic | Cell Membrane - enzymology | Matrix Metalloproteinases, Membrane-Associated - chemistry | Animals | Humans | Neoplasms - enzymology | Matrix Metalloproteinases, Membrane-Associated - metabolism | Arthritis - enzymology | Enzymes | Laws, regulations and rules
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5. Full Text Synthesis of analogs of the Gwt1 inhibitor manogepix (APX001A) and in vitro evaluation against Cryptococcus spp
by Trzoss, Michael and Covel, Jonathan A and Kapoor, Mili and Moloney, Molly K and Soltow, Quinlyn A and Webb, Peter J and Shaw, Karen Joy
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 12/2019, Volume 29, Issue 23, p. 126713
Fosmanogepix (APX001) is a first-in-class prodrug molecule that is currently in Phase 2 clinical trials for invasive fungal infections. The active moiety... 
Fosmanogepix | APX001 | Antifungal | Manogepix | Cryptococcus | APX001A | GPI anchor biosynthesis | Gwt1 | MGX | CHEMISTRY, MEDICINAL | E1210 | CHEMISTRY, ORGANIC | MENINGITIS | DISEASE | BURDEN
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6. Full Text An efficient synthesis of a 6″-BODIPY-α-Galactosylceramide probe for monitoring α-Galactosylceramide uptake by cells
by Cheng, Janice M.H and Chee, Stephanie H and Dölen, Yusuf and Verdoes, Martijn and Timmer, Mattie S.M and Stocker, Bridget L
Carbohydrate Research, ISSN 0008-6215, 12/2019, Volume 486, p. 107840
Herein, an efficient synthesis of BODIPY-α-Galactosylceramide , which can be used to study the cellular uptake of the potent immunostimulatory parent compound... 
GALCER ANALOGS | RECOGNITION | KRN7000 | GPI-ANCHOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE | CHEMISTRY, ORGANIC | ANTIGEN PRESENTATION | CD1D | BIOLOGICAL EVALUATION | CHEMISTRY | CHEMISTRY, APPLIED | RESIDUES
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7. Full Text Fungal Cell Wall Organization and Biosynthesis
by Free, Stephen J
2013, Advances in Genetics, ISBN 0124076777, Volume 81, 50
The composition and organization of the cell walls from , , , , , and are compared and contrasted. These cell walls contain chitin, chitosan, β-1,3-glucan,... 
Glucan | Candida albicans | Cryptococcus neoformans | Fungal cell wall | Schizosaccharomyces pombe | Chitin | Neurospora crassa | Aspergillus fumigatus | Cell wall biogenesis | Saccharomyces cerevisiae | GLYCOSYLPHOSPHATIDYLINOSITOL GPI ANCHOR | CONIDIAL PIGMENT BIOSYNTHESIS | ASPERGILLUS-FUMIGATUS | CANDIDA-ALBICANS | CHITIN SYNTHASE ACTIVITY | GENETICS & HEREDITY | PATHOGEN CRYPTOCOCCUS-NEOFORMANS | SACCHAROMYCES-CEREVISIAE | NEUROSPORA-CRASSA | SCHIZOSACCHAROMYCES-POMBE | BIOFILM FORMATION | Glycoproteins - biosynthesis | Glucans - biosynthesis | Cell Wall - metabolism | Fungi - cytology | Cell Wall - chemistry | Fungi - metabolism | Yeasts - cytology | Yeasts - metabolism
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8. Full Text CD24 induces localization of β1 integrin to lipid raft domains
by Runz, Steffen and Mierke, Claudia T and Joumaa, Safwan and Behrens, JĂĽrgen and Fabry, Ben and Altevogt, Peter
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 2008, Volume 365, Issue 1, pp. 35 - 41
The expression of the glycosyl phosphatidylinositol (GPI)-anchored protein CD24 correlates with poor prognosis in a variety of carcinomas. However, little is... 
GPI-anchor | Transmigration | Motility | Cell invasion | Membrane rafts | Lipid rafts | CD24 | Invasion | Integrins
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9. Full Text Arabinogalactan-proteins and the research challenges for these enigmatic plant cell surface proteoglycans
by Tan, Li and Showalter, Allan M and Egelund, Jack and Hernandez-Sanchez, Arianna and Doblin, Monika S and Bacic, Antony
Frontiers in Plant Science, ISSN 1664-462X, 06/2012, Volume 3, p. 140
Arabinogalactan-proteins (AGPs) are complex glycoconjugates that are commonly found at the cell surface and in secretions of plants. Their location and... 
Glycosylphosphatidylinositol anchor | Galactosyltransferase | Arabinogalactan-proteins | AGP polysaccharide complexes | Cell surface signaling | Fasciclin-like AGP | glycosylphosphatidylinositol anchor | cell surface signaling | galactosyltransferase | fasciclin-like AGP | arabinogalactan-proteins | PLANT SCIENCES | Arabinogalactan-proteins (AGPs) | fasciclin-like AGP (FLA) | galactosyltransferase (GalT) | glycosylphosphatidylinositol (GPI) anchor | AGP polysaccharide complexes (APCs) | cell surface signalling
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10. Full Text Structure and function of legumain in health and disease
by Dall, Elfriede and Brandstetter, Hans
Biochimie, ISSN 0300-9084, 03/2016, Volume 122, pp. 126 - 150
The last years have seen a steady increase in our understanding of legumain biology that is driven from two largely uncoupled research arenas, the mammalian... 
Caspase | Allostery | Electrostatic stabilization | Cellular localization | Context-dependent activities | Death domain | SCHISTOSOMA-MANSONI | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | AZA-PEPTIDE EPOXIDES | ANTIGEN PRESENTATION | VACUOLAR PROCESSING ENZYME | ACTIVITY-BASED PROBES | GPI ANCHOR ATTACHMENT | ASPARAGINYL ENDOPEPTIDASE LEGUMAIN | TUMOR-ASSOCIATED MACROPHAGES | CYSTEINE PROTEINASE-INHIBITOR | Cysteine Endopeptidases - chemistry | Cytoplasm - enzymology | Humans | Lysosomes - enzymology | Models, Molecular | Neoplasms - enzymology | Neoplasms - diagnosis | Alzheimer Disease - enzymology | Cell Nucleus - enzymology | Alzheimer Disease - diagnosis | Cysteine Endopeptidases - metabolism | Peptides - metabolism | Protein Conformation | Physiological aspects | Ligases | Cysteine
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11. Full Text GDE2/GDPD5 in neuroblastoma
by Matas-Rico, Elisa and van Veen, Michiel and Moolenaar, Wouter H
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 4, pp. 5672 - 5673
Proteoglycan | Glycerophosphodiesterase | Biomarker | Neuroscience | Differentiation | GPIanchor | GPI-anchor | differentiation | glycerophosphodiesterase | biomarker | proteoglycan | CELL BIOLOGY
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12. Full Text APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Coccidioides immitis Pneumonia
by Viriyakosol, Suganya and Kapoor, Mili and Okamoto, Sharon and Covel, Jonathan and Soltow, Quinlyn A and Trzoss, Michael and Shaw, Karen Joy and Fierer, Joshua
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 02/2019, Volume 63, Issue 2
Coccidioidomycosis is a systemic fungal infection caused by the inhalation of the arthroconidia of either of two closely related dimorphic fungi, Coccidioides... 
Antifungal therapy | APX001 | 1-aminobenzotriazole | Coccidioides | APX001A | GPI anchor biosynthesis | Gwt1 | CLSI | antifungal therapy | E1210 | CANDIDIASIS | MICROBIOLOGY | BROAD-SPECTRUM ANTIFUNGAL | FUSARIUM | ASPERGILLUS | MODELS | PHARMACOLOGY & PHARMACY | FLUCONAZOLE
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13. Full Text Mutations in PIGY: Expanding the phenotype of inherited glycosylphosphatidylinositol deficiencies
by Ilkovski, Biljana and Pagnamenta, Alistair T and O'Grady, Gina L and Kinoshita, Taroh and Howard, Malcolm F and Lek, Monkol and Thomas, Brett and Turner, Anne and Christodoulou, John and Sillence, David and Knight, Samantha J.L and Popitsch, Niko and Keays, David A and Anzilotti, Consuelo and Goriely, Anne and Waddel, Leigh B and Brilot, Fabienne and North, Kathryn N and Kanzawa, Noriyuki and Macarthur, Daniel G and Taylor, Jenny C and Kini, Usha and Murakami, Yoshiko and Clarke, Nigel F
Human Molecular Genetics, ISSN 0964-6906, 2015, Volume 24, Issue 21, pp. 6146 - 6159
Glycosylphosphatidylinositol (GPI)-anchored proteins are ubiquitously expressed in the human body and are important for various functions at the cell surface.... 
GPI ANCHOR DEFICIENCY | GENE | MENTAL-RETARDATION SYNDROME | BIOSYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | HYPERPHOSPHATASIA | PAROXYSMAL-NOCTURNAL HEMOGLOBINURIA | EPILEPSY | PROMOTER | GENOME | Gene Expression | Membrane Proteins - genetics | Glycosylphosphatidylinositols - genetics | Humans | Child, Preschool | Infant | Male | CD55 Antigens - biosynthesis | CD59 Antigens - biosynthesis | Phenotype | Transfection | DNA Mutational Analysis | Cell Line, Tumor | Female | Mutation | Glycosylphosphatidylinositols - deficiency | Infant, Newborn
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14. Full Text Interrogation of Milk-Driven Changes to the Proteome of Intestinal Epithelial Cells by Integrated Proteomics and Glycomics
by Morrin, Sinead T and Owens, Rebecca A and Le Berre, Marie and Gerlach, Jared Q and Joshi, Lokesh and Bode, Lars and Irwin, Jane A and Hickey, Rita M
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 02/2019, Volume 67, Issue 7, pp. 1902 - 1917
Bovine colostrum is a rich source of bioactive components which are important in the development of the intestine, in stimulating gut structure and function... 
milk | receptor | glycomics | lectin array | bovine colostrum | proteome | GPI-ANCHOR | FOOD SCIENCE & TECHNOLOGY | COLON | GLYCOSYLATION | BIFIDOBACTERIUM-BIFIDUM | AGRICULTURE, MULTIDISCIPLINARY | GENE-EXPRESSION | EXTRACELLULAR-MATRIX DEGRADATION | CHEMISTRY, APPLIED | PROTEINS | BINDING | INNATE IMMUNITY | CATHEPSIN-B
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15. Full Text Cellular consequences of diminished protein O-mannosyltransferase activity in baker’s yeast
by Zatorska, Ewa and Gal, Lihi and Schmitt, Jaro and Bausewein, Daniela and Schuldiner, Maya and Strahl, Sabine
International Journal of Molecular Sciences, ISSN 1661-6596, 06/2017, Volume 18, Issue 6, p. 1226
O-Mannosylation is a type of protein glycosylation initiated in the endoplasmic reticulum (ER) by the protein O-mannosyltransferase (PMT) family. Despite the... 
GPI anchor | Mannosyltransferase | Calcineurin | Glycosylation | Endoplasmic reticulum | Oligosaccharyltransferase | Cell wall | Unfolded protein response | unfolded protein response | oligosaccharyltransferase | mannosyltransferase | glycosylation | cell wall | calcineurin | endoplasmic reticulum
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16. Full Text Glycosylphosphatidylinositol-anchored proteins: Membrane organization and transport
by Zurzolo, Chiara and Simons, Kai
BBA - Biomembranes, ISSN 0005-2736, 04/2016, Volume 1858, Issue 4, pp. 632 - 639
Glycosylphosphatidylinositol (GPI)-anchored proteins (GPI-APs) are a class of membrane proteins containing a soluble protein attached by a conserved glycolipid... 
Cholesterol-dependent domains | Oligomerization | Lipid–protein interaction | Apical sorting | GPI-anchored proteins | Nanoclusters | Lipid-protein interaction | MDCK CELLS | CANINE KIDNEY-CELLS | GPI-ANCHOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | N-GLYCANS | PLASMA-MEMBRANE | BASOLATERAL MEMBRANE | SECRETORY PATHWAY | RECYCLING ENDOSOMES | BIOPHYSICS | POLARIZED EPITHELIAL-CELLS | APICAL MEMBRANE | Membrane proteins
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