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gpr109a (130) 130
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Annals of Clinical and Laboratory Science, ISSN 0091-7370, 11/2017, Volume 47, Issue 6, pp. 729 - 737
Journal Article
Cell metabolism, ISSN 1550-4131, 9/2018, Volume 28, Issue 3, pp. 432 - 448.e4
Pathogen burden accelerate atherosclerosis, but the mechanisms remain unresolved. Activation of the NLRP3 inflammasome is linked to atherogenesis. Here we... 
atherosclerosis | foam cells | ABCA1 | C. pneumoniae | Gpr109a | oxLDL | niacin | macrophage | Nlrp3 | cholesterol efflux | aspartate | Interleukin-1 beta
Journal Article
Journal of Neuroimmunology, ISSN 0165-5728, 07/2018, Volume 320, pp. 76 - 79
Neuroinflammation remains a central piece in Parkinson's disease (PD) pathophysiology. However, mechanisms by which PD links to the neuroinflammation remain... 
GPR109A | Parkinson's disease | Macrophage polarization | Niacin | ACTIVATION | IMMUNOLOGY | RECEPTORS | NEUROSCIENCES | Medical colleges | Inflammation | Macrophages
Journal Article
Journal Article
Bioorganic and Medicinal Chemistry, ISSN 0968-0896, 06/2015, Volume 23, Issue 14, pp. 4013 - 4025
Structure-affinity relationship (SAR) and structure-kinetics relationship (SKR) studies were combined to investigate a series of biphenyl anthranilic acid... 
GPR109A/HCA 2 receptor | Residence time | Nicotinic acid | Biphenyl anthranilic acid derivatives | Kinetics
Journal Article
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 03/2019, Volume 1865, Issue 3, pp. 688 - 695
Inflammation and cellular energetics play critical roles in organ dysfunction following hemorrhagic shock. Recent studies suggest a putative role for sirtuin 1... 
Immunometabolism | Trauma | Hemorrhage | Nicotinic acid | HOMEOSTASIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GPR109A | INJURY | SIRT1 | RAT MODEL | NICOTINIC-ACID | ADHESION | BIOPHYSICS | GENES | MITOCHONDRIAL DYSFUNCTION | RESUSCITATION
Journal Article
EBioMedicine, ISSN 2352-3964, 04/2018, Volume 30, pp. 317 - 325
G Protein Coupled Receptor 109A (GPR109A), which belongs to the G protein coupled receptor family, can be activated by niacin, butyrate, and β-hydroxybutyric... 
GPR109A | IBD | Inflammation | Epithelium barrier | TNBS | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | IMPROVES INSULIN SENSITIVITY | GUT | RECEPTOR | KAPPA-B | NICOTINIC-ACID | MOLECULAR-IDENTIFICATION | CHAIN FATTY-ACIDS | DIETARY FIBER | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2014, Volume 124, Issue 5, pp. 2188 - 2192
Journal Article
Scientific Reports, ISSN 2045-2322, 11/2015, Volume 5, Issue 1, pp. 16148 - 16148
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 06/2019, Volume 33, Issue 6, pp. 7625 - 7634
Sepsis is characterized by systemic inflammation that is caused by infection and by activation of proinflammatory pathways, resulting in mitochondrial and... 
acute kidney injury (AKI) | CLP | PUMA-G | BIOCHEMISTRY & MOLECULAR BIOLOGY | GPR109A | RECEPTOR | NORMAL SALINE | RINGERS SOLUTION | CELL BIOLOGY | NICOTINIC-ACID | SYSTEMIC INFLAMMATION | PGC1 alpha | macrophages | MOLECULAR-IDENTIFICATION | pro-inflammatory cytokines | KIDNEY INJURY | BIOLOGY
Journal Article
Cellular and Molecular Immunology, ISSN 1672-7681, 02/2018, Volume 15, Issue 2, pp. 88 - 91
Journal Article
International Journal of Pharmaceutical Sciences Review and Research, ISSN 0976-044X, 09/2016, Volume 40, Issue 1, pp. 313 - 317
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 09/2015, Volume 56, Issue 9, pp. 1679 - 1690
Acute nicotinic acid (NiAc) administration results in rapid reduction of plasma FFA concentrations. However, sustained NiAc exposure is associated with... 
s | drug therapy | insulin | tachyphylaxis | adipose tissue | niacin | GPR109A | lipolysis and fatty acid metabolism | diabetes | hypolipidemic drugs
Journal Article
Current Pharmaceutical Biotechnology, ISSN 1389-2010, 10/2015, Volume 16, Issue 1, pp. 3 - 10
Nicotinic acid (NA) decreases low density lipoprotein (LDL) cholesterol and increases highdensity lipoprotein (HDL) cholesterol at pharmacological doses... 
Glucose metabolism | Receptor GPR109A | Regulatory mechanism | Nicotinic acid | Nicotinamide | Adipokine | Lipid metabolism
Journal Article
by Yang, RL and He, JY and Wang, YL
EUROPEAN JOURNAL OF PHARMACOLOGY, ISSN 0014-2999, 11/2016, Volume 791, pp. 124 - 136
After spinal cord injury (SCI), there is an acute phase of alternatively activated (M2) macrophage infiltration, followed by a long-lasting phase of... 
OXIDATIVE STRESS | M2 MACROPHAGES | HCA receptor | PUMA-G | REGENERATION | GPR109A | Inflammation | KAPPA-B | Spinal cord injury | Macrophages | Niacin | MACROPHAGE ACTIVATION | NICOTINIC-ACID | LOCOMOTOR RECOVERY | PHARMACOLOGY & PHARMACY
Journal Article
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