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Current Genomics, ISSN 1389-2029, 11/2010, Volume 11, Issue 7, pp. 537 - 561
Journal Article
Science, ISSN 0036-8075, 09/2014, Volume 345, Issue 6201, pp. 1139 - 1145
Many RNA regulatory proteins controlling pre-messenger RNA splicing contain serine: arginine (SR) repeats. Here, we found that these SR domains bound hydrogel... 
INTRANUCLEAR DISTRIBUTION | MULTIDISCIPLINARY SCIENCES | EXPANSION | SEQUENCE | ALS | HEXANUCLEOTIDE REPEAT | GRANULES | PROTEIN-KINASES | FOCI | SR SPLICING FACTORS | DEGENERATION | Phosphorylation | Protein Biosynthesis | Alternative Splicing | Protein-Tyrosine Kinases - metabolism | Humans | Astrocytes - pathology | Glutamate Plasma Membrane Transport Proteins - genetics | Frontotemporal Dementia - metabolism | RNA, Messenger - biosynthesis | Repetitive Sequences, Amino Acid | Hydrogel, Polyethylene Glycol Dimethacrylate | Cell Nucleolus - metabolism | RNA, Messenger - antagonists & inhibitors | Cell Death | Transcription, Genetic | C9orf72 Protein | Dipeptides - metabolism | Protein-Serine-Threonine Kinases - metabolism | Frontotemporal Dementia - pathology | Frontotemporal Dementia - genetics | Protein Structure, Tertiary | Amyotrophic Lateral Sclerosis - genetics | Dipeptides - pharmacology | Cells, Cultured | Heterogeneous-Nuclear Ribonucleoprotein Group A-B - metabolism | RNA, Ribosomal - antagonists & inhibitors | RNA, Antisense - biosynthesis | Proteins - genetics | Amyotrophic Lateral Sclerosis - pathology | RNA, Antisense - antagonists & inhibitors | Amyotrophic Lateral Sclerosis - metabolism | RNA, Ribosomal - biosynthesis | Dipeptides - genetics | Astrocytes - metabolism | Cell death | Ribonucleoproteins | Genetic research | Genetic aspects | Research | Properties | RNA splicing | Proteins | Amyotrophic lateral sclerosis | Biosynthesis | Polypeptides | Ribonucleic acid--RNA | Apoptosis | Index Medicus | Neurological diseases | Ribonucleic acids | Peptides | Toxicity | Genes | Drosophila | Genetics
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/2015, Volume 34, Issue 21, pp. 2633 - 2651
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 02/2012, Volume 52, Issue 3, pp. 646 - 659
Recent findings suggest that endoplasmic reticulum stress may be involved in the pathogenesis of domoic acid-induced neurodegeneration. Purple sweet potato... 
ERα-mediated mitochondrial biogenesis signaling | Free radicals | Purple sweet potato color | Domoic acid | Cognitive deficits | Endoplasmic reticulum stress | CEREBELLAR GRANULE NEURONS | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | KAINIC ACID | INDUCTION | ER alpha-mediated mitochondrial biogenesis signaling | PATHWAY | ENDOCRINOLOGY & METABOLISM | INDUCED NEUROTOXICITY | EXPRESSION | BRAIN | Neuroprotective Agents - therapeutic use | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Oxidative Stress | Plant Extracts - pharmacology | Cognition Disorders - chemically induced | Kainic Acid - analogs & derivatives | NADPH Oxidases - metabolism | Neurodegenerative Diseases - prevention & control | Male | Hippocampus - drug effects | Cognition Disorders - prevention & control | Neuroprotective Agents - pharmacology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Nuclear Respiratory Factor 1 - metabolism | Trans-Activators - genetics | NADPH Oxidases - genetics | Anthocyanins - therapeutic use | Estrogen Receptor alpha - metabolism | Hippocampus - enzymology | Ipomoea batatas - chemistry | Superoxide Dismutase - metabolism | Anthocyanins - pharmacology | Endoplasmic Reticulum Stress - drug effects | Signal Transduction | Catalase - genetics | Hippocampus - pathology | Mitochondria - metabolism | Maze Learning - drug effects | Mice, Inbred ICR | Catalase - metabolism | Up-Regulation - drug effects | Hippocampus - metabolism | Animals | Estrogen Receptor alpha - genetics | Neurodegenerative Diseases - chemically induced | Trans-Activators - metabolism | Mice | Transcription Factors | Superoxide Dismutase-1 | Plant Extracts - therapeutic use | Apoptosis | Brain | Neuroprotection | Reactive oxygen species | RNA | Cognitive ability | Color | Oral administration | Estrogen receptors | estrogenic activity | Stress | Signal transduction | Mitochondria | Neurodegeneration | Excitotoxicity | Anthocyanins | Endoplasmic reticulum | Hippocampus | Index Medicus
Journal Article
Current Biology, ISSN 0960-9822, 07/2019, Volume 29, Issue 14, pp. 2339 - 2350.e5
The microtubule (MT) network is an essential regulator of insulin secretion from pancreatic β cells, which is central to blood-sugar homeostasis. We find that... 
pancreatic beta cells | insulin biogenesis | insulin granule | cytoskeleton | microtubule nucleation | dense-core granules | Golgi | insulin secretion | diabetes | EPAC | CYCLIC-AMP | TRANSPORT | PROTEIN | STIMULATION | CENTROSOME | BIOCHEMISTRY & MOLECULAR BIOLOGY | INSULIN GRANULE DYNAMICS | NUCLEATION | DYSFUNCTION | PROINSULIN SYNTHESIS | CAMP | CELL BIOLOGY | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 12/2012, Volume 120, Issue 25, pp. 5032 - 5040
Journal Article