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1. Full Text Grapefruit Juice and Statins
by Lee, Jonathan W., BS and Morris, Joan K., PhD and Wald, Nicholas J., FRS
The American journal of medicine, ISSN 0002-9343, 2016, Volume 129, Issue 1, pp. 26 - 29
Internal Medicine | Ischemic heart disease | Drug interaction | Effect enhancer | LDL cholesterol | Grapefruit juice | Statins | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Beverages - adverse effects | Humans | Risk Factors | Citrus paradisi | Heart Diseases - prevention & control | Rhabdomyolysis - etiology | Contraindications | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Anticholesteremic Agents - pharmacokinetics | Anticholesteremic Agents - therapeutic use | Drug Interactions | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Cholesterol, LDL - blood | Heart Diseases - blood | Complications and side effects | Simvastatin | Low density lipoproteins | Heart diseases | Trans fatty acids | Cardiovascular agents | Antilipemic agents | Fruit juices | Cardiovascular disease | Pharmacology | Index Medicus | Abridged Index Medicus
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2. Full Text Grapefruit Juice–Drug Interactions: Grapefruit Juice and Its Components Inhibit P‐Glycoprotein (ABCB1) Mediated Transport of Talinolol in Caco‐2 Cells
by de Castro, Whocely Victor and Mertens‐Talcott, Susanne and Derendorf, Hartmut and Butterweck, Veronika
Journal of pharmaceutical sciences, ISSN 0022-3549, 10/2007, Volume 96, Issue 10, pp. 2808 - 2817
grapefruit juice | P‐glycoprotein | talinolol | ABCB1 | flavonoids | furanocoumarins | P-glycoprotein | Talinolol | Flavonoids | Furanocoumarins | Grapefruit juice | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Chemistry, Multidisciplinary | Science & Technology | Pharmaceutical technology. Pharmaceutical industry | Biological and medical sciences | Medical sciences | General pharmacology | Pharmacology. Drug treatments | Caco-2 Cells | Intestinal Mucosa - metabolism | Furocoumarins - pharmacology | Propanolamines - metabolism | Flavanones - pharmacology | Food-Drug Interactions | Humans | Citrus paradisi | Intestinal Absorption - drug effects | Permeability | Intestinal Mucosa - drug effects | ATP Binding Cassette Transporter, Subfamily B | Dose-Response Relationship, Drug | ATP Binding Cassette Transporter, Subfamily B, Member 1 - antagonists & inhibitors | ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism | Membrane Transport Modulators - pharmacology | Beverages | Index Medicus
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3. Full Text Variation of Flavonoids and Furanocoumarins in Grapefruit Juices:  A Potential Source of Variability in Grapefruit Juice−Drug Interaction Studies
by De Castro, Whocely Victor and Mertens-Talcott, Susanne and Rubner, Anke and Butterweck, Veronika and Derendorf, Hartmut
Journal of agricultural and food chemistry, ISSN 0021-8561, 01/2006, Volume 54, Issue 1, pp. 249 - 255
Grapefruit | Flavonoids | Furanocoumarins | HPLC | Cytochrome P-450 | Grapefruit-drug interaction | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Food Science & Technology | Agriculture, Multidisciplinary | Agriculture | Science & Technology | Fundamental and applied biological sciences. Psychology | Food industries | Biological and medical sciences | Fruit and vegetable industries | Flavonoids - analysis | Chromatography, High Pressure Liquid | Citrus paradisi - chemistry | Furocoumarins - analysis | Flavanones - analysis | Beverages - analysis | Index Medicus
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4. Full Text Clementine juice has the potential for drug interactions – In vitro comparison with grapefruit and mandarin juice
by Theile, Dirk and Hohmann, Nicolas and Kiemel, Dominik and Gattuso, Giuseppe and Barreca, Davide and Mikus, Gerd and Haefeli, Walter Emil and Schwenger, Vedat and Weiss, Johanna
European journal of pharmaceutical sciences, ISSN 0928-0987, 01/2017, Volume 97, pp. 247 - 256
Grapefruit | HPLC-DAD-ESI-MS-MS | Mandarin | Clementine | CYPs | Drug transporters | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Antibiotics, Antitubercular - adverse effects | Citrus sinensis | Fruit and Vegetable Juices - adverse effects | Humans | Citrus paradisi | Tacrolimus - metabolism | Tacrolimus - adverse effects | Food-Drug Interactions - physiology | Citrus | Dose-Response Relationship, Drug | Rifampin - adverse effects | Animals | HEK293 Cells | Antibiotics, Antitubercular - metabolism | Cell Line, Tumor | Immunosuppressive Agents - metabolism | Adult | Female | Immunosuppressive Agents - adverse effects | Mice | Rifampin - metabolism | Citrus fruits | Complications and side effects | Tacrolimus | Analysis | Drug interactions | Cytochrome P-450 | Physiological aspects | Fruit juices | Index Medicus
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5. Full Text A Modified Grapefruit Juice Eliminates Two Compound Classes as Major Mediators of the Grapefruit Juice–Fexofenadine Interaction: An In Vitro–In Vivo “Connect”
by Won, Christina S and Lan, Tian and VanderMolen, Karen M and Dawson, Paul A and Oberlies, Nicholas H and Widmer, Wilbur W and Scarlett, Yolanda V and Paine, Mary F
Journal of clinical pharmacology, ISSN 0091-2700, 09/2013, Volume 53, Issue 9, pp. 982 - 990
gastrointestinal | clinical pharmacology | pharmacokinetics and drug metabolism | clinical research | Clinical pharmacology | Clinical research | Pharmacokinetics and drug metabolism | Gastrointestinal | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Flavonoids - analysis | Humans | Middle Aged | Citrus paradisi | Cercopithecus aethiops | Male | Anti-Allergic Agents - blood | Young Adult | Organic Anion Transporters - genetics | HEK293 Cells | Adult | Female | Terfenadine - blood | Terfenadine - pharmacokinetics | Beverages - analysis | Organic Anion Transporters - antagonists & inhibitors | Fruit | Food-Drug Interactions | Terfenadine - analogs & derivatives | Cross-Over Studies | Anti-Allergic Agents - pharmacokinetics | Coumarins - analysis | Animals | Estrone - analogs & derivatives | Estrone - metabolism | COS Cells | Drug metabolism | Research | Chemical properties | Grapefruit juice | Drug interactions | Index Medicus | pharmacokinetics & drug metabolism | pharmacology
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6. Full Text A furanocoumarin-free grapefruit juice establishes furanocoumarins as the mediators of the grapefruit juice-felodipine interaction
by Paine, Mary F and Widmer, Wilbur W and Hart, Heather L and Pusek, Susan N and Beavers, Kimberly L and Criss, Anne B and Brown, Sherri S and Thomas, Brian F and Watkins, Paul B
The American journal of clinical nutrition, ISSN 0002-9165, 05/2006, Volume 83, Issue 5, pp. 1097 - 1105
Drugs | Grapefruit juice | Intestine | Interaction | First-pass metabolism | Furanocoumarins | CYP3A4 | Metabolism | Felodipine | Life Sciences & Biomedicine | Nutrition & Dietetics | Science & Technology | Fundamental and applied biological sciences. Psychology | Feeding. Feeding behavior | Biological and medical sciences | Vertebrates: anatomy and physiology, studies on body, several organs or systems | Caco-2 Cells | Enzyme Inhibitors | Furocoumarins - pharmacology | Cytochrome P-450 Enzyme Inhibitors | Felodipine - blood | Citrus paradisi - chemistry | Cytochrome P-450 CYP3A | Fruit - chemistry | Humans | Male | Microsomes - enzymology | Intestines - ultrastructure | Drug Interactions | Furocoumarins - analysis | Felodipine - pharmacokinetics | Adult | Female | Furocoumarins - chemistry | Beverages - analysis | Health aspects | Kinetics | Fruit juices | Index Medicus | Abridged Index Medicus
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7. Full Text Effects of ultrasound treatments on quality of grapefruit juice
by Aadil, Rana Muhammad and Zeng, Xin-An and Han, Zhong and Sun, Da-Wen
Food chemistry, ISSN 0308-8146, 12/2013, Volume 141, Issue 3, pp. 3201 - 3206
Cloud value | Grapefruit juice | Bioactive compounds | Ultrasound | Quality | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Nutrition & Dietetics | Food Science & Technology | Science & Technology | Biological and medical sciences | Toxicology | Medical sciences | Food toxicology | Sonication - methods | Phenols - analysis | Flavonoids - analysis | Ascorbic Acid - analysis | Citrus paradisi - chemistry | Food Handling - methods | Antioxidants - analysis | Beverages - analysis | Quality Control | Juice industry | Fruit juices | Index Medicus
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8. Full Text Pomegranate Juice Does Not Impair Clearance of Oral or Intravenous Midazolam, a Probe for Cytochrome P450‐3A Activity: Comparison With Grapefruit Juice
by Farkas, Dora and Oleson, Lauren E and Zhao, Yanli and Harmatz, Jerold S and Zinny, Miguel A and Court, Michael H and Greenblatt, David J
Journal of clinical pharmacology, ISSN 0091-2700, 03/2007, Volume 47, Issue 3, pp. 286 - 294
grapefruit juice | pomegranate juice | drug interactions | cytochrome P450‐3A | midazolam | in vitro metabolism | In vitro metabolism | Midazolam | Cytochrome P450-3A | Grapefruit juice | Pomegranate juice | Drug interactions | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Punicaceae - chemistry | Injections, Intravenous | Administration, Oral | Area Under Curve | Citrus paradisi - chemistry | Food-Drug Interactions | Humans | Microsomes, Liver - metabolism | GABA Modulators - administration & dosage | GABA Modulators - pharmacokinetics | Midazolam - administration & dosage | Male | Metabolic Clearance Rate | Midazolam - pharmacokinetics | Triazolam - analogs & derivatives | Cross-Over Studies | Triazolam - metabolism | Analysis of Variance | Cytochrome P-450 CYP3A - metabolism | GABA Modulators - metabolism | Midazolam - metabolism | Adult | Beverages | Index Medicus
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9. Full Text Effects of grapefruit juice and orange juice components on P‐glycoprotein‐ and MRP2‐mediated drug efflux
by Honda, Yoko and Ushigome, Fumihiko and Koyabu, Noriko and Morimoto, Satoshi and Shoyama, Yukihiro and Uchiumi, Takeshi and Kuwano, Michihiko and Ohtani, Hisakazu and Sawada, Yasufumi
British journal of pharmacology, ISSN 0007-1188, 12/2004, Volume 143, Issue 7, pp. 856 - 864
grapefruit juice | orange juice | MDR1 | MRP2 | vinblastine | furanocoumarins | saquinavir | P‐glycoprotein | transport | polymethoxyflavones | P-glycoprotein | Saquinavir | Polymethoxyflavones | Vinblastine | Grapefruit juice | Orange juice | Furanocoumarins | Transport | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Caco-2 Cells | Propionates - pharmacology | Plant Extracts - chemistry | Cyclosporine - pharmacology | Biological Transport, Active - drug effects | Food-Drug Interactions | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Citrus - chemistry | Calcium Channel Blockers - pharmacology | Verapamil - pharmacology | Quinolines - pharmacology | Vinblastine - pharmacokinetics | Algorithms | Transfection | HIV Protease Inhibitors - pharmacokinetics | Membrane Transport Proteins - genetics | Saquinavir - pharmacokinetics | Membrane Transport Proteins - metabolism | Multidrug Resistance-Associated Proteins - genetics | Beverages | Antineoplastic Agents, Phytogenic - pharmacokinetics | Immunosuppressive Agents - pharmacology | Multidrug Resistance-Associated Proteins - metabolism | Index Medicus | Papers
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