UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
life sciences & biomedicine (99) 99
science & technology (99) 99
humans (89) 89
grk (87) 87
animals (75) 75
gpcr (52) 52
biochemistry & molecular biology (49) 49
phosphorylation (46) 46
signal transduction (42) 42
cell biology (34) 34
receptors, g-protein-coupled - metabolism (34) 34
arrestin (29) 29
desensitization (28) 28
g proteins (24) 24
signal transduction - physiology (24) 24
β-arrestin (21) 21
cell line (20) 20
g protein-coupled receptor (19) 19
g protein-coupled receptor kinase (19) 19
g protein-coupled receptors (19) 19
membrane proteins (19) 19
arrestins - metabolism (18) 18
biophysics (17) 17
grks (17) 17
proteins (17) 17
g-protein-coupled receptor kinases - metabolism (16) 16
internalization (16) 16
kinases (16) 16
protein binding (16) 16
rats (16) 16
beta-arrestins (15) 15
review (15) 15
g-protein-coupled receptor kinase 2 - metabolism (13) 13
neurosciences (13) 13
neurosciences & neurology (13) 13
pharmacology & pharmacy (13) 13
physiological aspects (13) 13
receptors, g-protein-coupled - genetics (13) 13
hek293 cells (12) 12
mice (12) 12
signaling (12) 12
g-protein-coupled receptor (11) 11
pkc (11) 11
signal transduction - drug effects (11) 11
cancer (10) 10
g protein (10) 10
gtp-binding proteins - metabolism (10) 10
phosphorylation - drug effects (10) 10
pkc, protein kinase c (10) 10
protein kinases (10) 10
amino acid sequence (9) 9
biology (9) 9
cell line, tumor (9) 9
cell membrane - metabolism (9) 9
endocytosis (9) 9
gpcr, g protein-coupled receptor (9) 9
gpcr, g-protein-coupled receptor (9) 9
grk, g protein-coupled receptor kinase (9) 9
life sciences (9) 9
ligands (9) 9
male (9) 9
molecular sequence data (9) 9
protein transport (9) 9
protein-serine-threonine kinases - metabolism (9) 9
receptors (9) 9
analysis (8) 8
cyclic amp-dependent protein kinases - metabolism (8) 8
g protein-coupled receptor kinases (8) 8
g-protein-coupled receptor kinases - genetics (8) 8
gfp, green fluorescent protein (8) 8
gpcrs (8) 8
heart failure (8) 8
hypertension (8) 8
inflammation (8) 8
models, biological (8) 8
phosphotransferases (8) 8
receptor (8) 8
research article (8) 8
aging (7) 7
arrestins - genetics (7) 7
beta-adrenergic receptor kinases (7) 7
cell signaling (7) 7
cells, cultured (7) 7
g-protein-coupled receptor kinase (7) 7
g-protein-coupled receptor kinase 5 - metabolism (7) 7
molecular biology (7) 7
morphine (7) 7
protein structure, tertiary (7) 7
receptor desensitization (7) 7
transfection (7) 7
arrestins (6) 6
chemistry (6) 6
cyclic amp - metabolism (6) 6
dopamine (6) 6
gpcr kinase (6) 6
hormones, hormone substitutes, and hormone antagonists (6) 6
immunohistochemistry (6) 6
immunology (6) 6
pharmacology (6) 6
receptors, g-protein-coupled - chemistry (6) 6
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


The Journal of biological chemistry, ISSN 0021-9258, 2014, Volume 289, Issue 36, pp. 25262 - 25275
Journal Article
British journal of pharmacology, ISSN 0007-1188, 01/2009, Volume 153, Issue S1, pp. S379 - S388
Journal Article
Biochimica et biophysica acta. Biomembranes, ISSN 0005-2736, 04/2007, Volume 1768, Issue 4, pp. 913 - 922
Journal Article
Seminars in cancer biology, ISSN 1044-579X, 02/2018, Volume 48, pp. 78 - 90
Abstract Increasing evidences point to G protein-coupled receptor kinases (GRKs), a subfamily of protein kinase A/G/C-like kinases, as relevant players in cancer progression, in a cell-type and tumor-specific way... 
Hematology, Oncology and Palliative Medicine | Signaling pathways | GPCR | G protein-coupled receptor kinases (GRKs) | GRK2 | Tumor microenvironment | Life Sciences & Biomedicine | Oncology | Science & Technology | Development and progression | Metastasis | G proteins | Protein kinases | Cancer | Membrane proteins | Index Medicus
Journal Article
International immunopharmacology, ISSN 1567-5769, 11/2013, Volume 17, Issue 3, pp. 638 - 650
Neutrophils play a critical role in the host defense against bacterial and fungal infections, but their inappropriate activation also contributes to tissue... 
Signaling | Receptors | Inflammation | Kinases | Neutrophils | Pharmacology & Pharmacy | Immunology | Life Sciences & Biomedicine | Science & Technology | Signal Transduction - immunology | Animals | Receptors, Cell Surface - immunology | Humans | Neutrophils - immunology | Selectins - immunology | Mycoses | Lectins | Fc receptors | Integrins | Index Medicus | FcR, Fc-receptor | GPI, glycosylphosphatidylinositol anchor | CLEC, C-type lectin | OSCAR, osteoclast-associated receptor | PKB, protein kinase B | DAG, diacyl-glycerol | Tyk2, tyrosine protein kinase 2 | VCAM-1, vascular cell adhesion molecule 1 | ICAM-1, intercellular adhesion molecule 1 | FADD, Fas-associated protein with death domain | IκB, inhibitor of NF-κB | GM-CSF, granulocyte | MyD88, myeloid differentiation protein 88 | TNF, tumor necrosis factor | LTβ, lymphotoxin β | TRADD, TNFR1-associated death domain protein | Abl, Abelson leukemia proto-oncogene | SLP-76, SH2 domain-containing leukocyte protein of 76 kDa | CALDAG-GEFI, calcium and DAG-regulated guanine nucleotide exchange factor I | IL, interleukin | Src, Rous sarcoma virus proto-oncogene | IRF, IFN regulatory factor | RIG, retinoic acid-inducible gene | PLC, phospholipase C | TCR, T-cell receptor | IKK, IκB kinase | ITAM, immunoreceptor tyrosine-based activation motif | CARD, caspase activation and recruitment domain | IP3, inositol-tris-phosphate | CHO, Chinese hamster ovary cells | MKK, MAP kinase kinase | fMLP, formly-Met-Leu-Phe | TRAF, TNF receptor-associated factor | MIP, macrophage inflammatory protein | Rac, Ras-related C3 botulinum toxin substrate | monocyte colony-stimulating factor | PIP3, phosphatidylinositol-3-phosphate | VLA-4, very late antigen 4 (α4β1 integrin) | PAF, platelet activating factor | STAT, signal transducer and activator of transcription | TAK, TGFβ-activated kinase 1 | Mac-1, macrophage antigen 1 (αMβ2 integrin) | FcRγ, Fc-receptor γ-chain | Asc, apoptosis-associated speck-like protein containing a CARD | cIAP, cellular inhibitor of apoptosis | BCR, B-cell receptor | Fgr, Gardner–Rasheed feline sarcoma proto-oncogene | VASP, vasodilator-stimulated phosphoprotein | Hck, hematopoietic cell kinase | TGFβ, transforming growth factor β | Rap, Ras-related protein | SHP-1, SH2 domain-containing protein tyrosine phosphatase 1 | Syk, spleen tyrosine kinase | GPCR, G protein-coupled receptor | G-CSF, granulocyte colony-stimulating factor | TREM, triggering receptor expressed on myeloid cells | DISC, death-inducing signaling complex | MDL-1, myeloid DAP12-associating lectin 1 | C3G, Crk SH3 domain-binding guanine nucleotide exchange factor (RapGEF1) | NF-κB, nuclear factor κB | ERM, ezrin-radixin-moesin | Epac1, exchange protein activated by cyclic AMP 1 | LTB4, leukotriene B4 | Mcl, macrophage C-type lectin | SAP130, Sin3A-associated protein of 130 kDa | SH2, Src-homology 2 domain | MAP kinase, mitogen-activated protein kinase | PSGL-1, P-selectin glycoprotein ligand | PI3K, phoshoinositide-3-kinase | ADAP, adhesion and degranulation promoting adapter protein (Fyb, SLAP-130) | NLRP3, NOD-like receptor family, pyrin domain containing 3 | MDA5, melanoma differentiation-associated protein 5 | TLR, Toll-like receptor | GRK, GPCR kinase | LAD, leukocyte adhesion deficiency | MAPKAP-kinase, MAP kinase-associated protein kinase | ZAP-70, ζ-chain-associated protein of 70 kDa | TRAIL, TNF-related apoptosis-inducing ligand | JNK, c-Jun N-terminal kinase | LFA-1, lymphocyte function-associated receptor 1 (αLβ2 integrin) | ROS, reactive oxygen species | RIP3, receptor-interacting serine-threonine protein kinase 3 | DAP12, DNAX activating protein 12 | IFN, interferon | PIR, paired immunoglobulin-like receptor | PKC, protein kinase C | PAK, p21-activated kinase | ESL-1, E-selectin ligand 1 | GAP, GTPase activating protein | ERK, extracellular signal-regulated kinase | SOCS, suppressor of cytokine signaling | JAK, Janus kinase | RANK, receptor activator of NF-κB | IRAK, IL-1 receptor-associated kinase | NOD, nucleotide-binding oligomerization domain containing protein | CEACAM3, carcinoembryonic antigen-related cell adhesion molecule 3 (CD66b)
Journal Article
Structure (London), ISSN 0969-2126, 12/2019, Volume 27, Issue 12, pp. 1862 - 1874.e7
... in a “plug and play” fashion. sABs were also generated to a representative of another class of GPCR signaling partner, G protein receptor kinase 1 (GRK1... 
phage display | affinity maturation | GRK (G protein receptor kinase) | SP cryo-EM | universal fiducial mark | synthetic antibodies | GPCR | G proteins | interface energetics | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Index Medicus
Journal Article