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11/2008
Glycogen Synthase Kinase-3 (GSK-3) is a highly conserved serine/threonine kinase comprised of two mammalian homologues, GSK-3α and β, encoded by independent... 
BCLAF1 | GSK-3 | 0307
Dissertation
Theriogenology, ISSN 0093-691X, 01/2020, Volume 141, pp. 62 - 67
Primordial germ cells (PGCs) are precursors of sperms and oocytes and responsible for passing the genetic information from one generation to the next. Chicken... 
GSK-3 | Proliferation | Chicken PGCs | Apoptosis
Journal Article
Journal Article
Journal of Alzheimer's Disease, ISSN 1387-2877, 2010, Volume 19, Issue 4, pp. 1221 - 1229
Journal Article
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ISSN 0892-6638, 02/2019, Volume 33, Issue 2, pp. 2072 - 2083
Insulin is a critical signaling molecule in reducing blood glucose levels, and pyruvate dehydrogenase (PDH) is an essential enzyme in regulating glucose... 
GSK-3β | GTPase | hepatocellular carcinoma | TRANSLOCATION | TYROSINE PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLYCOGEN-SYNTHASE KINASE-3 | MUSCLE | GSK-3 | BETA | CELL BIOLOGY | SIGNAL-TRANSDUCTION | COMPLEX ACTIVITY | LIVER | BIOLOGY | GSK-3 beta | PROMOTES
Journal Article
Cancer Biology & Therapy, ISSN 1538-4047, 08/2019, Volume 20, Issue 8, pp. 1047 - 1056
As a kinase at the crossroads of numerous metabolic and cell growth signaling pathways, glycogen synthase kinase-3 beta (GSK-3β) is a highly desirable... 
clinical trial | GSK-3β | cancer | immunotherapy | C-MYC | FACTOR-KAPPA-B | CELL-PROLIFERATION | GSK-3 | HUMAN PANCREATIC-CANCER | EPITHELIAL-MESENCHYMAL TRANSITION | ONCOLOGY | WNT/BETA-CATENIN | THERAPEUTIC TARGET | GSK3-BETA | GSK-3 beta | EXPRESSION
Journal Article
BBA - General Subjects, ISSN 0304-4165, 10/2016, Volume 1860, Issue 10, pp. 2076 - 2085
Hypoxia-ischemia is an important cause of brain injury and neurological morbidity in the newborn infants. The activity of glycogen synthase kinase-3β (GSK-3β)... 
GSK-3β | Neuroprotection | Tideglusib | Neonatal hypoxia–ischemia | Apoptosis | MOUSE-BRAIN | NEURONAL APOPTOSIS | ACTIVATION | Neonatal hypoxia-ischemia | BIOCHEMISTRY & MOLECULAR BIOLOGY | GSK-3 | GLYCOGEN-SYNTHASE KINASE-3-BETA | PERIINFARCT AREA | STROKE | BIOPHYSICS | SIGNALING PATHWAY | IN-VIVO | GSK-3 beta | CEREBRAL-ISCHEMIA
Journal Article
Journal Article
Chemico-Biological Interactions, ISSN 0009-2797, 12/2019, Volume 314, p. 108823
Journal Article
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ISSN 0006-291X, 05/2019, Volume 513, Issue 1, pp. 226 - 233
Hyperglycemia-induced proximal tubule injury plays a critical role in the pathogenesis of diabetic nephropathy (DN). Attenuating high glucose (HG)-induced... 
Mitochondrion | ACTIVATION | BIOPHYSICS | NRF2 | Oxidative damage | BIOCHEMISTRY & MOLECULAR BIOLOGY | Obacunone | GSK-3 beta | High glucose
Journal Article
PARASITE, ISSN 1252-607X, 07/2019, Volume 26, p. 39
Glycogen synthase kinase 3 (GSK-3), which belongs to the serine/threonine kinase family, regulates glycogen metabolism, Wnt signaling, hormonal regulation, and... 
PATHWAYS | RNA interference | PROTEIN | PHOSPHORYLATION | Cloning | Vaccine | GSK-3 | KINASE 3-BETA | DIGESTION | DISEASES | Real-time PCR | TICKS | GSK-3 beta | EXPRESSION | PARASITOLOGY | GSK-3β
Journal Article
Journal of neuroinflammation, ISSN 1742-2094, 02/2019, Volume 16, Issue 1, pp. 24 - 16
BackgroundPrevious studies had showed that Apelin 13 could protect against apoptosis induced by ischemic/reperfusion (I/R). However, the mechanisms whereby... 
Oxidative stress | Apelin 13 | AMPK/GSK-3β/Nrf2 | Inflammation | Ischemic stroke | PROTEIN-KINASE | REPERFUSION INJURY | TRANSIENT MODEL | IMMUNOLOGY | NEUROSCIENCES | GSK-3 beta/Nrf2 | APJ RECEPTOR | TRANSCRIPTION FACTOR NRF2 | AMPK | LIGAND | CEREBRAL-ISCHEMIA | BRAIN | ISCHEMIA/REPERFUSION
Journal Article
International Journal of Clinical and Experimental Medicine, ISSN 1940-5901, 04/2015, Volume 8, Issue 4, pp. 5897 - 5903
Glycogen synthase kinase 3 beta (GSK-3 beta) protein is a key regulator of neurogenesis, neuronal differentiation and polarisation during neurodevelopment.... 
Development | GSK-3β | Dorsal root ganglion | Neurogenesis | P-GSK-3β (S9) | SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | SYNTHASE KINASE-3-BETA | development | GSK-3 | SENSORY NEURONS | REGULATOR | INHIBITION | ROLES | dorsal root ganglion | GROWTH | p-GSK-3 beta (S9) | neurogenesis | GSK-3 beta
Journal Article
Life Sciences, ISSN 0024-3205, 08/2018, Volume 207, pp. 532 - 549
Colorectal cancer (CRC) remains one of the most lethal human malignancies with high incidence and lack of effective therapy. Raddeanin A (RA), an active... 
GSK-3β | Wnt/β-catenin pathway | Raddeanin A (RA) | Colorectal cancer (CRC) | NF-κB pathway | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | NF-kappa B pathway | Wnt/beta-catenin pathway | TUMOR | COMPONENTS | PROLIFERATION | MECHANISMS | GSK-3 | SUPPRESSION | SYNTHASE | ROLES | PHARMACOLOGY & PHARMACY | GSK-3 beta | WNT
Journal Article
American Journal of Chinese Medicine, ISSN 0192-415X, 2017, Volume 45, Issue 8, pp. 1667 - 1682
Caveolin-1, the marker protein of membranal caveolae, is not only involved in cholesterol regulation, but also participates in the cleavage of amyloid... 
Caveolin-1 | Tau | Curcumin | Alzheimer's Disease | GSK-3 β | PHOSPHORYLATION | KINASE | GSK-3 | PATHOLOGY | MEDICINE, GENERAL & INTERNAL | PATHWAY | INTEGRATIVE & COMPLEMENTARY MEDICINE | GSK-3 beta | BRAIN
Journal Article
Neuroscience Letters, ISSN 0304-3940, 2009, Volume 455, Issue 3, pp. 191 - 194
We have previously demonstrated that Leptin reduces extracellular amyloid β (Aβ) protein both and , and intracellular tau phosphorylation . Further, we have... 
GSK-3β | Tau | AICAR | Alzheimer's disease | Leptin | ALZHEIMERS-DISEASE | GSK-3 beta | LITHIUM | NEUROSCIENCES | tau | Alzheimer’s disease
Journal Article