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Biological Psychiatry, ISSN 0006-3223, 03/2017, Volume 81, Issue 6, pp. 478 - 483
What makes the molecular study of psychiatric and other neurological conditions particularly challenging compared with other complex traits is the difficulty... 
Epigenetics | Regulatory | GTEx | PsychENCODE | Roadmap | ENCODE
Journal Article
International journal of molecular sciences, ISSN 1422-0067, 05/2019, Volume 20, Issue 9, p. 2228
Ubiquitination is one of the main post-translational modification of proteins. It plays key roles in a broad range of cellular functions, including protein... 
GTEx | GEPIA | UALCAN | overexpression | UBE2C | cancer | TCGA
Journal Article
by Kahles, André and Lehmann, Kjong-Van and Toussaint, Nora C and Hüser, Matthias and Stark, Stefan G and Sachsenberg, Timo and Stegle, Oliver and Kohlbacher, Oliver and Sander, Chris and Caesar-Johnson, Samantha J and Demchok, John A and Felau, Ina and Kasapi, Melpomeni and Ferguson, Martin L and Hutter, Carolyn M and Sofia, Heidi J and Tarnuzzer, Roy and Wang, Jing and Wang, Timothy and Wang, Min and Wang, Jioajiao and Wang, Zhining and Wang, Linghua and Yang, Ju Dong and Yang, Liming and Yang, Ian and Yang, Hannah and Zenklusen, Jean C and Zhang, Jiashan (Julia) and Zhang, Hailei and Zhang, Wei and Zhang, Jiexin and Zhang, Hongxin and Zhang, Lizhi and Zhang, Hongzheng and Chudamani, Sudha and Liu, Jia and Liu, Yuexin and Liu, Xiuping and Liu, Wenbin and Lolla, Laxmi and Naresh, Rashi and Pihl, Todd and Sun, Qiang and Sun, Yichao and Wan, Yunhu and Wu, Ye and Cho, Juok and DeFreitas, Timothy and Frazer, Scott and Gehlenborg, Nils and Getz, Gad and Heiman, David I and Kim, Jaegil and Lawrence, Michael S and Lin, Pei and Meier, Sam and Noble, Michael S and Saksena, Gordon and Voet, Doug and Bernard, Brady and Chambwe, Nyasha and Dhankani, Varsha and Knijnenburg, Theo and Kramer, Roger and Leinonen, Kalle and Miller, Christopher A and Miller, Michael and Miller, Judy and Reynolds, Sheila and Shmulevich, Ilya and Thorsson, Vesteinn and Akbani, Rehan and Broom, Bradley M and Hegde, Apurva M and Ju, Zhenlin and Kanchi, Rupa S and Korkut, Anil and Li, Jun and Li, Wei and Liang, Han and Ling, Shiyun and Lu, Yiling and Mills, Gordon B and Ng, Kwok-Shing and Rao, Arvind and Ryan, Michael and Weinstein, John N and Abeshouse, Adam and Armenia, Joshua and Chakravarty, Debyani and Chatila, Walid K and de Bruijn, Ino and Gao, Galen F and Gao, Jianjiong and Gross, Benjamin E and Heins, Zachary J and Kundra, Ritika and La, Konnor and Ladanyi, Marc and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network
Cancer Cell, ISSN 1535-6108, 08/2018, Volume 34, Issue 2, pp. 211 - 224.e6
Our comprehensive analysis of alternative splicing across 32 The Cancer Genome Atlas cancer types from 8,705 patients detects alternative splicing events and... 
tumor-specific splicing | GTEx | alternative splicing | MS proteomics | neoantigens | TCGA | exome | RNA-seq | immunotherapy | splicing QTL | cancer | CPTAC | TCGA Pan-Cancer Atlas | immunoediting | Oncology | Cell Biology | Cancer Research | BREAST-CANCER | COWDEN-SYNDROME | MET INHIBITORS | VARIANTS | ONCOLOGY | PTEN | OVARIAN-CANCER | IDENTIFICATION | SOMATIC MUTATIONS | MASS-SPECTROMETRY | REVEALS | CELL BIOLOGY
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 09/2017, Volume 114, Issue 37, pp. E7841 - E7850
Characterizing the collective regulatory impact of genetic variants on complex phenotypes is a major challenge in developing a genotype to phenotype map. Using... 
GTEx | Expression quantitative trait locus | GWAS | Bipartite networks | eQTL | expression quantitative trait locus | ASSOCIATIONS | TRANS-EQTLS | MULTIDISCIPLINARY SCIENCES | DISEASE | GENE-EXPRESSION | LOCI | bipartite networks | Biological Sciences | PNAS Plus
Journal Article
Journal Article
Cell Reports, ISSN 2211-1247, 10/2017, Volume 21, Issue 4, pp. 1077 - 1088
Although all human tissues carry out common processes, tissues are distinguished by gene expression patterns, implying that distinct regulatory programs... 
GTEx | gene regulation | transcription factors | transcriptome | transcriptional regulation | tissue specificity | network medicine | regulatory networks | network biology | gene expression | CELLS | COEXPRESSION NETWORK ANALYSIS | TBX20 | ARCHITECTURE | DIFFERENTIATION | EXPRESSION | REVEALS | ACTS | CELL BIOLOGY
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 06/2019, Volume 104, Issue 6, pp. 1013 - 1024
Adipose tissue is an important endocrine organ with a role in many cardiometabolic diseases. It is comprised of a heterogeneous collection of cell types that... 
GTEx | genetics | cell type composition | TwinsUK | transcriptomics | genomics | adipose | eQTL | obesity | interactions | Metabolic diseases | Genetic aspects | Genetic transcription | Research | Gene expression
Journal Article
Frontiers in Genetics, ISSN 1664-8021, 09/2019, Volume 10
The genetic component of many common traits is associated with the gene expression and several variants act as expression quantitative loci, regulating the... 
gene expression imputation | GTEx | deep learning | support vector machine | eQTL | variational autoencoder
Journal Article
BMC GENOMICS, ISSN 1471-2164, 01/2019, Volume 20, Issue 1, pp. 26 - 13
BackgroundThere is great interest to study how gene pathways change their structure across different tissues. The assessment of inter-study reliability of... 
Brain | GTEx | Coehn's kappa | Transcriptome | Co-expression networks | RNA-sequencing | Addiction | KAPPA | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | Reliability | Nicotine | BRAINS | Genetic research | Brain research | Research | Gene expression | Coehn’s kappa
Journal Article
DIAGNOSTIC PATHOLOGY, ISSN 1746-1596, 10/2019, Volume 14, Issue 1, pp. 1 - 16
Background Protein arginine methyltransferase-1 (PRMT1) is associated with the progression of various tumor types and the process of epithelial to mesenchymal... 
Renal cell tumors | EPITHELIAL-MESENCHYMAL-TRANSITION | GTEx | REGULATOR | PRMT1 | POOR-PROGNOSIS | PATHOLOGY | EMT | CANCER | TCGA | RUNX1 | TWIST
Journal Article