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Journal Article
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 10/2014, Volume 73, Issue 10, pp. 1888 - 1897
Objective Accumulation of mitochondria underlies T-cell dysfunction in systemic lupus erythematosus (SLE). Mitochondrial turnover involves endosomal traffic... 
Autoimmunity | Systemic Lupus Erythematosus | Autoimmune Diseases | RAPAMYCIN | SYSTEMIC-LUPUS-ERYTHEMATOSUS | REVISED CRITERIA | T-CELL-ACTIVATION | REDUCES DISEASE-ACTIVITY | MAMMALIAN AUTOPHAGY | NITRIC-OXIDE | HYPERPOLARIZATION | FISSION | RHEUMATOLOGY | ENDOGENOUS RETROVIRUS | Dynamins - blood | Humans | Autophagy - physiology | Lupus Erythematosus, Systemic - blood | Case-Control Studies | rab4 GTP-Binding Proteins - physiology | Mice, Inbred MRL lpr | Lysosomes - metabolism | Dynamins - physiology | T-Lymphocytes - metabolism | Lupus Erythematosus, Systemic - drug therapy | Lupus Erythematosus, Systemic - immunology | Diphosphonates - therapeutic use | Mitochondrial Degradation - immunology | Female | Molecular Targeted Therapy - methods | Pyridines - therapeutic use | Microtubule-Associated Proteins - blood | GTP Phosphohydrolases - physiology | Jurkat Cells | Cells, Cultured | Mitochondrial Proteins - physiology | Mitochondria - metabolism | Microtubule-Associated Proteins - physiology | Animals | Mitochondrial Proteins - blood | Homeostasis - physiology | GTP Phosphohydrolases - blood | Care and treatment | Systemic lupus erythematosus | Pathogenic microorganisms | Analysis | Homeostasis | Diagnosis | Research | Lupus | Antigens | Immunoglobulins | Blood & organ donations | Pathogenesis | T cell receptors | Gene expression | Autophagy | Proteins | Mitochondria | Lymphocytes | Fibroblasts | Basic and Translational Research | 1506
Journal Article
Nature Medicine, ISSN 1078-8956, 03/2012, Volume 18, Issue 3, pp. 441 - 445
Celiac disease is an immune-mediated disorder in which mucosal autoantibodies to the enzyme transglutaminase 2 (TG2)(1) are generated in response to the... 
MEDICINE, RESEARCH & EXPERIMENTAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | GERMINAL-CENTER | CELL BIOLOGY | MEMORY B-CELLS | PEPTIDES | AFFINITY | IMMUNE-RESPONSES | HUMAN MONOCLONAL-ANTIBODIES | TISSUE TRANSGLUTAMINASE | ASSOCIATION | RAPID GENERATION | ANTIGEN | Glutens - immunology | Immunoglobulin G - blood | Autoantibodies - blood | Humans | Transglutaminases - blood | Immunoglobulin M - immunology | HLA-DQ Antigens - immunology | Immunoglobulin D - immunology | Transglutaminases - immunology | Celiac Disease - immunology | Immunoglobulin G - immunology | Intestinal Mucosa - immunology | Intestinal Mucosa - enzymology | Escherichia coli - metabolism | Celiac Disease - blood | Plasma Cells - metabolism | Single-Cell Analysis | Somatic Hypermutation, Immunoglobulin | GTP-Binding Proteins - immunology | Autoantibodies - immunology | Immunoglobulin D - blood | Antibody-Producing Cells - immunology | B-Lymphocytes - immunology | Immunoglobulin M - blood | GTP-Binding Proteins - blood | Escherichia coli - genetics | Immunoglobulin A - immunology | Transglutaminases - metabolism | Immunoglobulin A - blood | Mutation | GTP-Binding Proteins - metabolism | Plasma Cells - immunology | Immune response | Gastrointestinal diseases | Colorectal diseases | Plasma cells | Physiological aspects | Genetic aspects | Research | Gluten | Health aspects | Risk factors | Celiac disease | Antigens | Enzymes | Cellular biology | Gene expression | Immune system
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 07/2015, Volume 13, Issue 7, pp. 1325 - 1334
Summary Background Platelet secretion is critical to development of acute thrombotic occlusion. Platelet dense granules contain a variety of important... 
secretory granules | blood platelets | biogenesis | Sgk1 protein, mouse | Rab27b protein, mouse | Blood platelets | Biogenesis | Secretory granules | ACTIVATION | EXOCYTOSIS | THROMBUS FORMATION | RELEASE | mouse | TRANSPORT | INHIBITION | POST-GOLGI TRAFFICKING | INFLAMMATION | PERIPHERAL VASCULAR DISEASE | ENDOPLASMIC-RETICULUM | HEMATOLOGY | Rab27b protein | HEMOSTASIS | Sgk1 protein | Protein-Serine-Threonine Kinases - deficiency | Up-Regulation | Carotid Artery Injuries - blood | Adenosine Triphosphate - secretion | Immediate-Early Proteins - blood | Male | rab GTP-Binding Proteins - genetics | Blood Platelets - enzymology | Adenosine Triphosphate - blood | Cytoplasmic Granules - secretion | RNA, Messenger - metabolism | Serotonin - blood | Cytoplasmic Granules - enzymology | Transfection | Time Factors | Tetraspanin 30 - blood | Protein-Serine-Threonine Kinases - blood | Immediate-Early Proteins - deficiency | Female | Carotid Artery Injuries - genetics | Thrombosis - blood | Secretory Vesicles - enzymology | Tetraspanin 30 - secretion | Carotid Artery Injuries - pathology | Disease Models, Animal | rab GTP-Binding Proteins - metabolism | Signal Transduction | Secretory Vesicles - ultrastructure | Thrombosis - enzymology | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Megakaryocytes - secretion | Genotype | Megakaryocytes - enzymology | Blood Platelets - secretion | Mice, Knockout | Platelet Aggregation | Secretory Vesicles - secretion | Thrombosis - pathology | Phenotype | Animals | Carotid Artery Injuries - enzymology | Immediate-Early Proteins - genetics | Cytoplasmic Granules - ultrastructure | Platelet Activation | Blood Platelets - ultrastructure | Serotonin - secretion | Thrombosis - genetics | Biosynthesis | Corticosteroids | Carrier proteins | RNA | Analysis | Steroids | Serotonin | Rodents | Blood clots
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 04/2015, Volume 13, Issue 4, pp. 619 - 630
Journal Article