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Journal of Clinical Investigation, ISSN 0021-9738, 04/2015, Volume 125, Issue 4, pp. 1419 - 1432
The small GTPase RAP1 is critical for platelet activation and thrombus formation. RAP1 activity in platelets is controlled by the GEF CalDAG-GEFI and an... 
GENE-MUTATIONS | MEDICINE, RESEARCH & EXPERIMENTAL | PROTEIN-KINASE-C | ADENOSINE-DIPHOSPHATE | ALPHA-IIB-BETA-3 ACTIVATION | MICE | CALDAG-GEFI | PLASMA-MEMBRANE | ADENYLATE-CYCLASE | ADP | MOUSE MODELS | Thrombopoiesis | Ticlopidine - pharmacology | rap1 GTP-Binding Proteins - antagonists & inhibitors | Platelet Activation - physiology | Thrombocytopenia - surgery | Splenectomy | Thrombocytopenia - genetics | Cellular Senescence | Hemostasis | Platelet Aggregation Inhibitors - pharmacology | GTPase-Activating Proteins - physiology | Guanine Nucleotide Exchange Factors - deficiency | Mice, Inbred C57BL | Receptors, Purinergic P2Y12 - physiology | Proto-Oncogene Proteins c-akt - physiology | Ticlopidine - analogs & derivatives | Mice, Knockout | Platelet Activation - genetics | Animals | rap1 GTP-Binding Proteins - physiology | Saphenous Vein - injuries | Clopidogrel | Mice | Mice, Inbred BALB C | Platelet Activation - drug effects | GTPase-Activating Proteins - genetics | Lymphopenia - genetics | Cell receptors | Development and progression | Cellular signal transduction | Genetic aspects | Properties | Health aspects | Blood platelet disorders | Heart attacks | Laboratories | Cloning | Thrombosis | Embryos | Proteins | Studies | Blood platelets | Rodents | Technological change | Protein expression | Mutation | Infrared imaging systems | Veins & arteries | Index Medicus | Abridged Index Medicus
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Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 4/2010, Volume 189, Issue 2, pp. 223 - 232
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Journal Article
Gastroenterology, ISSN 0016-5085, 2017, Volume 152, Issue 4, pp. 851 - 866.e24
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Journal Article
The Plant Cell, ISSN 1040-4651, 5/2007, Volume 19, Issue 5, pp. 1682 - 1694
Journal Article
Immunology and Cell Biology, ISSN 0818-9641, 09/2017, Volume 95, Issue 8, pp. 729 - 735
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, pp. e88772 - e88772
Background: The ability of human bone marrow mesenchymal stem cells (BM-MSCs) to migrate and localize specifically to injured tissues is central in developing... 
BREAST-CANCER | CLEAVING ENZYME | IN-VITRO | DIFFERENTIAL EXPRESSION | MULTIDISCIPLINARY SCIENCES | NECROSIS-FACTOR-ALPHA | SERINE-PROTEASE | ACTIN CYTOSKELETON | STROMAL CELLS | TUMOR-GROWTH | SEPRASE | Interleukin-1beta - pharmacology | Humans | rhoA GTP-Binding Protein - metabolism | rhoA GTP-Binding Protein - genetics | Genetic Complementation Test | Membrane Proteins - deficiency | Mesenchymal Stromal Cells - cytology | Serine Endopeptidases - genetics | Bone Marrow Cells - drug effects | Gelatinases - deficiency | Cell Line | Mesenchymal Stromal Cells - drug effects | Gelatinases - antagonists & inhibitors | Serine Endopeptidases - deficiency | Signal Transduction | Bone Marrow Cells - cytology | Membrane Proteins - genetics | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | Mesenchymal Stromal Cells - metabolism | rhoA GTP-Binding Protein - antagonists & inhibitors | Chemotaxis | Transforming Growth Factor beta - pharmacology | Membrane Proteins - antagonists & inhibitors | Gelatinases - genetics | Primary Cell Culture | Bone Marrow Cells - metabolism | Thrombin | Bone morphogenetic proteins | Interleukins | Transforming growth factors | Health aspects | Stem cells | Biotechnology | Mesenchyme | Serine | Transforming growth factor-b | Interleukin | Activation | Kinases | Tissues | Cell surface | Cell adhesion & migration | Proteins | Embryogenesis | Bone marrow | Fibroblasts | Tumor necrosis factor-TNF | Inhibition | Growth factors | Medical research | Peptidase | Cytokines | Research & development--R&D | RhoA protein | Inflammation | IL-1β | Gene expression | Fibroblast activation protein | Embryonic growth stage | Regeneration | Depletion | Inhibitors | Human performance | Protein expression | Serine proteinase | Bone | Cell migration | Tumors | Cancer | Guanosinetriphosphatase | Pharmaceuticals | Index Medicus | Research & development | R&D
Journal Article
The EMBO Journal, ISSN 0261-4189, 01/2018, Volume 37, Issue 1, pp. 1 - 18
Journal Article