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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2013, Volume 110, Issue 14, pp. 5510 - 5515
Journal Article
Journal Article
The Journal of Physiology, ISSN 0022-3751, 10/2013, Volume 591, Issue 20, pp. 5107 - 5123
Journal Article
Science, ISSN 0036-8075, 03/2018, Volume 359, Issue 6383, pp. 1533 - 1536
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2012, Volume 109, Issue 45, pp. 18613 - 18618
Journal Article
06/2014
The Rho family small GTPases are key regulators of the cytoskeleton, through which they impact and control many vital cellular functions, including growth,... 
Tumour Necrosis Factor-alpha (TNF) | Rho GTPases | 0379 | Hyperosmotic stress | GEF-H1 | 0307 | Cytoskeletal remodelling | Guanine Nucleotide Exchange Factors
Dissertation
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 29, pp. 12220 - 12231
First messenger-dependent activation of MAP kinases in neuronal and endocrine cells is critical for cell differentiation and function and requires guanine... 
R-RAS | CYCLIC-AMP | COCAINE ADDICTION | SPECIFICITY | PATHWAY | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | P38 MAPK | PC12 CELLS | SIGNAL-REGULATED KINASE | RECEPTOR TYROSINE KINASE | rap GTP-Binding Proteins - antagonists & inhibitors | ras Proteins - genetics | Phosphorylation | ras Proteins - metabolism | Green Fluorescent Proteins - genetics | GTP-Binding Proteins - genetics | Neurogenesis | Protein Prenylation | MAP Kinase Signaling System | rap GTP-Binding Proteins - agonists | Neuroendocrine Cells - cytology | RNA Interference | Guanine Nucleotide Exchange Factors - metabolism | rap GTP-Binding Proteins - genetics | Neuroendocrine Cells - metabolism | Cyclic AMP - metabolism | Recombinant Proteins - metabolism | Green Fluorescent Proteins - metabolism | Nerve Tissue Proteins - antagonists & inhibitors | GTP-Binding Proteins - chemistry | Nerve Tissue Proteins - agonists | ras Proteins - antagonists & inhibitors | Rats | Neurites - metabolism | Monomeric GTP-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Monomeric GTP-Binding Proteins - antagonists & inhibitors | Nerve Tissue Proteins - metabolism | Animals | Monomeric GTP-Binding Proteins - metabolism | Cell Line, Tumor | Ligands | Protein Processing, Post-Translational | Enzyme Activation | rap GTP-Binding Proteins - metabolism | GTP-Binding Proteins - metabolism | Index Medicus | Signal Transduction | p38 | cAMP | p38 MAPK | small GTPase | ERK | guanine nucleotide exchange factor (GEF)
Journal Article
Journal Article
ELIFE, ISSN 2050-084X, 04/2015, Volume 4, pp. e07314 - e07314
The general translation initiation factor eIF2 is a major translational control point. Multiple signaling pathways in the integrated stress response... 
GUANINE-NUCLEOTIDE-EXCHANGE | UNFOLDED PROTEIN RESPONSE | 40S RIBOSOMAL-SUBUNIT | OPEN READING FRAMES | MESSENGER-RNA | BIOLOGY | TRANSLATION INITIATION | INITIATION-FACTOR EIF2B | VANISHING WHITE-MATTER | MAMMALIAN-CELLS | GENETIC INTERACTION MAPS | RNA, Small Interfering - genetics | Phosphorylation | Humans | Thapsigargin - antagonists & inhibitors | Acetamides - pharmacology | Structure-Activity Relationship | Protein Subunits - metabolism | Acetamides - chemical synthesis | Neuroprotective Agents - pharmacology | Cyclohexylamines - pharmacology | Eukaryotic Initiation Factor-2B - genetics | HEK293 Cells | Binding Sites | Genes, Reporter | Protein Subunits - genetics | Gene Expression | Neuroprotective Agents - chemistry | Cyclohexylamines - chemical synthesis | Endoplasmic Reticulum Stress - drug effects | Bacterial Proteins - genetics | Cyclohexylamines - chemistry | Nootropic Agents - chemical synthesis | Nootropic Agents - chemistry | Neuroprotective Agents - chemical synthesis | Acetamides - chemistry | High-Throughput Screening Assays | K562 Cells | Protein Binding | Thapsigargin - pharmacology | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Eukaryotic Initiation Factor-2B - metabolism | Protein Subunits - antagonists & inhibitors | HeLa Cells | Eukaryotic Initiation Factor-2B - antagonists & inhibitors | Nootropic Agents - pharmacology | Protein Multimerization - drug effects | Luminescent Proteins - metabolism | RNA, Small Interfering - metabolism | Cell culture | Transcription factors | Neurodegenerative diseases | Serine | Translation initiation | Cognitive ability | Kinases | Proteins | Protein synthesis | Stress response | Dimerization | Long-term depression | Binding sites | Index Medicus
Journal Article