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Nature Reviews Molecular Cell Biology, ISSN 1471-0072, 12/2009, Volume 10, Issue 12, pp. 866 - 876
Directed evolution circumvents our profound ignorance of how a protein's sequence encodes its function by using iterative rounds of random mutation and artificial selection to discover new and useful proteins... 
STRUCTURE-GUIDED RECOMBINATION | SUBSTRATE SPECIFICITIES | IN-VITRO EVOLUTION | LABORATORY EVOLUTION | SEQUENCE SPACE | COMPUTATIONAL DESIGN | METABOLIC PATHWAYS | RNA ENZYME | CATALYTIC-ACTIVITY | RED FLUORESCENT PROTEIN | CELL BIOLOGY | Directed Molecular Evolution | Animals | Proteins - chemistry | Mutation - genetics | Humans | Molecular evolution | Usage | Amino acid sequence | Physiological aspects | Influence | Research | Mutation (Biology)
Journal Article
Critical Reviews in Biotechnology, ISSN 0738-8551, 12/2013, Volume 33, Issue 4, pp. 365 - 378
Journal Article
Journal Article
Journal Article
Frontiers in Plant Science, ISSN 1664-462X, 11/2016, Volume 7, Issue 2016, p. 1683
.... These new technologies increase CRISPR-Cas9's utility and effectiveness by diversifying cellular capabilities through expression construct system evolution and enzyme orthogonality, as well... 
Cpf1 | Plant genome editing | Sequence specific nucleases | CRISPR | RNA-guided endonucleases | Cas9 | plant genome editing | FLORAL-DIP | DIRECTED MUTAGENESIS | GUIDE RNA | AGROBACTERIUM-MEDIATED TRANSFORMATION | PLANT SCIENCES | sequence specific nucleases | DNA | IN-VIVO | HOMOLOGOUS RECOMBINATION | ARABIDOPSIS | TARGETED MUTAGENESIS | HIGH-EFFICIENCY | Genetic aspects | Research | Plants | Prokaryotes | Plant genetics
Journal Article
Current Opinion in Microbiology, ISSN 1369-5274, 2017, Volume 37, pp. 88 - 94
Journal Article
Angewandte Chemie (International ed.), ISSN 1433-7851, 2018, Volume 57, Issue 30, pp. 9238 - 9261
Journal Article