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Journal of Urology, The, ISSN 0022-5347, 2014, Volume 192, Issue 6, pp. 1604 - 1611
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2015, Volume 348, Issue 6234, pp. 581 - 585
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2015, Volume 348, Issue 6242, pp. 1477 - 1481
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2017, Volume 114, Issue 26, pp. 201618421 - E5128
.... In type I-E and II-A CRISPR-Cas systems, this adaptation process is driven by Cas1–Cas2 complexes. Type I-F systems, however, contain a unique fusion of Cas2, with the type I effector helicase and nuclease for invader destruction, Cas3... 
Spacer acquisition | General | Mass spectrometry | Crispr-cas | Horizontal gene transfer | Phage resistance | spacer acquisition | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | ACQUISITION | phage resistance | CAS SYSTEM | horizontal gene transfer | FOREIGN DNA | STRUCTURAL BASIS | CRISPR-Cas | GUIDED SURVEILLANCE COMPLEX | mass spectrometry | REQUIRES | DEGRADATION | HELICASE | INSIGHTS | Methods | Nucleotide sequencing | DNA sequencing | Biological Sciences | PNAS Plus
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 11/2014, Volume 56, Issue 4, pp. 518 - 530
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2017, Volume 114, Issue 26, pp. 201616395 - E5121
Journal Article
Molecular Cell, ISSN 1097-2765, 05/2015, Volume 58, Issue 3, pp. 418 - 430
Journal Article
Current Opinion in Microbiology, ISSN 1369-5274, 2017, Volume 37, pp. 67 - 78
Highlights • Two classes of CRISPR-Cas systems differ by the architectures of effector modules. • Effectors of Class 2 CRISPR-Cas systems are large,... 
Pathology | ADAPTIVE IMMUNITY | ENDONUCLEASE | STRUCTURAL BASIS | CRYSTAL-STRUCTURE | ESCHERICHIA-COLI | GUIDED SURVEILLANCE COMPLEX | MICROBIOLOGY | CLEAVAGE | THERMUS-THERMOPHILUS | RNASE ACTIVITIES | TARGET DNA RECOGNITION | Proteins | Genetic research | Transposons | RNA | Analysis | Genomics
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 05/2018, Volume 46, Issue 8, pp. 4087 - 4098
Abstract In type I CRISPR-Cas systems, primed adaptation of new spacers into CRISPR arrays occurs when the effector Cascade-crRNA complex recognizes imperfectly matched targets that are not... 
IMMUNE-SYSTEM | RNA | STRUCTURAL BASIS | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | GUIDED SURVEILLANCE COMPLEX | TARGET RECOGNITION | INTERFERENCE | CAS SYSTEM | R-LOOP FORMATION | SPACER ACQUISITION | Molecular Biology
Journal Article