X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (241) 241
Publication (34) 34
Book Review (10) 10
Dissertation (2) 2
Book Chapter (1) 1
Conference Proceeding (1) 1
Newspaper Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (180) 180
gadd45a (137) 137
humans (124) 124
apoptosis (92) 92
gadd45a protein (86) 86
animals (84) 84
gene expression (84) 84
nuclear proteins - genetics (78) 78
cell cycle proteins - genetics (74) 74
cancer (66) 66
dna damage (66) 66
mice (64) 64
oncology (64) 64
expression (61) 61
cell cycle (56) 56
genes (54) 54
proteins (54) 54
nuclear proteins - metabolism (53) 53
biochemistry & molecular biology (51) 51
cell biology (50) 50
cell cycle proteins - metabolism (50) 50
female (46) 46
activation (43) 43
deoxyribonucleic acid--dna (43) 43
cell line, tumor (41) 41
p53 (39) 39
signal transduction (37) 37
male (36) 36
dna (34) 34
dna-damage (31) 31
stress (31) 31
dna repair (30) 30
kinases (30) 30
p53 protein (30) 30
analysis (29) 29
dna methylation (29) 29
medicine (29) 29
genotoxicity (28) 28
multidisciplinary sciences (28) 28
transcription (28) 28
biology (27) 27
cell proliferation (26) 26
research article (26) 26
science (25) 25
genetics & heredity (24) 24
cell line (22) 22
protein (22) 22
rodents (22) 22
gene-expression (21) 21
mutation (21) 21
research (21) 21
toxicology (21) 21
tumors (21) 21
transcription factors (20) 20
tumor proteins (20) 20
gene expression profiling (19) 19
genetic aspects (19) 19
induction (19) 19
oxidative stress (19) 19
cells (18) 18
pathway (18) 18
cell death (17) 17
cell growth (17) 17
gene (17) 17
phosphorylation (17) 17
biotechnology & applied microbiology (16) 16
cytotoxicity (16) 16
gene expression regulation, neoplastic (16) 16
genetics (16) 16
growth (16) 16
inhibition (16) 16
methylation (16) 16
middle aged (16) 16
rna (16) 16
tumor suppressor protein p53 - metabolism (16) 16
adult (15) 15
apoptosis - drug effects (15) 15
deoxyribonucleic acid (15) 15
dna demethylation (15) 15
dna microarrays (15) 15
mice, knockout (15) 15
polymerase chain reaction (15) 15
repair (15) 15
transfection (15) 15
tumor suppressor protein p53 - genetics (15) 15
antineoplastic agents - pharmacology (14) 14
biochemistry (14) 14
chromatin (14) 14
damage (14) 14
studies (14) 14
aged (13) 13
article (13) 13
biophysics (13) 13
protein binding (13) 13
rna interference (13) 13
signaling (13) 13
toxicity (13) 13
breast cancer (12) 12
cells, cultured (12) 12
chemotherapy (12) 12
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


PLoS ONE, ISSN 1932-6203, 2014, Volume 9, Issue 1, pp. e86629 - e86629
Osteoblast apoptosis plays an important role in bone development and maintenance, and is in part responsible for osteoporosis in sex steroid deficiency,... 
TRANSCRIPTION FACTORS | APOPTOSIS | OXIDATIVE STRESS | CELL-CYCLE ENTRY | BONE-FORMATION | MULTIDISCIPLINARY SCIENCES | DNA-DAMAGE | IN-VIVO | PARATHYROID-HORMONE | DEATH | P53 | Up-Regulation | Mice, Inbred C57BL | Forkhead Transcription Factors - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Animals | Forkhead Transcription Factors - metabolism | Gene Deletion | Cell Differentiation | Forkhead Box Protein O1 | Mice | Osteoblasts - cytology | Forkhead Box Protein O3 | Osteoblasts - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Osteogenesis | Apoptosis | Physiological aspects | Corticosteroids | DNA binding proteins | Tumor proteins | Cell culture | Oxidative stress | Transcription factors | Phosphorylation | Glucocorticoids | p53 Protein | Bromodeoxyuridine | AKT protein | Biology | Insulin-like growth factors | Kinases | Inactivation | Osteoblasts | Cell density | Proteins | Osteoporosis | Biomedical materials | Cell growth | FOXO1 protein | Bcl-x protein | Transgenic animals | Rodents | Surgery | Cell cycle | Aging | Forkhead protein | Insulin-like growth factor-binding protein 3 | Biocompatibility | Bones | Physiology | FOXO3 protein | University graduates | Osteocalcin | Deactivation | Gene expression | Insulin | DNA nucleotidylexotransferase | Osteoblastogenesis | Gadd45A protein | FasL protein | Cell death | Differentiation | BIM protein | PTEN protein | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 1, pp. e14500 - e14500
Background: The Gadd45 proteins play important roles in growth control, maintenance of genomic stability, DNA repair, and apoptosis. Recently, Gadd45 proteins... 
U4 SNRNA | RIBOSOMAL-PROTEINS | GLYCOSYLASE | COMPLEX | NEGATIVE GROWTH-CONTROL | CRYSTAL-STRUCTURE | BIOLOGY | CHICKEN-EMBRYO | CELL-CYCLE CHECKPOINTS | DOMAINS | DNA DEMETHYLATION | Xenopus | Cell Line | RNA-Binding Proteins - genetics | RNA-Binding Proteins - physiology | Xenopus Proteins - genetics | Humans | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Ribonucleoproteins - metabolism | Point Mutation | Cell Nucleus Structures - chemistry | DNA Methylation | Animals | Cell Nucleus Structures - ultrastructure | Serine-Arginine Splicing Factors | Xenopus Proteins - physiology | Cell Cycle Proteins - genetics | Protein Binding | Xenopus Proteins - metabolism | Nuclear Proteins - physiology | DEAD-box RNA Helicases - metabolism | Nuclear Proteins - genetics | Cell Cycle Proteins - physiology | RNA-Binding Proteins - metabolism | Epigenetic inheritance | RNA | Gene mutations | DNA | Ribonuclease | Protein binding | Apoptosis | Sucrose | Centrifugation | Gene regulation | Genes | Homology | Amino acids | DNA repair | Molecular weight | Proteins | DNA helicase | Demethylation | Embryology | Cell cycle | Localization | Deoxyribonucleic acid--DNA | Sugars | Immunoglobulins | Statistical analysis | Nucleotide sequence | rRNA | Nucleic acids | Gene expression | RNA-binding protein | Gadd45A protein | Ribonucleic acids | Insects | Ribosomal proteins | Point mutation | GADD45 protein | Control stability | Mutation | RNA helicase | Index Medicus | Deoxyribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, pp. e14060 - e14060
Gemcitabine is a cytotoxic cytidine analog, which is widely used in anti-cancer therapy. One mechanism by which gemcitabine acts is by inhibiting nucleotide... 
EXCISION-REPAIR | METHYLATION | MECHANISM | CISPLATIN | HUMAN-CELLS | BIOLOGY | MISMATCH REPAIR | DRUG-RESISTANCE | CANCER | DAMAGE | 2',2'-DIFLUORODEOXYCYTIDINE | Xenopus | MutL Protein Homolog 1 | Xenopus Proteins - genetics | Humans | Deoxycytidine - pharmacology | HEK293 Cells | Cell Cycle Proteins - genetics | Oocytes - drug effects | Antimetabolites, Antineoplastic - pharmacology | Female | Epigenesis, Genetic - drug effects | Nuclear Proteins - genetics | DNA Repair - drug effects | Oocytes - metabolism | HCT116 Cells | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Gene Expression Regulation - drug effects | Animals | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Xenopus Proteins - metabolism | Adaptor Proteins, Signal Transducing - metabolism | DNA Methylation - drug effects | Deoxycytidine - analogs & derivatives | Epigenetic inheritance | Care and treatment | Gemcitabine | Analysis | Genes | DNA | Genetic engineering | Methylation | Health aspects | DNA repair | Cells | Cancer | Camptothecin | Leukemia | Oct-4 protein | Cytotoxicity | Kinases | Drug resistance | Cancer therapies | Base excision repair | Neurogenesis | Oocytes | Mammalian cells | Proteins | Demethylation | Embryology | Reporter gene | DNA methylation | Inhibition | Repair | Deoxyribonucleic acid--DNA | Enzymes | MLH1 protein | DNA topoisomerase | Polymerization | Nucleotide excision repair | DNA biosynthesis | Gene silencing | Chemotherapy | Gadd45A protein | Plasmids | Epigenetics | GADD45 protein | Tumors | Index Medicus | Deoxyribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2012, Volume 7, Issue 8, pp. e42985 - e42985
P73, one member of the tumor suppressor p53 family, shares highly structural and functional similarity to p53. Like p53, the transcriptionally active TAp73 can... 
SIGNAL-TRANSDUCTION | CARCINOMA-CELLS | APOPTOSIS | PROTEIN | GADD45A | JNK | DNA-DAMAGE | BIOLOGY | STRESS | P73 | P53 | Apoptosis - drug effects | Humans | Gene Expression Regulation, Neoplastic | Apoptosis - genetics | JNK Mitogen-Activated Protein Kinases - metabolism | DNA-Binding Proteins - metabolism | Ovarian Neoplasms - genetics | RNA Interference | Tumor Suppressor Proteins - genetics | Cell Cycle Proteins - genetics | Female | Antineoplastic Agents - pharmacology | Ovarian Neoplasms - metabolism | JNK Mitogen-Activated Protein Kinases - genetics | Nuclear Proteins - genetics | Gene Expression | Tumor Suppressor Proteins - metabolism | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Cisplatin - pharmacology | DNA-Binding Proteins - genetics | Drug Resistance, Neoplasm - genetics | Tumor Protein p73 | Signal Transduction - drug effects | Cell Line, Tumor | Enzyme Activation - genetics | Chemotherapy | Cancer cells | Tumor proteins | Mitogens | Protein kinases | Cisplatin | Cancer | Ovarian cancer | Apoptosis | Transcription factors | Ovarian carcinoma | Bax protein | Transcription | p53 Protein | DNA damage | Kinases | Signal transduction | Inhibition | Deoxyribonucleic acid--DNA | c-Jun protein | MAP kinase | siRNA | Gene expression | Ribonucleic acid--RNA | Signaling | Protein kinase | Tumor suppressor genes | GADD45 protein | Structure-function relationships | Index Medicus | RNA | Deoxyribonucleic acid | Ribonucleic acid | DNA
Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 07/2011, Volume 17, Issue 14, pp. 4650 - 4660
Journal Article
Cancer Letters, ISSN 0304-3835, 08/2018, Volume 430, pp. 34 - 46
Journal Article
International Journal of Hematology, ISSN 0925-5710, 07/2017, Volume 106, Issue 1, pp. 99 - 107
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2012, Volume 287, Issue 33, pp. 27290 - 27301
Diverse stresses including starvation and muscle disuse cause skeletal muscle atrophy. However, the molecular mechanisms of muscle atrophy are complex and not... 
ACTIVATION | PROTEIN | PATHWAY | PGC-1-ALPHA | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | DEGRADATION | GENERATION | FOXO TRANSCRIPTION FACTORS | UBIQUITIN LIGASES | COACTIVATORS | Stress, Physiological | Muscle, Skeletal - metabolism | Proto-Oncogene Proteins c-akt - genetics | RNA, Messenger - biosynthesis | Cell Nucleus - metabolism | Cell Nucleus - pathology | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Muscle Proteins - metabolism | Trans-Activators - genetics | Cell Cycle Proteins - genetics | Protein Biosynthesis - genetics | Energy Metabolism - genetics | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Cell Line | Muscular Atrophy - metabolism | Muscular Atrophy - pathology | RNA, Messenger - genetics | Cell Cycle Proteins - metabolism | Gene Expression Regulation | Activating Transcription Factor 4 - genetics | Muscular Atrophy - genetics | Nuclear Proteins - metabolism | Signal Transduction - genetics | Mice, Knockout | Muscle Proteins - genetics | Animals | Activating Transcription Factor 4 - metabolism | Cell Nucleus - genetics | Trans-Activators - metabolism | Mice | Transcription Factors | Muscle, Skeletal - pathology | Index Medicus | Molecular Bases of Disease | Transcription Regulation | Skeletal Muscle | Skeletal Muscle Metabolism | Stress Response | Gadd45a | Muscle Atrophy | ATF4
Journal Article
Cancer Letters, ISSN 0304-3835, 2012, Volume 329, Issue 2, pp. 217 - 227
Abstract 2′-Benzoyloxycinnamaldehyde (BCA) induces apoptosis in human cancer cells through ROS generation. BCA upregulates proapoptotic genes such as... 
Hematology, Oncology and Palliative Medicine | Prostate cancer cells | Growth arrest and DNA-damage-inducible protein alpha (GADD45A) | Early growth response protein 1 (EGR1) | Activating transcription factor 3 (ATF3) | 2′-Benzoyloxycinnamaldehyde (BCA) | Importin-7 (IPO7) | NSAID-activated gene 1 protein (NAG-1) | 2'-Benzoyloxycinnamaldehyde (BCA) | CARCINOMA-CELLS | APOPTOSIS | OXIDATIVE STRESS | SUPPRESSOR GENE | DNA-DAMAGE | ACTIVATING TRANSCRIPTION FACTOR-3 | CYCLOOXYGENASE INHIBITORS | BETA SUPERFAMILY MEMBER | ONCOLOGY | GENE-EXPRESSION | 2 '-Benzoyloxycinnamaldehyde (BCA) | EGR-1 EXPRESSION | Acrolein - analogs & derivatives | RNA, Small Interfering - genetics | Gene Expression - drug effects | Apoptosis - drug effects | Humans | Male | Growth Differentiation Factor 15 - genetics | Gene Knockdown Techniques | Prostatic Neoplasms | Glutathione - pharmacology | Cell Nucleus - metabolism | Early Growth Response Protein 1 - genetics | Apoptosis Regulatory Proteins - genetics | Cell Cycle Proteins - genetics | Antineoplastic Agents - pharmacology | Active Transport, Cell Nucleus | Nuclear Proteins - genetics | Activating Transcription Factor 3 - genetics | Acrolein - pharmacology | Cell Survival - drug effects | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Antioxidants - pharmacology | Activating Transcription Factor 3 - metabolism | Apoptosis Regulatory Proteins - metabolism | Up-Regulation - drug effects | Karyopherins - metabolism | Benzoates - pharmacology | Cell Line, Tumor | Karyopherins - genetics | Cell Nucleus - drug effects | Growth Differentiation Factor 15 - metabolism | Early Growth Response Protein 1 - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Antioxidants | Anopheles | Growth | Cell death | Genes | Biochemistry | Genetic transcription | Cell growth | Prostate cancer | Rodents | Apoptosis | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, pp. e83133 - e83133
Glomerular podocyte cells are critical for the function of the renal ultrafiltration barrier. Especially, the highly specialized cell cell junction of... 
NEPHROTIC SYNDROME | NEPHRIN | PODOCYTE | EXPRESSION | MULTIDISCIPLINARY SCIENCES | MOUSE | Podocytes - metabolism | Nerve Tissue Proteins - deficiency | Cell Cycle Proteins - metabolism | Male | Nuclear Proteins - metabolism | Glomerular Filtration Rate - physiology | Nerve Tissue Proteins - genetics | Mice, Knockout | Protein Transport | Morphogenesis | Podocytes - cytology | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Cell Nucleus - metabolism | Gene Expression Regulation, Developmental | Kidney Glomerulus - growth & development | Cell Cycle Proteins - genetics | Kidney Glomerulus - metabolism | Protein Binding | Female | Mice | Nuclear Proteins - genetics | Kidney Glomerulus - cytology | Genetic transcription | Kidney diseases | Genes | Protein binding | Immunoprecipitation | Yeast | Renal function | Transcription | DNA damage | Biology | Biochemistry | Nuclei | Proteins | Immunology | Ultrafiltration | CD2-associated protein | Rodents | Diaphragm (anatomy) | Relocation | Deoxyribonucleic acid--DNA | Kidneys | Filtration | Molecular interactions | Histology | Biophysics | Gene expression | Medical screening | Studies | Gadd45A protein | Nephropathy | Life span | Diaphragm | Mutation | Proteinuria | Kidney transplantation | Apoptosis | Index Medicus | Medical and Health Sciences | Medicin och hälsovetenskap | Deoxyribonucleic acid | DNA
Journal Article