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1. Full Text 2015 Update on Acute Adverse Reactions to Gadolinium based Contrast Agents in Cardiovascular MR. Large Multi-National and Multi-Ethnical Population Experience With 37788 Patients From the EuroCMR Registry
by Bruder, O and Schneider, S and Pilz, G and van Rossum, A.C and Schwitter, J and Nothnagel, D and Lombardi, M and Buss, S and Wagner, A and Petersen, S and Greulich, S and Jensen, C and Nagel, E and Sechtem, U and Mahrholdt, H
Journal of cardiovascular magnetic resonance, ISSN 1097-6647, 2015, Volume 17, Issue 1, pp. 58 - 58
Gadolinium | "Off-label use" | Safety | Cardiovascular magnetic resonance | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Severity of Illness Index | Acute Disease | Risk Assessment | Adverse Drug Reaction Reporting Systems | Humans | Magnetic Resonance Imaging - adverse effects | Risk Factors | Drug-Related Side Effects and Adverse Reactions - ethnology | Europe - epidemiology | Gadolinium - adverse effects | Dose-Response Relationship, Drug | Contrast Media - adverse effects | Patient Safety | Registries | Drug-Related Side Effects and Adverse Reactions - diagnosis | Cardiovascular Diseases - diagnosis | Complications and side effects | Surface active agents | Contrast media | Index Medicus
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2. Full Text Histology and Gadolinium Distribution in the Rodent Brain After the Administration of Cumulative High Doses of Linear and Macrocyclic Gadolinium-Based Contrast Agents
by Lohrke, Jessica and Frisk, Anna-Lena and Frenzel, Thomas and Schöckel, Laura and Rosenbruch, Martin and Jost, Gregor and Lenhard, Diana Constanze and Sieber, Martin A and Nischwitz, Volker and Küppers, Astrid and Pietsch, Hubertus
Investigative radiology, ISSN 0020-9996, 03/2017, Volume 52, Issue 6, pp. 324 - 333
Gadodiamide | Gadobutrol | Gadolinium retention | MRI | Contrast agent | Gadoteridol | Globus pallidus | Histology | Dentate nucleus | Gadopentetate dimeglumine | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Gadolinium - administration & dosage | Injections, Intravenous | Rats, Wistar | Gadolinium - pharmacokinetics | Contrast Media - pharmacokinetics | Male | Muscle, Skeletal - metabolism | Bone and Bones - drug effects | Brain - metabolism | Dose-Response Relationship, Drug | Contrast Media - adverse effects | Bone and Bones - metabolism | Contrast Media - administration & dosage | Mass Spectrometry | Muscle, Skeletal - drug effects | Brain - ultrastructure | Gadolinium DTPA - pharmacokinetics | Models, Animal | Gadolinium DTPA - administration & dosage | Retrospective Studies | Gadolinium DTPA - adverse effects | Heterocyclic Compounds - administration & dosage | Organometallic Compounds - adverse effects | Rodentia | Organometallic Compounds - pharmacokinetics | Rats | Gadolinium - adverse effects | Brain - drug effects | Animals | Heterocyclic Compounds - adverse effects | Skin - ultrastructure | Heterocyclic Compounds - pharmacokinetics | Skin - drug effects | Organometallic Compounds - administration & dosage | Index Medicus | gadolinium retention | histology | gadopentetate dimeglumine | gadobutrol | Original | globus pallidus | gadoteridol | contrast agent | dentate nucleus | gadodiamide
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3. Full Text A Structured Survey on Adverse Events Occurring Within 24 Hours After Intravenous Exposure to Gadodiamide or Gadoterate Meglumine: A Controlled Prospective Comparison Study
by Parillo, Marco and Sapienza, Martina and Arpaia, Francesco and Magnani, Francesca and Mallio, Carlo Augusto and DʼAlessio, Pasquale and Quattrocchi, Carlo Cosimo
Investigative radiology, ISSN 0020-9996, 04/2019, Volume 54, Issue 4, pp. 191 - 197
magnetic resonance imaging | adverse events | adverse drug reaction | contrast media | gadolinium | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Gadolinium DTPA - adverse effects | Prospective Studies | Organometallic Compounds - adverse effects | Humans | Middle Aged | Magnetic Resonance Imaging - methods | Male | Surveys and Questionnaires - statistics & numerical data | Incidence | Young Adult | Administration, Intravenous | Contrast Media - adverse effects | Contrast Media - administration & dosage | Meglumine - administration & dosage | Adolescent | Aged, 80 and over | Adult | Female | Aged | Gadolinium DTPA - administration & dosage | Image Enhancement - methods | Meglumine - adverse effects | Cohort Studies | Organometallic Compounds - administration & dosage | Drugs | Adverse and side effects | Diagnosis | Index Medicus
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4. Full Text Patient Safety Issues in CKD: Core Curriculum 2015
by Wagner, Lee-Ann, MD and Tata, Asha L., PharmD, BCPS and Fink, Jeffrey C., MD, MS
American journal of kidney diseases, ISSN 0272-6386, 2015, Volume 66, Issue 1, pp. 159 - 169
Nephrology | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Humans | Pain Management | Diabetic Nephropathies - drug therapy | Metabolic Clearance Rate | Analgesics - pharmacokinetics | Renal Insufficiency, Chronic - complications | Renal Insufficiency, Chronic - metabolism | Anti-Bacterial Agents - therapeutic use | Bacterial Infections - complications | Renal Insufficiency, Chronic - therapy | Anemia - drug therapy | Contrast Media - adverse effects | Drug Interactions | Patient Safety | Acute Kidney Injury - chemically induced | Anti-Bacterial Agents - adverse effects | Platelet Aggregation Inhibitors - pharmacokinetics | Platelet Aggregation Inhibitors - therapeutic use | Anemia - etiology | Kidney - physiopathology | Analgesics - adverse effects | Platelet Aggregation Inhibitors - adverse effects | Hypoglycemic Agents - therapeutic use | Medication Errors | Analgesics - therapeutic use | Arrhythmias, Cardiac - prevention & control | Hyperkalemia - complications | Hypoglycemic Agents - pharmacokinetics | Glomerular Filtration Rate | Hematinics - therapeutic use | Bacterial Infections - drug therapy | Hyperkalemia - physiopathology | Anticoagulants - therapeutic use | Hematinics - adverse effects | Renin-Angiotensin System - physiology | Arrhythmias, Cardiac - etiology | Gadolinium - adverse effects | Anticoagulants - adverse effects | Hyperkalemia - chemically induced | Renin-Angiotensin System - drug effects | Aged | Anticoagulants - pharmacokinetics | Iodine Compounds - adverse effects | Pharmacokinetics | Insulin - adverse effects | Insulin - therapeutic use | Index Medicus
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5. Full Text Gadolinium deposition disease: Initial description of a disease that has been around for a while
by Semelka, Richard C and Ramalho, Joana and Vakharia, Ami and AlObaidy, Mamdoh and Burke, Lauren M and Jay, Michael and Ramalho, Miguel
Magnetic resonance imaging, ISSN 0730-725X, 2016, Volume 34, Issue 10, pp. 1383 - 1390
Radiology | Gadolinium deposition disease | NSF | Survey | Gadolinium toxicity | Gadolinium based contrast agents | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Gadolinium DTPA - adverse effects | Prospective Studies | Organometallic Compounds - adverse effects | Humans | Meglumine - urine | Middle Aged | Male | Gadolinium - adverse effects | Pain - chemically induced | Meglumine - analogs & derivatives | Gadolinium - urine | Magnetic Resonance Imaging | Contrast Media - adverse effects | Heterocyclic Compounds - adverse effects | Adult | Female | Aged | Gadolinium DTPA - urine | Heterocyclic Compounds - urine | Organometallic Compounds - urine | Meglumine - adverse effects | Gadolinium | Index Medicus
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6. Full Text Critical questions regarding gadolinium deposition in the brain and body after injections of the gadolinium-based contrast agents, safety, and clinical recommendations in consideration of the EMA's pharmacovigilance and risk assessment committee recommendation for suspension of the marketing authorizations for 4 linear agents
by Runge, Val M
Investigative radiology, ISSN 0020-9996, 2017, Volume 52, Issue 6, pp. 317 - 323
Gadodiamide | Gadobenate dimeglumine | Gadoversetamide | Magnetic resonance | Gadolinium | Gadolinium-based contrast agents | Safety | Dentate nucleus | Gadopentetate dimeglumine | Contrast media | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Injections, Intravenous | Gadolinium - pharmacokinetics | Humans | Contrast Media - pharmacokinetics | Muscle, Skeletal - metabolism | Bone and Bones - drug effects | Brain - metabolism | Contrast Media - adverse effects | Bone and Bones - metabolism | Muscle, Skeletal - drug effects | Gadolinium DTPA - pharmacokinetics | Marketing - legislation & jurisprudence | Meglumine - adverse effects | Gadolinium DTPA - adverse effects | Risk Assessment | Organometallic Compounds - adverse effects | Europe | Organometallic Compounds - pharmacokinetics | Gadolinium - adverse effects | Pharmacovigilance | Meglumine - analogs & derivatives | Brain - drug effects | Magnetic Resonance Imaging | Animals | Meglumine - pharmacokinetics | Practice Guidelines as Topic | Index Medicus
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7. Full Text Safety and adverse effects during 24 hours after contrast-enhanced MRI with gadobenate dimeglumine (MultiHance®) in children
by Schneider, Guenther and Schneider, Guenther and Schürholz, Hellmut and Schürholz, Hellmut and Kirchin, Miles A and Kirchin, Miles A and Bücker, Arno and Bücker, Arno and Fries, Peter and Fries, Peter
Pediatric radiology, ISSN 0301-0449, 2/2013, Volume 43, Issue 2, pp. 202 - 211
Pediatrics | Medicine & Public Health | Magnetic resonance imaging | MRI | Gadobenate dimeglumine | Oncology | Nuclear Medicine | Safety | Imaging / Radiology | Ultrasound | Neuroradiology | Contrast media | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Prevalence | Humans | Risk Factors | Child, Preschool | Infant | Male | Drug-Related Side Effects and Adverse Reactions - epidemiology | Germany - epidemiology | Meglumine - analogs & derivatives | Organometallic Compounds | Contrast Media | Magnetic Resonance Imaging - statistics & numerical data | Adolescent | Female | Child | Infant, Newborn | Complications and side effects | Usage | Dosage and administration | Methods | Safety and security measures | Fibrosis | Gadolinium | Diagnosis | Index Medicus
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8. Are gadolinium-based contrast media really safer than iodinated media for digital subtraction angiography in patients with azotemia?
by Nyman, Ulf and Elmståhl, Barbara and Leander, Peter and Nilsson, Mats and Golman, Klaes and Almén, Torsten
Radiology, ISSN 0033-8419, 2002, Volume 223, Issue 2, pp. 311 - 318
Contrast media, toxicity | Iodine and iodine compounds | Angiography, contrast media | Contrast media, effects | Gadolinium | Contrast media, complications | Uremia | Life Sciences & Biomedicine | Radiology, Nuclear Medicine & Medical Imaging | Science & Technology | Gadolinium DTPA - adverse effects | Humans | Chelating Agents - chemistry | Uremia - complications | Angiography, Digital Subtraction | Radiology, Interventional | Contrast Media - adverse effects | Kidney Diseases - chemically induced | Contrast Media - chemistry | Triiodobenzoic Acids - adverse effects | Triiodobenzoic Acids - chemistry | Gadolinium DTPA - chemistry | Chelating Agents - adverse effects | Index Medicus | Abridged Index Medicus
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9. Full Text Zero-inflated Poisson model based likelihood ratio test for drug safety signal detection
by Huang, Lan and Zheng, Dan and Zalkikar, Jyoti and Tiwari, Ram
Statistical methods in medical research, ISSN 0962-2802, 2/2017, Volume 26, Issue 1, pp. 471 - 488
adverse event reporting system database | likelihood ratio test | expectation and maximization algorithm | false discovery rate | type I error | Statistics & Probability | Physical Sciences | Life Sciences & Biomedicine | Medical Informatics | Health Care Sciences & Services | Mathematics | Science & Technology | Mathematical & Computational Biology | Gadolinium DTPA - adverse effects | Prednisone - adverse effects | Adverse Drug Reaction Reporting Systems | Organometallic Compounds - adverse effects | United States | Humans | Data Mining | Male | Heparin - adverse effects | Fatty Alcohols - adverse effects | United States Food and Drug Administration - legislation & jurisprudence | Meglumine - analogs & derivatives | Likelihood Functions | Algorithms | Aspirin - adverse effects | Female | Poisson Distribution | Research Design | Meglumine - adverse effects | Databases, Factual | Regulatory agencies | Parameter estimation | Transportation safety | Statistical methods | Data mining | Mining | Databases | Data base management systems | Matrices | Adverse | Safety | Signals | Maximum likelihood estimates | Product safety | Signal detection | Parameters | Computer simulation | Test procedures | Critical incidents | Discovery | Likelihood ratio | Reporting | Simulation | Normal distribution | Detection | Bayesian analysis | Pharmaceuticals | Index Medicus | Drugs | Counting
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10. Full Text Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis
by Hauser, Stephen L and Bar-Or, Amit and Comi, Giancarlo and Giovannoni, Gavin and Hartung, Hans-Peter and Hemmer, Bernhard and Lublin, Fred and Montalban, Xavier and Rammohan, Kottil W and Selmaj, Krzysztof and Traboulsee, Anthony and Wolinsky, Jerry S and Arnold, Douglas L and Klingelschmitt, Gaelle and Masterman, Donna and Fontoura, Paulo and Belachew, Shibeshih and Chin, Peter and Mairon, Nicole and Garren, Hideki and Kappos, Ludwig and OPERA I OPERA II Clinical and OPERA I and OPERA II Clinical Investigators
The New England journal of medicine, ISSN 0028-4793, 01/2017, Volume 376, Issue 3, pp. 221 - 234
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Antibodies, Monoclonal, Humanized - adverse effects | Recurrence | Brain - diagnostic imaging | Antibodies, Monoclonal, Humanized - therapeutic use | Antigens, CD20 | Multiple Sclerosis, Relapsing-Remitting - drug therapy | Humans | Middle Aged | Male | Disease Progression | Interferon-beta - therapeutic use | Magnetic Resonance Imaging | B-Lymphocytes - immunology | Interferon-beta - adverse effects | Multiple Sclerosis, Relapsing-Remitting - diagnostic imaging | Infusions, Intravenous - adverse effects | Adult | Female | Immunologic Factors - adverse effects | Immunologic Factors - therapeutic use | Multiple sclerosis | Intravenous administration | Lymphocytes B | Lymphocytes | β-Interferon | Immunotherapy | Clinical trials | Monoclonal antibodies | CD20 antigen | Gadolinium | Cognition | Interferon | Index Medicus | Abridged Index Medicus | Medicin och hälsovetenskap
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