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1. Full Text Frequency and Severity of Adverse Effects of Iodinated and Gadolinium Contrast Materials: Retrospective Review of 456,930 Doses
by Hunt, Christopher H and Hartman, Robert P and Hesley, Gina K
American Journal of Roentgenology, ISSN 0361-803X, 10/2009, Volume 193, Issue 4, pp. 1124 - 1127
OBJECTIVE. The purpose of this study was to determine the frequency and characteristics of adverse effects of low-osmolar iodinated and gadolinium contrast... 
Iodinated contrast | Contrast reactions | Gadolinium | PRETREATMENT | SAFETY | iodinated contrast | MEDIA | CORTICOSTEROIDS | contrast reactions | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | gadolinium | Risk Assessment | Humans | Middle Aged | Risk Factors | Male | Survival Rate | Incidence | Minnesota - epidemiology | Young Adult | Adolescent | Survival Analysis | Aged, 80 and over | Adult | Female | Aged | Retrospective Studies | Drug-Related Side Effects and Adverse Reactions - mortality | Child | Iodine | Index Medicus | Abridged Index Medicus
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2. Full Text Adverse Effects of Gadolinium-Based Contrast Agents: Changes in Practice Patterns
by Forghani, Reza
Topics in Magnetic Resonance Imaging, ISSN 0899-3459, 08/2016, Volume 25, Issue 4, pp. 163 - 169
ABSTRACTGadolinium-based contrast agents have been used for magnetic resonance imaging (MRI) examinations since the late 1980s with an excellent overall... 
gadolinium-based contrast agents | gadolinium brain deposition | nephrogenic systemic fibrosis | gadolinium | Practice Patterns, Physicians' - trends | Gadolinium - adverse effects | Contrast Media - adverse effects | Magnetic Resonance Imaging - standards | Humans
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3. Full Text Safety and adverse effects during 24 hours after contrast-enhanced MRI with gadobenate dimeglumine (MultiHance®) in children
by Schneider, Guenther and Schneider, Guenther and Schürholz, Hellmut and Schürholz, Hellmut and Kirchin, Miles A and Kirchin, Miles A and Bücker, Arno and Bücker, Arno and Fries, Peter and Fries, Peter
Pediatric Radiology, ISSN 0301-0449, 2/2013, Volume 43, Issue 2, pp. 202 - 211
Gadolinium-based MR contrast agents have long been considered safe for routine diagnostic imaging. However, the advent of nephrogenic systemic fibrosis (NSF)... 
Pediatrics | Medicine & Public Health | Magnetic resonance imaging | MRI | Gadobenate dimeglumine | Oncology | Nuclear Medicine | Safety | Imaging / Radiology | Ultrasound | Neuroradiology | Contrast media | GADOLINIUM | GADOPENTETATE DIMEGLUMINE | GADOVERSETAMIDE INJECTION OPTIMARK | LIVER PATHOLOGY | CLINICAL SAFETY | DOUBLE-BLIND | PEDIATRICS | CENTRAL-NERVOUS-SYSTEM | FOCAL NODULAR HYPERPLASIA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | NEPHROGENIC SYSTEMIC FIBROSIS | MAGNETIC-RESONANCE ANGIOGRAPHY | Prevalence | Humans | Risk Factors | Child, Preschool | Infant | Male | Drug-Related Side Effects and Adverse Reactions - epidemiology | Germany - epidemiology | Meglumine - analogs & derivatives | Organometallic Compounds | Contrast Media | Magnetic Resonance Imaging - statistics & numerical data | Adolescent | Female | Child | Infant, Newborn | Complications and side effects | Usage | Dosage and administration | Methods | Safety and security measures | Fibrosis | Gadolinium | Diagnosis
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4. Full Text Investigation of adverse effect of coexisting aminopolycarboxylates on the determination of rare earth elements by ICP-MS after solid phase extraction using an iminodiacetate-based chelating-resin
by Fujimori, Eiji and Nagata, Suzuka and Kumata, Hidetoshi and Umemura, Tomonari
Chemosphere, ISSN 0045-6535, 01/2019, Volume 214, pp. 288 - 294
When iminodiacetic acid chelating-resin solid phase extraction (SPE) was used for the preconcentration of rare earth elements (REEs) in river water samples... 
Chelating-resin solid phase extraction | Sewage treatment plant effluent | ICP-MS | Rare earth elements | EDTA | TOKYO | RIVER WATERS | COAL | SEAWATER | GADOLINIUM ANOMALIES | ENVIRONMENTAL SCIENCES | SPECIATION | BAY | Hydrogen Peroxide - chemistry | Reproducibility of Results | Edetic Acid - chemistry | Mass Spectrometry | Solid Phase Extraction | Fresh Water - chemistry | Calcium Chelating Agents - chemistry | Spectrum Analysis | Metals, Rare Earth - analysis | Rare earth metals | Ethylenediaminetetraacetic acid | Complications and side effects | Usage | Sewage | Purification | Adsorption | Analysis | Investigations
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5. Full Text Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis
by Hauser, Stephen L and Bar-Or, Amit and Comi, Giancarlo and Giovannoni, Gavin and Hartung, Hans-Peter and Hemmer, Bernhard and Lublin, Fred and Montalban, Xavier and Rammohan, Kottil W and Selmaj, Krzysztof and Traboulsee, Anthony and Wolinsky, Jerry S and Arnold, Douglas L and Klingelschmitt, Gaelle and Masterman, Donna and Fontoura, Paulo and Belachew, Shibeshih and Chin, Peter and Mairon, Nicole and Garren, Hideki and Kappos, Ludwig and OPERA I OPERA II Clinical and OPERA I and OPERA II Clinical Investigators
The New England Journal of Medicine, ISSN 0028-4793, 01/2017, Volume 376, Issue 3, pp. 221 - 234
In two trials involving patients with relapsing multiple sclerosis, the anti-CD20+ monoclonal antibody ocrelizumab was associated with lower annualized relapse... 
TRIAL | MEDICINE, GENERAL & INTERNAL | ANTIBODIES TARGETING CD20 | DEMYELINATION | RITUXIMAB | B-CELL DEPLETION | DISEASE | CANCER-RISK | DISABILITY | PATHOLOGY | PROSPECTS | Antibodies, Monoclonal, Humanized - adverse effects | Recurrence | Brain - diagnostic imaging | Antibodies, Monoclonal, Humanized - therapeutic use | Antigens, CD20 | Multiple Sclerosis, Relapsing-Remitting - drug therapy | Humans | Middle Aged | Male | Disease Progression | Interferon-beta - therapeutic use | Magnetic Resonance Imaging | B-Lymphocytes - immunology | Interferon-beta - adverse effects | Multiple Sclerosis, Relapsing-Remitting - diagnostic imaging | Infusions, Intravenous - adverse effects | Adult | Female | Immunologic Factors - adverse effects | Immunologic Factors - therapeutic use | Multiple sclerosis | Intravenous administration | Lymphocytes B | Lymphocytes | β-Interferon | Immunotherapy | Clinical trials | Monoclonal antibodies | CD20 antigen | Gadolinium | Cognition | Interferon
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6. Full Text 2015 Update on Acute Adverse Reactions to Gadolinium based Contrast Agents in Cardiovascular MR. Large Multi-National and Multi-Ethnical Population Experience With 37788 Patients From the EuroCMR Registry
by Bruder, O and Schneider, S and Pilz, G and van Rossum, A.C and Schwitter, J and Nothnagel, D and Lombardi, M and Buss, S and Wagner, A and Petersen, S and Greulich, S and Jensen, C and Nagel, E and Sechtem, U and Mahrholdt, H
Journal of Cardiovascular Magnetic Resonance, ISSN 1097-6647, 2015, Volume 17, Issue 1, p. 58
Objectives: Specifically we aim to demonstrate that the results of our earlier safety data hold true in this much larger multi-national and multi-ethnical... 
Gadolinium | "Off-label use" | Safety | Cardiovascular magnetic resonance | CARDIAC & CARDIOVASCULAR SYSTEMS | FREQUENCY | MAGNETIC-RESONANCE | MEDIA | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | SEVERITY | Severity of Illness Index | Acute Disease | Risk Assessment | Adverse Drug Reaction Reporting Systems | Humans | Magnetic Resonance Imaging - adverse effects | Risk Factors | Drug-Related Side Effects and Adverse Reactions - ethnology | Europe - epidemiology | Gadolinium - adverse effects | Dose-Response Relationship, Drug | Contrast Media - adverse effects | Patient Safety | Registries | Drug-Related Side Effects and Adverse Reactions - diagnosis | Cardiovascular Diseases - diagnosis | Complications and side effects | Surface active agents | Contrast media
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7. Nephrogenic systemic fibrosis: Risk factors and incidence estimation
by Sadowski, Elizabeth A and Bennett, Lindsey K and Chan, Micah R and Wentland, Andrew L and Garrett, Andrea L and Garrett, Robert W and Djamali, Arjang
Radiology, ISSN 0033-8419, 04/2007, Volume 243, Issue 1, pp. 148 - 157
Purpose: To retrospectively review data in 13 patients with biopsy-confirmed nephrogenic systemic fibrosis (NSF), assess the associated risk factors, and... 
DERMOPATHY | GADOLINIUM | MEDIA | CONTRAST AGENTS | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | INVOLVEMENT | Skin Diseases - chemically induced | Gadolinium DTPA - adverse effects | Glomerular Filtration Rate | Organometallic Compounds - adverse effects | Humans | Magnetic Resonance Imaging - adverse effects | Middle Aged | Risk Factors | Logistic Models | Male | Meglumine - analogs & derivatives | Contrast Media - adverse effects | Adolescent | Fibrosis | Adult | Female | Renal Insufficiency - complications | Aged | Retrospective Studies | Meglumine - adverse effects | Skin - pathology
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8. Full Text Histology and Gadolinium Distribution in the Rodent Brain After the Administration of Cumulative High Doses of Linear and Macrocyclic Gadolinium-Based Contrast Agents
by Lohrke, Jessica and Frisk, Anna-Lena and Frenzel, Thomas and Schöckel, Laura and Rosenbruch, Martin and Jost, Gregor and Lenhard, Diana Constanze and Sieber, Martin A and Nischwitz, Volker and Küppers, Astrid and Pietsch, Hubertus
Investigative Radiology, ISSN 0020-9996, 03/2017, Volume 52, Issue 6, pp. 324 - 333
OBJECTIVESRetrospective studies in patients with primary brain tumors or other central nervous system pathologies as well as postmortem studies have suggested... 
Gadodiamide | Gadobutrol | Gadolinium retention | MRI | Contrast agent | Gadoteridol | Globus pallidus | Histology | Dentate nucleus | Gadopentetate dimeglumine | HEALTHY RATS DIFFERENCE | HIGH-SIGNAL INTENSITY | GLOBUS-PALLIDUS | RENAL-FUNCTION | gadoteridol | contrast agent | dentate nucleus | DEEP CEREBELLAR NUCLEI | gadodiamide | gadolinium retention | T1-WEIGHTED MR-IMAGES | histology | gadopentetate dimeglumine | gadobutrol | ENHANCED MRI | globus pallidus | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | NEPHROGENIC SYSTEMIC FIBROSIS | Gadolinium - administration & dosage | Injections, Intravenous | Rats, Wistar | Gadolinium - pharmacokinetics | Contrast Media - pharmacokinetics | Male | Muscle, Skeletal - metabolism | Bone and Bones - drug effects | Brain - metabolism | Dose-Response Relationship, Drug | Contrast Media - adverse effects | Bone and Bones - metabolism | Contrast Media - administration & dosage | Mass Spectrometry | Muscle, Skeletal - drug effects | Brain - ultrastructure | Gadolinium DTPA - pharmacokinetics | Models, Animal | Gadolinium DTPA - administration & dosage | Retrospective Studies | Gadolinium DTPA - adverse effects | Heterocyclic Compounds - administration & dosage | Organometallic Compounds - adverse effects | Rodentia | Organometallic Compounds - pharmacokinetics | Rats | Gadolinium - adverse effects | Brain - drug effects | Animals | Heterocyclic Compounds - adverse effects | Skin - ultrastructure | Heterocyclic Compounds - pharmacokinetics | Skin - drug effects | Organometallic Compounds - administration & dosage | Original
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9. Full Text Gadolinium deposition disease: initial description of a disease that has been around for a while
by Semelka, Richard C and Ramalho, Joana and Vakharia, Ami and AlObaidy, Mamdoh and Brubaker, Lauren M and Jay, Michael and Ramalho, Miguel
Magnetic Resonance Imaging, ISSN 0730-725X, 2016, Volume 34, Issue 10, pp. 1383 - 1390
Abstract Purpose To describe the clinical manifestations of presumed gadolinium toxicity in patients with normal renal function. Materials and Methods... 
Radiology | Gadolinium deposition disease | NSF | Survey | Gadolinium toxicity | Gadolinium based contrast agents | CONTRAST AGENTS | SKIN | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | NEPHROGENIC SYSTEMIC FIBROSIS | Gadolinium DTPA - adverse effects | Prospective Studies | Organometallic Compounds - adverse effects | Humans | Meglumine - urine | Middle Aged | Male | Gadolinium - adverse effects | Pain - chemically induced | Meglumine - analogs & derivatives | Gadolinium - urine | Magnetic Resonance Imaging | Contrast Media - adverse effects | Heterocyclic Compounds - adverse effects | Adult | Female | Aged | Gadolinium DTPA - urine | Heterocyclic Compounds - urine | Organometallic Compounds - urine | Meglumine - adverse effects | Gadolinium | Index Medicus
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10. Full Text Perfusion MRI: The five most frequently asked technical questions
by Essig, Marco and Shiroishi, Mark S and Nguyen, Thanh Binh and Saake, Marc and Provenzale, James M and Enterline, David and Anzalone, Nicoletta and Dor̈fler, Arnd and Rovira, Àlex and Wintermark, Max and Law, Meng
American Journal of Roentgenology, ISSN 0361-803X, 01/2013, Volume 200, Issue 1, pp. 24 - 34
OBJECTIVE. This and its companion article address the 10 most frequently asked questions that radiologists face when planning, performing, processing, and... 
Contrast agents | Perfusion MRI | Gadobutrol | CNS imaging | perfusion MRI | CONTRAST-ENHANCED MRI | GADOPENTETATE DIMEGLUMINE | ARTERIAL-BLOOD VOLUME | contrast agents | NONINVASIVE MEASUREMENT | BRAIN-TUMORS | DIAGNOSTIC-ACCURACY | ACUTE ADVERSE-REACTIONS | BOOKEND T-1 MEASUREMENTS | gadobutrol | MAGNETIC-RESONANCE PERFUSION | GADOBENATE DIMEGLUMINE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Brain - blood supply | Gadolinium DTPA - adverse effects | Contrast Media - adverse effects | Injections, Intravenous | Brain Diseases - diagnosis | Organometallic Compounds - adverse effects | Contrast Media - administration & dosage | Humans | Gadolinium | Magnetic Resonance Angiography - methods | Magnetic Resonance Angiography - adverse effects
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11. Full Text Intravenous Imaging Contrast Media Complications: The Basics That Every Clinician Needs to Know
by Rose, Trevor A., MD, MPH and Choi, Jung W., MD, PhD
American Journal of Medicine, The, ISSN 0002-9343, 2015, Volume 128, Issue 9, pp. 943 - 949
Abstract Intravenous contrast is commonly used in noninvasive imaging procedures such as magnetic resonance imaging and computed tomography and can evaluate... 
Internal Medicine | Nephrogenic | Allergy | Nephropathy | Complications | Intravenous | Extravasation | Fibrosis | Gadolinium | Systemic | Metformin | Contrast | Induced | SODIUM-BICARBONATE | METAANALYSIS | INDUCED NEPHROPATHY | PREVENTION | ADVERSE-REACTIONS | MEDICINE, GENERAL & INTERNAL | INCREASED RISK | ELEVATED SERUM CREATININE | INDUCED NEPHROTOXICITY | TRAUMA PATIENTS | NEPHROGENIC SYSTEMIC FIBROSIS | Gadolinium - administration & dosage | Injections, Intravenous | Fibrosis - chemically induced | Kidney - pathology | Humans | Radioisotopes - adverse effects | Hypersensitivity, Immediate - chemically induced | Gadolinium - adverse effects | Metformin - adverse effects | Iodine Radioisotopes - adverse effects | Iodine Radioisotopes - administration & dosage | Contrast Media - adverse effects | Contrast Media - administration & dosage | Kidney Diseases - chemically induced | Radioisotopes - administration & dosage | Extravasation of Diagnostic and Therapeutic Materials - etiology | Hypoglycemic Agents - adverse effects | Diagnostic imaging | Contrast media | Index Medicus | Abridged Index Medicus
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12. Full Text Incidence of immediate gadolinium contrast media reactions
by Prince, Martin R and Zhang, Honglei and Zou, Zhitong and Staron, Ronald B and Brill, Paula W
American Journal of Roentgenology, ISSN 0361-803X, 02/2011, Volume 196, Issue 2, pp. W138 - W143
OBJECTIVE. Our objective was to determine the incidence of immediate adverse events for gadolinium-based contrast agents. MATERIALS AND METHODS. All... 
Gadodiamide | Gadolinium | Nephrogenic systemic fibrosis | Anaphylactoid reactions | Gadobenate dimeglumine | MRI | GADOPENTETATE DIMEGLUMINE | nephrogenic systemic fibrosis | RISK | RELEASE | ADVERSE-REACTIONS | gadodiamide | AGENT | CLINICAL SAFETY | anaphylactoid reactions | ADMINISTRATIONS | gadobenate dimeglumine | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | gadolinium | United States - epidemiology | Humans | Middle Aged | Child, Preschool | Infant | Male | Cause of Death | Incidence | Young Adult | Contrast Media - adverse effects | Anaphylaxis - chemically induced | Aged, 80 and over | Adult | Female | Retrospective Studies | Child | Nephrogenic Fibrosing Dermopathy - epidemiology | Meglumine - adverse effects | Drug Hypersensitivity - etiology | Gadolinium DTPA - adverse effects | Organometallic Compounds - adverse effects | Nephrogenic Fibrosing Dermopathy - chemically induced | Gadolinium - adverse effects | Meglumine - analogs & derivatives | Magnetic Resonance Imaging | Drug Hypersensitivity - epidemiology | Adolescent | Anaphylaxis - diagnosis | Aged | Anaphylaxis - epidemiology | Nephrogenic Fibrosing Dermopathy - diagnosis
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13. Full Text Nephrogenic systemic fibrosis: a serious late adverse reaction to gadodiamide
by Thomsen, Henrik S
European Radiology, ISSN 0938-7994, 12/2006, Volume 16, Issue 12, pp. 2619 - 2621
Medicine & Public Health | Diagnostic Radiology | Internal Medicine | Interventional Radiology | Imaging / Radiology | Ultrasound | Neuroradiology | DERMOPATHY | GADOLINIUM | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | Magnetic Resonance Imaging | Skin Diseases - chemically induced | Gadolinium DTPA - adverse effects | Contrast Media - adverse effects | Kidney - drug effects | Fibrosis - chemically induced | Kidney - pathology | Humans | Kidney Failure, Chronic - complications | Skin Diseases - pathology | Disease Progression
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