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Toxicology and Applied Pharmacology, ISSN 0041-008X, 04/2012, Volume 260, Issue 1, pp. 35 - 47
Mangiferin, a xanthone glucoside, is well known to exhibit antioxidant, antiviral, antitumor, anti-inflammatory and gene-regulatory effects. In the present... 
Hepatic nitrosative stress | Reactive oxygen species | TNFα | Cell survival | NFκB | d-galactosamine | Nrf2 | Apoptosis and necrosis | iNOS | Antioxidant | Caspase-3 | Mangiferin | D-galactosamine | INOS | TNF alpha | PRIMARY CULTURE | RAT HEPATOCYTES | INDUCED LIVER-INJURY | CAJANUS-INDICUS L | CELL-DEATH | NATURALLY-OCCURRING GLUCOSYLXANTHONE | INDUCIBLE NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | TOXICOLOGY | TNF-ALPHA | NF-KAPPA-B | NF kappa B | INDUCED HEPATOTOXICITY | Mangifera - chemistry | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Antioxidants - metabolism | Hepatocytes - pathology | Male | NF-kappa B - metabolism | RNA, Messenger - metabolism | Xanthones - pharmacology | Hepatocytes - drug effects | Disease Models, Animal | Xanthones - isolation & purification | Liver Diseases - prevention & control | Rats | Antioxidants - pharmacology | Gene Expression Regulation - drug effects | Animals | Signal Transduction - drug effects | Antioxidants - isolation & purification | NF-E2-Related Factor 2 - metabolism | Inflammation - prevention & control | Liver Diseases - physiopathology | Oxidative Stress - drug effects | Nitric Oxide - metabolism | Galactosamine - toxicity | Inflammation - physiopathology | Index Medicus | OXIDATION | APOPTOSIS | ANTIOXIDANTS | CHOLESTEROL | NITRIC OXIDE | ALBUMINS | RATS | TRIGLYCERIDES | DEATH | TOXICITY | ALKALINE PHOSPHATASE | 60 APPLIED LIFE SCIENCES | LACTATE DEHYDROGENASE | NECROSIS | HEME | MESSENGER-RNA | ALANINES | GLUTATHIONE | INFLAMMATION | GENES | LIVER | LIVER CELLS | QUININE
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