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British Journal of Pharmacology, ISSN 0007-1188, 07/2018, Volume 175, Issue 14, p. 2911
Experimental Approach Based on our data, we conclude that galantamine is not a positive allosteric modulator of [alpha]7 or [alpha]4[beta]2 receptors, which... 
Evaluation | Galanthamine | Alzheimer's disease
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2015, Volume 11, Issue 7, pp. P840 - P840
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2015, Volume 11, Issue 7, pp. P747 - P748
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 2009, Volume 131, Issue 44, pp. 16045 - 16047
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2014, Volume 10, Issue 4, pp. P449 - P450
Journal Article
Tetrahedron, ISSN 0040-4020, 08/2017, Volume 73, Issue 32, pp. 4719 - 4722
A rapid synthesis of Guillou's Galanthamine intermediate was achieved starting from commercially available 6-bromoguaiacol. The improved synthetic route... 
Intermediate | Cyclization | Galanthamine | 6-Bromoguaiacol | Suzuki reaction | REAGENT | DRUG | (-)-GALANTHAMINE | CHEMISTRY, ORGANIC | COUPLING REACTIONS | AMARYLLIDACEAE | (+/-)-GALANTHAMINE | ALKALOIDS | Substitution reactions
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2013, Volume 9, Issue 4, pp. P659 - P660
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 06/2018, Volume 59, Issue 23, pp. 2293 - 2295
An unprecedented 7-membered ring cyclization of an enamide to a phenol through hypervalent iodine phenolic oxidation was discovered. In the process a molecule... 
Enamide | Phenolic oxidation | Hypervalent iodine | Galanthamine | 7-Membered ring cyclization | (-)-GALANTHAMINE | CHEMISTRY, ORGANIC | (+)-GALANTHAMINE | ALKALOIDS | Oxidation-reduction reaction | Synthesis | Organic compounds | Chemical Sciences
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 12/2016, Volume 2016, Issue 35, pp. 5862 - 5867
Narwedine, an immediate precursor to the therapeutically valuable alkaloid (–)‐galanthamine, has been synthesised by engaging an iodinated isovanillin... 
Heck reaction | Alkaloids | Synthesis design | Amination | Mitsunobu reaction | (-)-GALANTHAMINE | FORMAL SYNTHESIS | CHEMISTRY, ORGANIC | (-)-LYCORAMINE | CYCLOADDITION | BIOSYNTHESIS | AMARYLLIDACEAE | (+)-GALANTHAMINE | (+/-)-GALANTHAMINE | (-)-MORPHINE | ASYMMETRIC TOTAL-SYNTHESIS | Substitution reactions
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2012, Volume 8, Issue 4, pp. P586 - P586
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2012, Volume 8, Issue 4, pp. P190 - P191
Journal Article
Computers and Chemical Engineering, ISSN 0098-1354, 07/2019, Volume 126, p. 231
In this paper, a 10th order nonlinear pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate the impact of Alzheimer's disease (AD)... 
Drugs | Choline | Models | Acetylcholine | Galanthamine | Alzheimer's disease
Journal Article
Organic Letters, ISSN 1523-7060, 08/2016, Volume 18, Issue 15, pp. 3798 - 3801
The racemic form of the title natural product 1 has been synthesized by engaging, as a key step, the iodoarenetethered cyclohexene 22 in an intramolecular Heck... 
GALANTHAMINE | (-)-GALANTHAMINE | ENANTIOSELECTIVE SYNTHESIS | BARK | NEUROTROPHIC ACTIVITY | CHEMISTRY, ORGANIC | DUNNIANUM | LIGNANS | (-)-MORPHINE | NEOLIGNANS
Journal Article
Clinical Therapeutics, ISSN 0149-2918, 08/2015, Volume 37, Issue 8, p. e31
  [...]here we aimed to verify the potential antidiabetic effect and to unveil the possible mechanisms of galantamine, a clinically approved... 
Galanthamine | Insulin | Diabetes | Lipids | Rodents
Journal Article
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2014, Volume 10, Issue 4, pp. P467 - P468
Journal Article
Synlett, ISSN 0936-5214, 02/2013, Volume 24, Issue 3, pp. 379 - 382
Abstract Asymmetric total synthesis of (–)-galanthamine was accomplished starting from an epoxide. Intramolecular Heck reaction of a conjugated diene system... 
letter | Heck reaction | (-)-galanthamine | epoxides | total synthesis | metathesis | EFFICIENT TOTAL-SYNTHESIS | ALZHEIMER DRUG (-)-GALANTHAMINE | ENANTIOSELECTIVE SYNTHESIS | OLEFIN METATHESIS REACTIONS | CHEMISTRY, ORGANIC | ALLYLIC OXIDATION | CHOLINESTERASE-INHIBITORS | TERT-BUTYL HYDROPEROXIDE | GALANTHAMINE RING-SYSTEM | MITSUNOBU REACTION | SELENIUM DIOXIDE
Journal Article
Organic Letters, ISSN 1523-7060, 08/2015, Volume 17, Issue 17, pp. 4356 - 4359
A distinct strategy via unprecedented semipinacol rearrangements for the synthesis of functionalized hydrodibenzofurans is reported. The versatile reactivity... 
GALANTHAMINE | (-)-GALANTHAMINE | FORMAL SYNTHESIS | MORPHINE | PRODUCT | DRUG DISCOVERY | CHEMISTRY, ORGANIC | (-)-LYCORAMINE | QUATERNARY CARBON STEREOCENTERS | ASYMMETRIC TOTAL-SYNTHESIS | ALKALOIDS
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 2007, Volume 48, Issue 36, pp. 6267 - 6270
The stereoselective total synthesis of (+)-galanthamine starting from -glucose is described. The quaternary carbon in was stereoselectively generated via... 
Galanthamine | Chiral synthesis | Claisen rearrangement | galanthamine | AMARYLLIDACEAE ALKALOIDS | ORGANIC-SYNTHESIS | (-)-GALANTHAMINE | ALZHEIMERS-DISEASE | chiral synthesis | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | (+/-)-GALANTHAMINE | REMOTE ASYMMETRIC INDUCTION | L-TYROSINE
Journal Article
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