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Blood, ISSN 0006-4971, 05/2017, Volume 129, Issue 19, pp. 2624 - 2635
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2009, Volume 119, Issue 4, pp. 964 - 975
Journal Article
Cell Reports, ISSN 2211-1247, 10/2017, Volume 21, Issue 1, pp. 17 - 26
Antigen-independent tonic signaling by chimeric antigen receptors (CARs) can increase differentiation and exhaustion of T cells, limiting their potency.... 
adoptive T cell therapy | 4-1BB | chimeric antigen receptor | costimulation | T cells | adoptive T cell therapy | ACTIVATION | LIGAND EXPRESSION | CAR | EFFECTOR FUNCTION | GENE-EXPRESSION | FAS | DEATH | ANTITUMOR-ACTIVITY | NF-KAPPA-B | SIGNALING COMPLEX | CELL BIOLOGY | Neoplasm Transplantation | Humans | Mutant Chimeric Proteins - genetics | NF-kappa B - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 9 - genetics | T-Lymphocytes - transplantation | Leukemia-Lymphoma, Adult T-Cell - immunology | Lentivirus - metabolism | fas Receptor - immunology | Cell Death | fas Receptor - genetics | Lentivirus - genetics | Receptors, Antigen, T-Cell - immunology | 4-1BB Ligand - immunology | T-Lymphocytes - pathology | 4-1BB Ligand - genetics | Antigens, Neoplasm - genetics | Genetic Vectors - chemistry | Signal Transduction | Antigens, Neoplasm - immunology | Cell Survival | Leukemia-Lymphoma, Adult T-Cell - genetics | Tumor Necrosis Factor Receptor Superfamily, Member 9 - immunology | Genetic Vectors - metabolism | Gene Expression Regulation, Leukemic | Leukemia-Lymphoma, Adult T-Cell - pathology | Gammaretrovirus - metabolism | Animals | Gammaretrovirus - genetics | NF-kappa B - genetics | Mice, Inbred NOD | Mutant Chimeric Proteins - immunology | T-Lymphocytes - immunology | Mice | Receptors, Antigen, T-Cell - genetics | Index Medicus | Chimeric antigen receptor
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2008, Volume 118, Issue 9, pp. 3132 - 3142
Journal Article
BMC Cancer, ISSN 1471-2407, 06/2010, Volume 10, Issue 1, pp. 326 - 326
Journal Article
The Lancet, ISSN 0140-6736, 12/2004, Volume 364, Issue 9452, pp. 2181 - 2187
X-linked severe combined immunodeficiency (SCID-X1) is caused by mutations in the common cytokine-receptor γchain(γc), resulting in disruption of development... 
LONG-TERM | MEDICINE, GENERAL & INTERNAL | VIVO | BONE-MARROW | STEM-CELL TRANSPLANTATION | VERSUS-HOST-DISEASE | GAMMA-CHAIN | Antigens, CD34 - analysis | Humans | Child, Preschool | Infant | Immunity | Lymphocyte Culture Test, Mixed | Receptors, Interleukin-7 - genetics | Bone Marrow Cells - immunology | Bone Marrow Transplantation | Immunoglobulins - blood | Genetic Diseases, X-Linked - genetics | Gene Transfer Techniques | Transduction, Genetic | Lymphocyte Activation | Severe Combined Immunodeficiency - therapy | Severe Combined Immunodeficiency - immunology | Severe Combined Immunodeficiency - genetics | Gammaretrovirus | T-Lymphocytes - immunology | Interleukin Receptor Common gamma Subunit | Mutation | Genetic Vectors | Genetic Diseases, X-Linked - therapy | Genetic Therapy - adverse effects | Genetic Therapy - methods | Gene therapy | Research | Bone marrow | Clinical trials | Transplants & implants | Autoimmune diseases | Severe combined immunodeficiency | Leukemia | Bone marrow transplantation | Recovery of function | Viruses | Transplantation | Lymphocytes T | T-cell receptor | Killer cells | Immunology | Restoration | Lymphocytes | Immunity (humoral) | Children | CD34 antigen | Antigens | Autografts | Immunoglobulins | Cytokines | Patients | Morbidity | Chemotherapy | Lymphocytes B | Stem cells | Histocompatibility antigen HLA | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Current Gene Therapy, ISSN 1566-5232, 07/2015, Volume 15, Issue 4, pp. 416 - 427
Journal Article
Science, ISSN 0036-8075, 7/2011, Volume 333, Issue 6038, pp. 97 - 101
Journal Article