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The lancet oncology, ISSN 1470-2045, 2014, Volume 15, Issue 12, pp. 1389 - 1396
Journal Article
Diabetes, Obesity and Metabolism, ISSN 1462-8902, 12/2017, Volume 19, Issue 12, pp. 1751 - 1761
Aims There are no treatments for the extreme hyperphagia and obesity in Prader–Willi syndrome (PWS). The bestPWS clinical trial assessed the efficacy, safety... 
clinical trial | antiobesity drug | appetite control | randomized trial | phase III study | MANAGEMENT | ADULTS | ADIPONECTIN LEVELS | OBESE WOMEN | CHILDREN | PROTEIN-LEVELS | LAPAROSCOPIC SLEEVE GASTRECTOMY | TNP-470 | ADOLESCENTS | ENDOCRINOLOGY & METABOLISM | MATCHED-CONTROL | Appetite Depressants - adverse effects | Venous Thrombosis - chemically induced | Cinnamates - administration & dosage | Humans | Glycoproteins - metabolism | Male | Cyclohexanes - administration & dosage | Sesquiterpenes - administration & dosage | Weight Loss - drug effects | Appetite Depressants - therapeutic use | Sesquiterpenes - adverse effects | Sesquiterpenes - therapeutic use | Dose-Response Relationship, Drug | Young Adult | Cyclohexanes - therapeutic use | Early Termination of Clinical Trials | Epoxy Compounds - administration & dosage | Prader-Willi Syndrome - physiopathology | Protease Inhibitors - administration & dosage | Protease Inhibitors - adverse effects | Adult | Appetite Depressants - administration & dosage | Female | Obesity - etiology | Cyclohexanes - adverse effects | Protease Inhibitors - therapeutic use | Aminopeptidases - metabolism | Prader-Willi Syndrome - drug therapy | Body Mass Index | Severity of Illness Index | Epoxy Compounds - therapeutic use | Hyperphagia - etiology | Double-Blind Method | Glycoproteins - antagonists & inhibitors | Venous Thrombosis - physiopathology | Aminopeptidases - antagonists & inhibitors | Hyperphagia - prevention & control | Hyperphagia - physiopathology | Obesity - prevention & control | Adolescent | Intention to Treat Analysis | Cinnamates - adverse effects | Cinnamates - therapeutic use | Epoxy Compounds - adverse effects | Pulmonary embolism | Medical research | Prader-Willi syndrome | Analysis | Body weight | Clinical trials | Medicine, Experimental | Hyperphagia | Obesity | Statistical analysis | Methionine | Body weight loss | Injection | Thrombosis | Evidence-based medicine | Embolism | Weight control | Motivation | Aminopeptidase
Journal Article
The lancet oncology, ISSN 1470-2045, 2017, Volume 18, Issue 5, pp. 640 - 653
Summary Background Although trastuzumab plus chemotherapy is the standard of care for first-line treatment of HER2-positive advanced gastric cancer, there is... 
Hematology, Oncology and Palliative Medicine | SURVIVAL | SUPPORTIVE CARE | WEEKLY PACLITAXEL | ONCOLOGY | 2ND-LINE CHEMOTHERAPY | IRINOTECAN | LEVEL | PLUS PACLITAXEL | HER2 | CANCER | DOCETAXEL | Follow-Up Studies | Febrile Neutropenia - chemically induced | Humans | Middle Aged | Male | Stomach Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Taxoids - therapeutic use | Antineoplastic Agents - adverse effects | Pneumonia - chemically induced | Aged, 80 and over | Adult | Female | Stomach Neoplasms - chemistry | Adenocarcinoma - chemistry | Taxoids - adverse effects | Antibodies, Monoclonal, Humanized - adverse effects | Maytansine - adverse effects | Bridged-Ring Compounds - therapeutic use | Antibodies, Monoclonal, Humanized - therapeutic use | Maytansine - analogs & derivatives | Anemia - chemically induced | Survival Rate | Thrombocytopenia - chemically induced | Stomach Neoplasms - drug therapy | Maytansine - therapeutic use | Adenocarcinoma - drug therapy | Adenocarcinoma - secondary | Esophagogastric Junction | Gastrointestinal Hemorrhage - chemically induced | Retreatment | Intention to Treat Analysis | Bridged-Ring Compounds - adverse effects | Aged | Receptor, ErbB-2 - analysis | Trastuzumab | Adenocarcinoma | Medical research | Chemotherapy | Clinical trials | Medicine, Experimental | Metastasis | Esophageal cancer | Cancer | Analysis
Journal Article
Journal of clinical oncology, ISSN 1527-7755, 2014, Volume 32, Issue 5, pp. 385 - 391
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2012, Volume 379, Issue 9813, pp. 315 - 321
Journal Article
Journal Article
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 01/2018, Volume 319, Issue 3, pp. 255 - 265
Journal Article
Journal Article
Journal Article
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 01/2018, Volume 319, Issue 3, pp. 241 - 254
IMPORTANCE: Laparoscopic sleeve gastrectomy for treatment of morbid obesity has increased substantially despite the lack of long-term results compared with... 
MEDICINE, GENERAL & INTERNAL | MULTICENTER | METAANALYSIS | LIFE-STYLE | GASTROESOPHAGEAL-REFLUX DISEASE | INTENSIVE MEDICAL-MANAGEMENT | TERM-FOLLOW-UP | BARIATRIC SURGERY | COMPLICATIONS | OUTCOMES | TYPE-2 DIABETES-MELLITUS | Follow-Up Studies | Obesity, Morbid - surgery | Humans | Middle Aged | Gastric Bypass - adverse effects | Male | Treatment Outcome | Laparoscopy | Obesity, Morbid - complications | Young Adult | Gastrectomy - methods | Obesity, Morbid - physiopathology | Weight Loss | Adolescent | Gastrectomy - adverse effects | Hypertension - complications | Quality of Life | Adult | Female | Gastric Bypass - methods | Postoperative Complications | Diabetes Mellitus, Type 2 - complications | Hyperlipidemias - complications | Obesity | Usage | Care and treatment | Analysis | Gastric bypass | Weight loss | Clinical trials | Laparoscopic surgery | Comparative analysis | Health aspects | Drugs | Dyslipidemia | Body weight loss | Criteria | Weight loss measurement | Body mass index | Randomization | Remission | Diabetes mellitus (non-insulin dependent) | Significance | Hypertension | Statistical analysis | Mortality | Diabetes mellitus | Gastrectomy | Patients | Morbidity | Quality of life | Weight control | Equivalence | Body mass | Body size | Gastrointestinal surgery | Bypasses | Original Investigation | Research
Journal Article
Journal Article
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 05/2017, Volume 317, Issue 20, pp. 2097 - 2104
Journal Article