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Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 08/2015, Volume 96, Issue 3, pp. 237 - 246
Journal Article
Journal Article
Journal Article
Peptides, ISSN 0196-9781, 02/2018, Volume 100, pp. 202 - 211
Combined modulation of peptide hormone receptors including, glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP) and xenin, have... 
Hybrid | Xenin | Glucagon-like-peptide-1 (GLP-1) | Glucose-dependent insulinotropic polypeptide (GIP) | Glucose homeostasis | Insulin secretion | OBESE-DIABETIC OB/OB | GLP-1 RECEPTOR AGONISTS | DB/DB MICE | BIOCHEMISTRY & MOLECULAR BIOLOGY | POSTPRANDIAL GLUCOSE | IV-RESISTANT | BETA-CELL FUNCTION | GLUCAGON-LIKE PEPTIDE-1 | ENDOCRINOLOGY & METABOLISM | PHARMACOLOGY & PHARMACY | GASTROINTESTINAL HORMONES | DEPENDENT INSULINOTROPIC POLYPEPTIDE | GASTRIC-INHIBITORY POLYPEPTIDE | Glucagon-Like Peptide 1 - administration & dosage | Humans | Diet, High-Fat - adverse effects | Diabetes Mellitus, Type 2 - metabolism | Exenatide - chemistry | Neurotensin - chemistry | Hypoglycemic Agents - administration & dosage | Glucagon - chemistry | Neurotensin - administration & dosage | Disease Models, Animal | Glucagon-Like Peptide 1 - chemistry | Hypoglycemic Agents - chemistry | Gastric Inhibitory Polypeptide - administration & dosage | Blood Glucose - drug effects | Insulin - metabolism | Animals | Gastric Inhibitory Polypeptide - chemistry | Insulin-Secreting Cells - drug effects | Glucose - metabolism | Exenatide - administration & dosage | Glucagon - metabolism | Mice | Diabetes Mellitus, Type 2 - pathology | Diabetes Mellitus, Type 2 - drug therapy | Drug Combinations | Type 2 diabetes | Blood cholesterol | Low density lipoproteins | Body weight | Homeostasis | Glucose | Cholecystokinin | Insulin | Dextrose | Glutamine | Index Medicus
Journal Article
Diabetologia, ISSN 0012-186X, 3/2016, Volume 59, Issue 3, pp. 533 - 541
Glucose-dependent insulinotropic polypeptide (GIP) is a peptide hormone released from gut K cells. While the predominant form is GIP(1–42), a shorter form,... 
Alpha cell | Medicine & Public Health | Human Physiology | Glucagon | Polyethylene glycol | Metabolic Diseases | Beta cell | Glucose-dependent insulinotropic polypeptide(1–30) | Internal Medicine | Insulin | Streptozotocin | Glucose-dependent insulinotropic polypeptide(1-30) | DOWN-REGULATION | RECEPTOR | BETA-CELL FUNCTION | IN-VITRO | OBESITY | ENDOCRINOLOGY & METABOLISM | DEGRADATION | FAT-FED MICE | GASTRIC-INHIBITORY POLYPEPTIDE | DIPEPTIDYL PEPTIDASE-IV | Hypoglycemic Agents - therapeutic use | Immunohistochemistry | Diabetes Mellitus, Experimental - drug therapy | Peptide Fragments - metabolism | Gastric Inhibitory Polypeptide - metabolism | Hypoglycemic Agents - metabolism | Dipeptidyl-Peptidase IV Inhibitors - therapeutic use | Gastric Inhibitory Polypeptide - therapeutic use | Mice, Inbred C57BL | Body Weight - drug effects | Male | Hypoglycemic Agents - chemistry | Hyperglycemia - drug therapy | Streptozocin - pharmacology | Peptide Fragments - chemistry | Animals | Hyperglycemia - chemically induced | Gastric Inhibitory Polypeptide - chemistry | Glucagon - metabolism | Cell Proliferation - drug effects | Mice | Peptide Fragments - therapeutic use | Diabetes Mellitus, Experimental - metabolism | Hyperglycemia | Chorionic gonadotropin | Analysis | Dosage and administration | Cholecystokinin | Diabetes | Glucose | Polyols | Dextrose | Index Medicus
Journal Article
Bone, ISSN 8756-3282, 2016, Volume 91, pp. 102 - 112
Abstract A role for glucose-dependent insulinotropic polypeptide (GIP) in controlling bone resorption has been suspected. However uncertainty remains to... 
Orthopedics | Bone resorption | Osteoclastogenesis | [d-Ala2]-GIP | Osteoclast | N-AcGIP | D-Ala | GIP | ACTIVATION | RECEPTOR | INCRETINS | STRENGTH | [D-Ala]-GIP | PHOSPHATE | REDUCTION | COLOCALIZATION | ENDOCRINOLOGY & METABOLISM | MICE | INHIBITS BONE-RESORPTION | EXPRESSION | Leukocytes, Mononuclear - metabolism | Calcium - metabolism | Gastric Inhibitory Polypeptide - therapeutic use | Humans | Male | Cancellous Bone - drug effects | Cortical Bone - pathology | Protein Transport - drug effects | X-Ray Microtomography | Cancellous Bone - diagnostic imaging | Cell Nucleus - metabolism | Cancellous Bone - pathology | Gastric Inhibitory Polypeptide - pharmacology | Cyclic AMP - metabolism | Peptide Hydrolases - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Amino Acid Sequence | Osteoclasts - pathology | Leukocytes, Mononuclear - drug effects | Bone Resorption - drug therapy | Adenylyl Cyclases - metabolism | Leukocytes, Mononuclear - pathology | Animals | Gastric Inhibitory Polypeptide - chemistry | Signal Transduction - drug effects | Cell Differentiation - drug effects | Bone Resorption - pathology | Cortical Bone - drug effects | RAW 264.7 Cells | Mice | Mice, Inbred BALB C | Cell Nucleus - drug effects | Cortical Bone - diagnostic imaging | Osteoclasts - drug effects | Analysis | Dextrose | Glucose | Collagen | Index Medicus | Life Sciences
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2005, Volume 280, Issue 23, pp. 22297 - 22307
Journal Article
Diabetologia, ISSN 0012-186X, 8/2007, Volume 50, Issue 8, pp. 1752 - 1762
Gastric inhibitory polypeptide (GIP) receptor antagonism with (Pro3)GIP improves glucose tolerance and ameliorates insulin resistance and abnormalities of... 
Obesity-related diabetes | Gastric inhibitory polypeptide antagonist | Gastric inhibitory polypeptide | Diet-induced obesity | Medicine & Public Health | Human Physiology | Metabolic Diseases | Internal Medicine | Insulin resistance | (Pro 3 )GIP | Pro | GIP | obesity-related diabetes | polypeptide | ADIPOCYTES | LIPOPROTEIN-LIPASE ACTIVITY | HYPERGLYCEMIC OB/OB MICE | gastric inhibitory | diet-induced obesity | DIABETES-MELLITUS | BODY-WEIGHT | (Pro)GIP | gastric inhibitory polypeptide antagonist | ENDOCRINOLOGY & METABOLISM | PLASMA-GLUCOSE | INCRETIN RECEPTORS | insulin resistance | RAT ADIPOSE-TISSUE | HORMONES | Glycated Hemoglobin A - metabolism | Body Weight - drug effects | Male | Insulin - blood | Glucagon - blood | Obesity - blood | Glucose Intolerance - prevention & control | Dietary Fats - pharmacology | Lipids - blood | Dietary Fats - administration & dosage | Corticosterone - blood | Gastric Inhibitory Polypeptide - pharmacology | Locomotion - drug effects | Insulin Resistance | Obesity - physiopathology | Gastric Inhibitory Polypeptide - administration & dosage | Receptors, Gastrointestinal Hormone - antagonists & inhibitors | Adiponectin - blood | Eating - drug effects | Animals | Gastric Inhibitory Polypeptide - chemistry | Obesity - prevention & control | Mice, Obese | Mice | Blood Glucose - metabolism | Obesity | Pancreatic beta cells | Glucose intolerance | Diet | Food services | Blood lipids | Glucagon | Corticosterone | Body weight | Triglycerides | Glucose | Dextrose | Index Medicus
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 11/2016, Volume 120, pp. 33 - 45
Until very recently, G-protein dependent signal of GPCRs was thought to originate exclusively from the plasma membrane and internalized GPCRs were considered... 
BRET | FRET | cAMP | Glucose-dependent-insulinotropic receptor | Internalization | Early endosomes | LOCALIZATION | TSH RECEPTORS | COMPLEX | ARRESTIN | DESENSITIZATION | ENDOCYTOSIS | Glucose-dependent-Insulinotropic receptor | BIOLOGY | PHARMACOLOGY & PHARMACY | GENERATION | BINDING | GTP-Binding Protein alpha Subunits, Gs - metabolism | Receptors, Gastrointestinal Hormone - chemistry | GTP-Binding Protein alpha Subunits, Gs - chemistry | Gastric Inhibitory Polypeptide - metabolism | Single-Domain Antibodies - metabolism | Humans | Cyclic AMP-Dependent Protein Kinases - chemistry | rab GTP-Binding Proteins - genetics | Green Fluorescent Proteins - genetics | Receptors, Gastrointestinal Hormone - metabolism | Receptors, Gastrointestinal Hormone - agonists | Recombinant Fusion Proteins - metabolism | Endosomes - metabolism | GTP-Binding Protein alpha Subunits, Gs - genetics | Chromogranins - metabolism | Endocytosis | Cyclic AMP-Dependent Protein Kinases - genetics | HEK293 Cells | Fluorescence Resonance Energy Transfer | Chromogranins - genetics | Cyclic AMP - metabolism | Peptide Fragments - genetics | Second Messenger Systems | Cyclic AMP-Dependent Protein Kinases - metabolism | Recombinant Proteins - metabolism | rab GTP-Binding Proteins - metabolism | Fluorescent Dyes - chemistry | Green Fluorescent Proteins - metabolism | Peptide Fragments - metabolism | Recombinant Proteins - chemistry | Adenylyl Cyclases - metabolism | Recombinant Fusion Proteins - chemistry | Bioluminescence Resonance Energy Transfer Techniques | Gastric Inhibitory Polypeptide - genetics | Protein Transport | Peptide Fragments - chemistry | Gastric Inhibitory Polypeptide - chemistry | Chromogranins - chemistry | Receptors, Gastrointestinal Hormone - genetics | Adenylyl Cyclases - chemistry | Luminescent Proteins - genetics | Endosomes - enzymology | Cyclic AMP - agonists | Adenylyl Cyclases - genetics | Single-Domain Antibodies - genetics | Luminescent Proteins - metabolism | Peptides | Dextrose | Glucose | Index Medicus
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 2009, Volume 78, Issue 8, pp. 1008 - 1016
C-terminal acylation of Lys with myristic (MYR; tetradecanoic acid), palmitic (PAL; hexadecanoic acid) and stearic (octadecanoic acid) fatty acids with or... 
Dipeptidylpeptidase-IV (DPP-IV) |