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1. Full Text Cancer Cachexia in the Age of Obesity: Skeletal Muscle Depletion Is a Powerful Prognostic Factor, Independent of Body Mass Index
by Lisa Martin and Laura Birdsell and Neil MacDonald and Tony Reiman and M. Thomas Clandinin and Linda J. McCargar and Rachel Murphy and Sunita Ghosh and Michael B. Sawyer and Vickie E. Baracos
Journal of Clinical Oncology, ISSN 0732-183X, 04/2013, Volume 31, Issue 12, pp. 1539 - 1547
Purpose Emerging evidence suggests muscle depletion predicts survival of patients with cancer. Patients and Methods At a cancer center in Alberta, Canada,... 
SURVIVAL | TOMOGRAPHY | ONCOLOGY | NUTRITIONAL-STATUS | TISSUE | DETERMINANT | US ADULTS | SARCOPENIA | PREVALENCE | CHEMOTHERAPY TOXICITY | CARE | Body Composition | Prognosis | Age Factors | Follow-Up Studies | Cachexia - diagnosis | Gastrointestinal Neoplasms - mortality | Lung Neoplasms - mortality | Humans | Middle Aged | Gastrointestinal Neoplasms - complications | Male | Canada - epidemiology | Cachexia - etiology | Adult | Female | Body Mass Index | Cachexia - mortality | Risk Factors | Survival Rate | Lung Neoplasms - therapy | Gastrointestinal Neoplasms - therapy | Cancer Care Facilities | Lung Neoplasms - complications | Obesity - epidemiology | Aged | Muscle, Skeletal - pathology | Neoplasm Staging | Index Medicus
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2. Full Text Phase II pilot study of vemurafenib in patients with metastatic BRAF-mutated colorectal cancer
by Kopetz, Scott and Desai, Jayesh and Chan, Emily and Hecht, Joel Randolph and O'Dwyer, Peter J and Maru, Dipen and Morris, Van and Janku, Filip and Dasari, Arvind and Chung, Woonbook and Issa, Jean-Pierre J and Gibbs, Peter and James, Brian and Powis, Garth and Nolop, Keith B and Bhattacharya, Suman and Saltz, Leonard
Journal of Clinical Oncology, ISSN 0732-183X, 12/2015, Volume 33, Issue 34, pp. 4032 - 4038
Purpose BRAF V600E mutation is seen in 5% to 8% of patients with metastatic colorectal cancer (CRC) and is associated with poor prognosis. Vemurafenib, an oral... 
COLON-CANCER | SURVIVAL | INHIBITION | MELANOMA | ONCOLOGY | PROGNOSIS | MICROSATELLITE INSTABILITY | RESISTANCE | MUTATIONS | PROGRESSION | Prognosis | Skin Neoplasms - drug therapy | Follow-Up Studies | Carcinoma, Squamous Cell - genetics | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Tissue Distribution | Carcinoma, Squamous Cell - mortality | Skin Neoplasms - mortality | Colorectal Neoplasms - drug therapy | Aged, 80 and over | Adult | Female | Colorectal Neoplasms - mortality | Survival Rate | Mutation - genetics | Sulfonamides - pharmacokinetics | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Pilot Projects | Carcinoma, Squamous Cell - drug therapy | Sulfonamides - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Skin Neoplasms - genetics | Skin Neoplasms - secondary | Carcinoma, Squamous Cell - secondary | Indoles - pharmacokinetics | Indoles - therapeutic use | Aged | Colorectal Neoplasms - pathology | Neoplasm Staging | Cohort Studies | Index Medicus | Gic5 | ORIGINAL REPORTS | Gic7
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3. Full Text Intraperitoneal Chemotherapy of Peritoneal Carcinomatosis Using Pressurized Aerosol as an Alternative to Liquid Solution: First Evidence for Efficacy
by Solass, Wiebke and Kerb, Reinhold and Mürdter, Thomas and Giger-Pabst, Urs and Strumberg, Dirk and Tempfer, Clemens and Zieren, Jürgen and Schwab, Matthias and Reymond, Marc André
Annals of Surgical Oncology, ISSN 1068-9265, 2/2014, Volume 21, Issue 2, pp. 553 - 559
Peritoneal carcinomatosis (PC) is an unmet medical need. Despite recent improvements, systemic chemotherapy has limited efficacy. We report the first... 
Oncology | Medicine & Public Health | Surgical Oncology | Surgery | SURGERY | CYTOREDUCTIVE SURGERY | ONCOLOGY | DOXORUBICIN | INTRAABDOMINAL PRESSURE | PENETRATION | CANCER | Humans | Middle Aged | Ovarian Neoplasms - pathology | Male | Stomach Neoplasms - pathology | Ovarian Neoplasms - mortality | Peritoneal Neoplasms - drug therapy | Adult | Appendiceal Neoplasms - drug therapy | Female | Ovarian Neoplasms - drug therapy | Peritoneal Neoplasms - secondary | Injections, Intraperitoneal | Survival Rate | Treatment Outcome | Stomach Neoplasms - drug therapy | Appendiceal Neoplasms - mortality | Peritoneal Neoplasms - mortality | Pressure | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aerosols | Aged | Appendiceal Neoplasms - pathology | Neoplasm Staging | Stomach Neoplasms - mortality | Chemotherapy | Anthracyclines | Cancer | Index Medicus | Gastrointestinal Oncology
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4. Full Text Gastrointestinal Bleeding Due to Gastrointestinal Tract Malignancy: Natural History, Management, and Outcomes
by Schatz, Richard A and Rockey, Don C
Digestive Diseases and Sciences, ISSN 0163-2116, 2/2017, Volume 62, Issue 2, pp. 491 - 501
Gastrointestinal (GI) tumor bleeding can vary from occult bleeding to massive hemorrhage and can be the presenting sign of malignancy.Our primary aims were to:... 
Biochemistry, general | Neoplasm | Mass | Melena | Medicine & Public Health | Hepatology | Gastroenterology | Oncology | Ulcer | Hemorrhage | Hematemesis | Transplant Surgery | MORTALITY | GASTROENTEROLOGY & HEPATOLOGY | CANCER | Adenocarcinoma - pathology | Gastrointestinal Neoplasms - mortality | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | Jejunal Neoplasms - mortality | Lymphoma - mortality | Duodenal Neoplasms - complications | Esophageal Neoplasms - pathology | Neoplasm Metastasis | Gastrointestinal Stromal Tumors - mortality | Duodenal Neoplasms - pathology | Ileal Neoplasms - pathology | Stomach Neoplasms - complications | Endoscopy, Gastrointestinal | Hematemesis - etiology | Adenocarcinoma - secondary | Disease Progression | Ileal Neoplasms - complications | Carcinoma, Squamous Cell - complications | Stomach Neoplasms - mortality | Gastrointestinal Neoplasms - secondary | Prognosis | Duodenal Neoplasms - mortality | Gastrointestinal Neoplasms - complications | Stomach Neoplasms - pathology | Gastrointestinal Neoplasms - pathology | Esophageal Neoplasms - complications | Carcinoma, Squamous Cell - mortality | Gastrointestinal Stromal Tumors - pathology | Jejunal Neoplasms - complications | Esophageal Neoplasms - mortality | Female | Lymphoma - pathology | Retrospective Studies | Melena - etiology | Colonic Neoplasms - mortality | Ileal Neoplasms - mortality | Cross-Sectional Studies | Adenocarcinoma - complications | Colonic Neoplasms - complications | Gastrointestinal Hemorrhage - etiology | Colonic Neoplasms - pathology | Lymphoma - complications | Carcinoma, Squamous Cell - secondary | Gastrointestinal Stromal Tumors - complications | Aged | Adenocarcinoma - mortality | Jejunal Neoplasms - pathology | Medical colleges | Colon cancer | Gastrointestinal bleeding | Gastrointestinal diseases | Mortality | Gastrointestinal system | Metastasis | Cancer | Index Medicus | Abridged Index Medicus
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5. Full Text Hospital volume and late survival after cancer surgery
by Birkmeyer, John D and Sun, Yating and Wong, Sandra L and Stukel, Therese A
Annals of Surgery, ISSN 0003-4932, 05/2007, Volume 245, Issue 5, pp. 777 - 783
Context: Although hospital procedure volume is clearly related to operative mortality with many cancer procedures, its effect on late survival is not well... 
UNITED-STATES | BREAST-CANCER | MORTALITY | SURGERY | POPULATION | DISPARITIES | SEER-MEDICARE DATA | RESECTION | LONG-TERM SURVIVAL | HEALTH-CARE | COMORBIDITY | United States - epidemiology | SEER Program | Urinary Bladder Neoplasms - mortality | Gastrointestinal Neoplasms - mortality | Lung Neoplasms - mortality | Humans | Pancreatic Neoplasms - surgery | Gastrointestinal Neoplasms - surgery | Male | Surgical Procedures, Operative - statistics & numerical data | Survival Rate | Urinary Bladder Neoplasms - surgery | Aged, 80 and over | Female | Lung Neoplasms - surgery | Aged | Pancreatic Neoplasms - mortality | Retrospective Studies | Health Facility Size | Index Medicus | Abridged Index Medicus | Original
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6. Full Text Microparticle‐associated tissue factor activity, venous thromboembolism and mortality in pancreatic, gastric, colorectal and brain cancer patients
by THALER, J and AY, C and MACKMAN, N and BERTINA, R. M and KAIDER, A and MAROSI, C and KEY, N. S and BARCEL, D. A and SCHEITHAUER, W and KORNEK, G and ZIELINSKI, C and PABINGER, I
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 07/2012, Volume 10, Issue 7, pp. 1363 - 1370
Background:  Tissue factor (TF) expression by tumors contributes to tumor growth. Release of TF‐positive microparticles (MPs) may contribute to venous... 
mortality | microparticles | cancer | tissue factor | prospective study | venous thromboembolism | Prospective study | Mortality | Microparticles | Venous thromboembolism | Tissue factor | Cancer | CELLS | THROMBOSIS | FACTOR EXPRESSION | FACTOR-BEARING MICROPARTICLES | PERIPHERAL VASCULAR DISEASE | VIENNA CANCER | HEMATOLOGY | Venous Thromboembolism - mortality | Prospective Studies | Fibrin Fibrinogen Degradation Products - metabolism | Gastrointestinal Neoplasms - mortality | Humans | Middle Aged | Probability | Gastrointestinal Neoplasms - complications | Male | Survival Rate | Brain Neoplasms - complications | Venous Thromboembolism - blood | Gastrointestinal Neoplasms - blood | Venous Thromboembolism - complications | Brain Neoplasms - blood | Female | Aged | Brain Neoplasms - mortality | Thromboplastin - metabolism | Brain | pancreatic cancer | thromboembolism | Kinetics | Tissues | Tumors | Index Medicus
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7. Full Text Everolimus for the treatment of advanced, non-functional neuroendocrine tumours of the lung or gastrointestinal tract (RADIANT-4): a randomised, placebo-controlled, phase 3 study
by Yao, James C, Dr and Fazio, Nicola, MD and Singh, Simron, MD and Buzzoni, Roberto, MD and Carnaghi, Carlo, MD and Wolin, Edward, MD and Tomasek, Jiri, MD and Raderer, Markus, MD and Lahner, Harald, MD and Voi, Maurizio, MD and Pacaud, Lida Bubuteishvili, MD and Rouyrre, Nicolas, MSc and Sachs, Carolin, RN and Valle, Juan W, MD and Fave, Gianfranco Delle, MD and Van Cutsem, Eric, MD and Tesselaar, Margot, MD and Shimada, Yasuhiro, MD and Oh, Do-Youn, MD and Strosberg, Jonathan, MD and Kulke, Matthew H, MD and Pavel, Marianne E, MD and RAD001 Adv Neuroendocrine Tumours and Fourth Trial RADIANT-4 Study Grp and RAD001 in Advanced Neuroendocrine Tumours, Fourth Trial (RADIANT-4) Study Group
Lancet, The, ISSN 0140-6736, 2015, Volume 387, Issue 10022, pp. 968 - 977
Summary Background Effective systemic therapies for patients with advanced, progressive neuroendocrine tumours of the lung or gastrointestinal tract are... 
Internal Medicine | SUNITINIB | MEDICINE, GENERAL & INTERNAL | MUTATIONS | Lung Neoplasms - drug therapy | Double-Blind Method | Gastrointestinal Neoplasms - drug therapy | Gastrointestinal Neoplasms - mortality | Lung Neoplasms - mortality | Humans | Middle Aged | Male | Treatment Outcome | Antineoplastic Agents - therapeutic use | Young Adult | Neuroendocrine Tumors - mortality | Survival Analysis | Aged, 80 and over | Neuroendocrine Tumors - drug therapy | Adult | Everolimus - therapeutic use | Female | Aged | Care and treatment | Angiogenesis inhibitors | Gastrointestinal system | Tumors | Analysis | Nervous system | Chemotherapy | Metastasis | Endocrine system | Medical prognosis | Index Medicus | Abridged Index Medicus
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8. Full Text Association of Cigarette, Cigar, and Pipe Use With Mortality Risk in the US Population
by Christensen, Carol H and Rostron, Brian and Cosgrove, Candace and Altekruse, Sean F and Hartman, Anne M and Gibson, James T and Apelberg, Benjamin and Inoue-Choi, Maki and Freedman, Neal D
JAMA Internal Medicine, ISSN 2168-6106, 04/2018, Volume 178, Issue 4, pp. 469 - 476
IMPORTANCE: Tobacco products have changed in recent years. Contemporary mortality risk estimates of combustible tobacco product use are needed. OBJECTIVE: To... 
UNITED-STATES | MEDICINE, GENERAL & INTERNAL | SMOKING | TOBACCO | Pulmonary Disease, Chronic Obstructive - mortality | United States - epidemiology | Cigarette Smoking - epidemiology | Pancreatic Neoplasms - epidemiology | Gastrointestinal Neoplasms - mortality | Lung Neoplasms - mortality | Humans | Middle Aged | Male | Pulmonary Disease, Chronic Obstructive - epidemiology | Gastrointestinal Neoplasms - epidemiology | Head and Neck Neoplasms - epidemiology | Aged, 80 and over | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Adult | Female | Pancreatic Neoplasms - mortality | Urinary Bladder Neoplasms - epidemiology | Cigar Smoking - epidemiology | Urinary Bladder Neoplasms - mortality | Mortality | Proportional Hazards Models | Neoplasms - mortality | Pipe Smoking - epidemiology | Lung Neoplasms - epidemiology | Aged | Head and Neck Neoplasms - mortality | Longitudinal Studies | Neoplasms - epidemiology | Cohort Studies | Index Medicus | Abridged Index Medicus | Online First | Original Investigation | Research
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9. Full Text Metastatic Melanoma to the Colon, Rectum, and Anus: A 50-Year Experience
by Park, Jin-soo and Ng, Kheng-Seong and Saw, Robyn P. M and Thompson, John F and Young, Christopher J
Annals of Surgical Oncology, ISSN 1068-9265, 8/2018, Volume 25, Issue 8, pp. 2178 - 2183
Melanoma metastatic to the large bowel (colon, rectum, and anus) is rarely diagnosed, with more than 95% of large bowel metastases identified post-mortem. The... 
Oncology | Medicine & Public Health | Surgical Oncology | Surgery | SURGERY | MALIGNANT-MELANOMA | PATTERN | ONCOLOGY | GASTROINTESTINAL-TRACT | Melanoma - epidemiology | Prognosis | Follow-Up Studies | Humans | Middle Aged | Anus Neoplasms - surgery | Male | Rectal Neoplasms - epidemiology | Incidence | Colonic Neoplasms - surgery | Time Factors | Skin Neoplasms - mortality | Female | Rectal Neoplasms - pathology | Anus Neoplasms - epidemiology | Skin Neoplasms - surgery | Colonic Neoplasms - mortality | Rectal Neoplasms - surgery | Colonic Neoplasms - epidemiology | Survival Rate | Anus Neoplasms - pathology | Skin Neoplasms - epidemiology | Australia - epidemiology | Melanoma - secondary | Rectal Neoplasms - mortality | Colonic Neoplasms - pathology | Anus Neoplasms - mortality | Skin Neoplasms - secondary | Melanoma - surgery | Melanoma - mortality | Melanoma | Metastasis | Index Medicus
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10. Full Text Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Improves Survival of Patients with Peritoneal Carcinomatosis from Gastric Cancer: Final Results of a Phase III Randomized Clinical Trial
by Yang, Xiao-Jun and Huang, Chao-Qun and Suo, Tao and Mei, Lie-Jun and Yang, Guo-Liang and Cheng, Fu-Lin and Zhou, Yun-Feng and Xiong, Bin and Yonemura, Yutaka and Li, Yan
Annals of Surgical Oncology, ISSN 1068-9265, 6/2011, Volume 18, Issue 6, pp. 1575 - 1581
This randomized phase III study was to evaluate the efficacy and safety of cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC)... 
Oncology | Medicine & Public Health | Surgical Oncology | Surgery | SURGERY | MALIGNANCY | MANAGEMENT | MORBIDITY | ONCOLOGY | MITOMYCIN-C | DISSEMINATION | PERFUSION | FUTURE | STRATEGIES | Prospective Studies | Humans | Middle Aged | Male | Stomach Neoplasms - pathology | Cisplatin - administration & dosage | Young Adult | Carcinoma, Squamous Cell - mortality | Hyperthermia, Induced | Adult | Female | Chemotherapy, Adjuvant | Adenocarcinoma, Mucinous - therapy | Peritoneal Neoplasms - secondary | Injections, Intraperitoneal | Stomach Neoplasms - therapy | Carcinoma, Squamous Cell - therapy | Survival Rate | Treatment Outcome | Adenocarcinoma, Mucinous - secondary | Combined Modality Therapy | Peritoneal Neoplasms - mortality | Adenocarcinoma - secondary | Adenocarcinoma, Mucinous - mortality | Adenocarcinoma - therapy | Carcinoma, Signet Ring Cell - mortality | Carcinoma, Signet Ring Cell - secondary | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Carcinoma, Squamous Cell - secondary | Aged | Carcinoma, Signet Ring Cell - therapy | Neoplasm Staging | Mitomycin - administration & dosage | Peritoneal Neoplasms - therapy | Stomach Neoplasms - mortality | Chemotherapy, Cancer, Regional Perfusion | Adenocarcinoma - mortality | Mitomycin | Patient outcomes | Oncology, Experimental | Clinical trials | Product development | Research | Stomach cancer | Cancer | Index Medicus | Gastrointestinal Oncology
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11. Full Text Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy
by Eggermont, Alexander M.M and Chiarion-Sileni, Vanna and Grob, Jean-Jacques and Dummer, Reinhard and Wolchok, Jedd D and Schmidt, Henrik and Hamid, Omid and Robert, Caroline and Ascierto, Paolo A and Richards, Jon M and Lebbé, Céleste and Ferraresi, Virginia and Smylie, Michael and Weber, Jeffrey S and Maio, Michele and Bastholt, Lars and Mortier, Laurent and Thomas, Luc and Tahir, Saad and Hauschild, Axel and Hassel, Jessica C and Hodi, F. Stephen and Taitt, Corina and de Pril, Veerle and de Schaetzen, Gaetan and Suciu, Stefan and Testori, Alessandro
The New England Journal of Medicine, ISSN 0028-4793, 11/2016, Volume 375, Issue 19, pp. 1845 - 1855
Patients with surgically resected stage III melanoma are at high risk for recurrence. The 5-year survival rate with ipulimumab was 11 percentage points higher... 
HIGH-RISK MELANOMA | TRIAL | METASTATIC MELANOMA | MEDICINE, GENERAL & INTERNAL | INTERFERON-ALPHA | MULTICENTER | METAANALYSIS | ULCERATION | TUMOR BURDEN | CUTANEOUS MELANOMA | NODE-POSITIVE MELANOMA | Skin Neoplasms - drug therapy | Humans | Ipilimumab | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Adjuvants, Immunologic - adverse effects | Young Adult | Skin Neoplasms - mortality | Melanoma - drug therapy | Adolescent | Survival Analysis | Aged, 80 and over | Adult | Female | Aged | Melanoma - surgery | Neoplasm Staging | Adjuvants, Immunologic - therapeutic use | Skin Neoplasms - surgery | Gastrointestinal Diseases - chemically induced | Gastrointestinal Diseases - immunology | Melanoma - mortality | Complications and side effects | Usage | Analysis | Melanoma | Adjuvant treatment | Clinical trials | Research | Cancer | Chemotherapy | Immune checkpoint | Risk groups | Body weight | Death | Survival | Drug dosages | Clinical outcomes | Metastases | Index Medicus | Abridged Index Medicus
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12. Full Text Prognostic value of tumor-infiltrating FoxP3+ T cells in gastrointestinal cancers: A meta analysis
by Huang, Yong and Liao, Huaiwei and Zhang, Yong and Yuan, Rongfa and Wang, Fengmei and Gao, Yingtang and Wang, Peng and Du, Zhi
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, pp. e94376 - e94376
Purpose: Tumor-infiltrating FoxP3(+) T cells have been reported in various human tumors, which impaired cell-mediated immunity and promoted disease... 
SURVIVAL | HEPATOCELLULAR-CARCINOMA | GASTRIC-CANCER | CLINICAL IMPACT | COLORECTAL-CANCER | POOR-PROGNOSIS | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | RECURRENCE | ADVERSE PROGNOSIS | EXPRESSION | Carcinoma, Hepatocellular - mortality | Prognosis | Colorectal Neoplasms - genetics | Humans | Male | Stomach Neoplasms - pathology | Liver Neoplasms - mortality | Neoplasm Recurrence, Local - mortality | Colorectal Neoplasms - diagnosis | Neoplasm Recurrence, Local - pathology | Forkhead Transcription Factors - metabolism | Carcinoma, Hepatocellular - genetics | Female | Liver Neoplasms - pathology | Lymphocytes, Tumor-Infiltrating - metabolism | Odds Ratio | Colorectal Neoplasms - mortality | Stomach Neoplasms - genetics | Gene Expression | Stomach Neoplasms - diagnosis | Liver Neoplasms - genetics | Carcinoma, Hepatocellular - diagnosis | Neoplasm Recurrence, Local - diagnosis | Forkhead Transcription Factors - genetics | Liver Neoplasms - diagnosis | Lymphocytes, Tumor-Infiltrating - pathology | Carcinoma, Hepatocellular - pathology | Survival Analysis | Neoplasm Recurrence, Local - genetics | Colorectal Neoplasms - pathology | Stomach Neoplasms - mortality | Laboratories | Colorectal carcinoma | Colorectal cancer | Clinical trials | Hepatocellular carcinoma | Systematic review | Lymphocytes T | Immunity | Stomach cancer | Immunity (cell-mediated) | Metastases | Confidence intervals | Liver cancer | Lymphocytes | Hepatology | Surgery | Foxp3 protein | Gastric cancer | Cell survival | Patients | Survival | Studies | Hospitals | Medical prognosis | Infiltration | Tumors | Cancer | Index Medicus
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