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CANCER RESEARCH, ISSN 0008-5472, 06/2013, Volume 73, Issue 12, pp. 3499 - 3510
Cancer immunosurveillance relies on effector/memory tumor-infiltrating CD8(+) T cells with a T-helper cell 1 (T(H)1) profile. Evidence for a natural killer... 
NATURAL-KILLER-CELLS | INHIBITION | EFFICACY | ONCOLOGY | C-KIT | MUTATIONS | CYTOTOXIC ACTIVITY | CANCER | EXPRESSION | IMATINIB MESYLATE | PREDICTION | Forkhead Transcription Factors - immunology | Immunohistochemistry | Multivariate Analysis | Pyrimidines - immunology | Prognosis | Humans | Middle Aged | Male | Benzamides - therapeutic use | Flow Cytometry | T-Lymphocytes - metabolism | Forkhead Transcription Factors - metabolism | Protein Kinase Inhibitors - immunology | T-Lymphocytes - drug effects | Aged, 80 and over | Killer Cells, Natural - immunology | Adult | Female | Lymphocytes, Tumor-Infiltrating - metabolism | CD56 Antigen - immunology | Natural Cytotoxicity Triggering Receptor 1 - immunology | Gastrointestinal Stromal Tumors - immunology | CD56 Antigen - metabolism | Kaplan-Meier Estimate | Treatment Outcome | Piperazines - therapeutic use | Lymphocytes, Tumor-Infiltrating - drug effects | Benzamides - immunology | CD3 Complex - metabolism | Imatinib Mesylate | Gastrointestinal Stromal Tumors - drug therapy | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | CD3 Complex - immunology | Piperazines - immunology | Gastrointestinal Stromal Tumors - metabolism | Natural Cytotoxicity Triggering Receptor 1 - metabolism | T-Lymphocytes - immunology | Aged | Killer Cells, Natural - drug effects | Killer Cells, Natural - metabolism | Cohort Studies | Lymphocytes, Tumor-Infiltrating - immunology
Journal Article
Nature Medicine, ISSN 1078-8956, 09/2011, Volume 17, Issue 9, pp. 1094 - 1100
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 02/2008, Volume 32, Issue 2, pp. 210 - 218
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 01/2017, Volume 23, Issue 2, pp. 454 - 465
Purpose: Tyrosine kinase inhibitors are effective in gastrointestinal stromal tumors (GISTs) but often are of transient benefit as resistance commonly... 
ACTIVATION | ANTI-PD-L1 ANTIBODY | INHIBITION | ONCOLOGY | SAFETY | PD-L1 EXPRESSION | KIT | RESISTANCE | MELANOMA PATIENTS | CANCER | RECEPTOR TYROSINE KINASE | Humans | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Molecular Targeted Therapy | STAT1 Transcription Factor - genetics | B7-H1 Antigen - immunology | STAT1 Transcription Factor - antagonists & inhibitors | Xenograft Model Antitumor Assays | Gastrointestinal Stromal Tumors - therapy | Animals | B7-H1 Antigen - antagonists & inhibitors | Antibodies, Monoclonal - administration & dosage | Lymphocyte Activation - drug effects | T-Lymphocytes - drug effects | Gastrointestinal Stromal Tumors - pathology | Immunotherapy | Imatinib Mesylate - administration & dosage | Cell Line, Tumor | T-Lymphocytes - immunology | Mice | Gene Expression Regulation, Neoplastic - drug effects | Programmed Cell Death 1 Receptor - immunology | Gastrointestinal Stromal Tumors - genetics | Antibodies, Monoclonal - immunology | Gastrointestinal Stromal Tumors - immunology | Flow cytometry | PD-1 protein | Lymphocytes T | Blood | Anticancer properties | Receptors | Cell activation | Lymphocytes | Inhibition | Stat1 protein | Protein-tyrosine kinase | Tyrosine | Imatinib | Tumor cells | T cell receptors | Gene expression | Cytometry | Mucin | Immune checkpoint | Experimental design | γ-Interferon | PD-L1 protein | Cell lines | Antitumor activity | Ligands | Tumors | Cancer | Apoptosis | PD-L1 | targeted therapy | PD-1 | immunotherapy | Gastrointestinal stromal tumor
Journal Article
Nature Immunology, ISSN 1529-2908, 08/2017, Volume 18, Issue 9, pp. 1004 - 1015
Journal Article
Cancer Research, ISSN 0008-5472, 04/2009, Volume 69, Issue 8, pp. 3563 - 3569
Journal Article
Journal Article
Journal Article
Nature Reviews Clinical Oncology, ISSN 1759-4774, 07/2016, Volume 13, Issue 7, pp. 431 - 446
Around 15 years ago, imatinib mesylate (Gleevec (R) or Glivec (R), Novartis, Switzerland) became the very first 'targeted' anticancer drug to be clinically... 
CHRONIC MYELOGENOUS LEUKEMIA | CYTOTOXIC T-CELLS | KILLER DENDRITIC CELLS | ONCOLOGY | MINOR HISTOCOMPATIBILITY ANTIGENS | HEMATOPOIETIC STEM-CELLS | ACUTE LYMPHOBLASTIC-LEUKEMIA | TYROSINE KINASE INHIBITOR | GASTROINTESTINAL STROMAL TUMORS | COMPLETE MOLECULAR RESPONSE | CHRONIC MYELOID-LEUKEMIA | Tumor Escape - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Antineoplastic Agents - therapeutic use | B7 Antigens - immunology | Drug Approval | Protein-Tyrosine Kinases - immunology | Hematopoiesis - drug effects | Natural Cytotoxicity Triggering Receptor 3 - drug effects | Imatinib Mesylate - therapeutic use | Immunity, Cellular - drug effects | Immune Tolerance - immunology | T-Lymphocytes - drug effects | Protein-Tyrosine Kinases - drug effects | Killer Cells, Natural - immunology | Molecular Chaperones - drug effects | Natural Cytotoxicity Triggering Receptor 3 - immunology | Vascular Endothelial Growth Factor A - drug effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - immunology | Molecular Chaperones - immunology | Molecular Targeted Therapy - methods | Gastrointestinal Stromal Tumors - immunology | Immune Tolerance - drug effects | Tumor Escape - immunology | Antigens, Neoplasm - immunology | Antineoplastic Agents - immunology | B7 Antigens - drug effects | Vascular Endothelial Growth Factor A - immunology | Immunologic Surveillance - drug effects | Forecasting | Immunologic Surveillance - immunology | Hematopoiesis - immunology | Imatinib Mesylate - immunology | Gastrointestinal Stromal Tumors - drug therapy | T-Lymphocytes - immunology | Killer Cells, Natural - drug effects | Antigens, Neoplasm - drug effects | Tyrosine | Care and treatment | Analysis | Immunotherapy | B cells | Drug approval | Cancer
Journal Article
International Journal of Cancer, ISSN 0020-7136, 08/2010, Volume 127, Issue 4, pp. 899 - 909
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 06/2017, Volume 23, Issue 12, pp. 2972 - 2980
Journal Article