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1. Full Text Histopathological effects of Pedunsaponin A on Pomacea canaliculata
by Yang, Chunping and Yang, Song and Tian, Yue and Lv, Tianxing and Chang, Xiaoli and Zhang, Min and Gong, Guoshu and Zhao, Liulan and Chen, Huabao
Pesticide Biochemistry and Physiology, ISSN 0048-3575, 06/2018, Volume 148, pp. 151 - 158
Pedunsaponin A, a novel molluscicidal compound isolated from , exhibits strong toxicity against . To determine the mechanisms of Pedunsaponin A toxicity, its... 
Histopathological effects | Hemolymph | Pueraria peduncularis | Pedunsaponin A | Pomacea canaliculata | Cilia | PHYSIOLOGY | HEMOCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOLLUSCICIDAL ACTIVITY | ENTOMOLOGY | Hemocytes - physiology | Triterpenes - toxicity | Kidney - pathology | Hemolymph - drug effects | Hepatopancreas - pathology | Gastropoda - physiology | Gills - drug effects | Pericardium - pathology | Cilia - drug effects | Gastropoda - immunology | Gills - blood supply | Gills - pathology | Lung - pathology | Cilia - pathology | Kidney - drug effects | Hepatopancreas - drug effects | Gastropoda - drug effects | Pericardium - drug effects | Mitochondria - drug effects | Saponins - toxicity | Animals | Hemocytes - drug effects | Lung - drug effects | Blood Vessels - drug effects | Ribosomes - drug effects | Lung - blood supply | Molluscacides - toxicity
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2. Full Text In situ gelling systems based on Pluronic F127/Pluronic F68 formulations for ocular drug delivery
by Al Khateb, Kosai and Ozhmukhametova, Elvira K and Mussin, Marat N and Seilkhanov, Serzhan K and Rakhypbekov, Tolebai K and Lau, Wing Man and Khutoryanskiy, Vitaliy V
International Journal of Pharmaceutics, ISSN 0378-5173, 04/2016, Volume 502, Issue 1-2, pp. 70 - 79
This study evaluated the use of Pluronic F127 and Pluronic F68 as excipients for formulating gelling systems for ocular drug delivery. Thermal transitions have... 
Pluronics | Mucoadhesion | Ocular drug delivery | Gelation | In situ gelling systems | MUCOADHESIVE | POLYMERS | HYDROGELS | SOLUBILIZATION | COMPLEXES | COPOLYMERS | POLY(ACRYLIC ACID) | NANOPARTICLES | TEMPERATURE | PHARMACOLOGY & PHARMACY | Eye - metabolism | Poloxamer - chemistry | Administration, Ophthalmic | Rabbits | Gels | Gastropoda - metabolism | Rheology | Gastropoda - drug effects | Chemistry, Pharmaceutical | Drug Delivery Systems | Mucous Membrane - metabolism | Poloxamer - toxicity | Animals | Poloxamer - pharmacology | Excipients - chemistry | Excipients - toxicity | Cattle | Micelles | Excipients - pharmacology | Mucus - metabolism | Eye - drug effects | Mucous Membrane - drug effects | Drugs | Drug delivery systems | Ophthalmic drugs | Vehicles
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3. Full Text Acute toxicity of 8 antidepressants: What are their modes of action?
by Minguez, Laetitia and Farcy, Emilie and Ballandonne, Céline and Lepailleur, Alban and Serpentini, Antoine and Lebel, Jean-Marc and Bureau, Ronan and Halm-Lemeille, Marie-Pierre
Chemosphere, ISSN 0045-6535, 08/2014, Volume 108, pp. 314 - 319
Currently, the hazard posed by pharmaceutical residues is a major concern of ecotoxicology. Most of the antidepressants belong to a family named the Cationic... 
Multi-approach | Pharmaceutical | Haliotis tuberculata | Narcosis | Lysosomotropism | Daphnia magna | HUMAN PHARMACEUTICALS | ECOTOXICOLOGY | FLUOXETINE | CELL-CULTURES | ENVIRONMENTAL SCIENCES | CAUSE FOOT DETACHMENT | HEMOCYTES | PI INTERACTIONS | CYTOTOXICITY ASSESSMENT | CATIONIC AMPHIPHILIC DRUGS | WATER | Lysosomes - drug effects | Cell Survival - drug effects | Gastropoda - drug effects | Serotonin Uptake Inhibitors - toxicity | Cells, Cultured | Gastropoda - cytology | Models, Molecular | Phosphatidylcholines - metabolism | Antidepressive Agents - toxicity | Daphnia - metabolism | Daphnia - drug effects | Animals | Lysosomes - metabolism | Hemocytes - drug effects | Environmental Pollutants - toxicity | Hemocytes - cytology | Antidepressants, Tricyclic | Index Medicus | Environmental Sciences
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4. Full Text Ecotoxicological characterization of the antiepileptic drug carbamazepine using eight aquatic species: baseline study for future higher tier tests
by Heye, Katharina and Wiebusch, Janina and Becker, Johannes and Rongstock, Lydia and Bröder, Kathrin and Wick, Arne and Schulte-Oehlmann, Ulrike and Oehlmann, Jörg
Journal of Environmental Science and Health, Part A, ISSN 1093-4529, 04/2019, Volume 54, Issue 5, pp. 441 - 451
Ecotoxicological effects of the antiepileptic drug carbamazepine (CBZ) were investigated in one primary producer (Desmodesmus subspicatus) and seven... 
hazard | algae | risk | Chironomus | Ceriodaphnia | Pharmaceutical | chronic | Daphnia; Potamopyrgus; Lumbriculus | PERSONAL CARE PRODUCTS | ENVIRONMENTAL CONCENTRATIONS | EBRO RIVER-BASIN | CHRONIC TOXICITY | Lumbriculus | TRANSFORMATION PRODUCTS | CHIRONOMUS-RIPARIUS DIPTERA | ENVIRONMENTAL SCIENCES | PHARMACEUTICAL RESIDUES | ENGINEERING, ENVIRONMENTAL | Daphnia | LIFE-HISTORY | DAPHNIA-MAGNA | Potamopyrgus | HYALELLA-AZTECA | Carbamazepine - analysis | Ecotoxicology | Species Specificity | Gastropoda - drug effects | Water Pollutants, Chemical - analysis | Anticonvulsants - toxicity | No-Observed-Adverse-Effect Level | Daphnia - drug effects | Toxicity Tests, Chronic | Animals | Anticonvulsants - analysis | Water Pollutants, Chemical - toxicity | Aquatic Organisms - drug effects | Oligochaeta - drug effects | Carbamazepine - toxicity | Chironomidae - drug effects | Amphipoda - drug effects | Cladocera - drug effects | Water-borne diseases | Ecological effects | Chronic toxicity | Toxicity testing | Biting | Invertebrates | Hazard assessment | Antiepileptic agents | Species | Environmental risk | Carbamazepine
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5. Full Text Deriving the freshwater quality criteria of BPA, BPF and BPAF for protecting aquatic life
by Wang, Zhen and Wang, Lei and Liu, Jining and Ji, Guixiang and Shi, Lili and Xu, Jing and Yang, Jiaxin
Ecotoxicology and Environmental Safety, ISSN 0147-6513, 11/2018, Volume 164, pp. 713 - 721
Bisphenol A (BPA) has been recognized by the European Chemicals Agency (ECHA) as an endocrine disruptor, and its use in thermo paper has been restricted from... 
Species sensitivity distribution | BPF | BPA | BPAF | Water quality criteria | ENDOCRINE-DISRUPTING CHEMICALS | ANALOGS | CHINA | TOXICITY | RIVER | 17-ALPHA-ETHINYLESTRADIOL | ENVIRONMENTAL SCIENCES | HUMAN EXPOSURE | BISPHENOL-A | TOXICOLOGY | SPECIES SENSITIVITY DISTRIBUTIONS | SURFACE WATERS | Scenedesmus - drug effects | Risk Assessment | Benzhydryl Compounds - toxicity | Phenols - toxicity | Gastropoda - drug effects | Snails - drug effects | Fresh Water - chemistry | Lakes - chemistry | Lethal Dose 50 | Water Quality | No-Observed-Adverse-Effect Level | Daphnia - drug effects | Phenols - analysis | Toxicity Tests, Chronic | Animals | Rivers - chemistry | Zebrafish - metabolism | Endpoint Determination | Chironomidae - drug effects | Chlorophyta - drug effects | Benzhydryl Compounds - analysis | Water | Management | Rivers | Index Medicus
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6. Full Text Whole effluent toxicity assessment at a wastewater treatment plant upgraded with a full-scale post-ozonation using aquatic key species
by Magdeburg, Axel and Stalter, Daniel and Oehlmann, Jörg
Chemosphere, ISSN 0045-6535, 08/2012, Volume 88, Issue 8, pp. 1008 - 1014
â–º Ozonation of effluents with no immediate beneficial effect on toxicity endpoints. â–º Increased toxicity after ozonation was apparent in three out of five test... 
Endocrine disruption | Emerging contaminants | Estrogenicity | Advanced oxidation process | Oxidation byproducts | PHARMACEUTICALS | CARBAMAZEPINE | METOPROLOL | FILTRATION | ENVIRONMENTAL SCIENCES | TRANSPORT | REMOVAL | ADVANCED OXIDATION PROCESSES | PRODUCTS | INVERTEBRATES | DRINKING-WATER | Daphnia - drug effects | Animals | Water Pollutants, Chemical - toxicity | Oxidation-Reduction | Gastropoda - drug effects | Oligochaeta - drug effects | Ozone - chemistry | Chironomidae - drug effects | Araceae - drug effects | Waste Disposal, Fluid | Toxicity Tests | Ozonization | Sewage | Purification | Water treatment plants | Index Medicus
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7. Full Text Mediterranean essential oils as effective weapons against the West Nile vector Culex pipiens and the Echinostoma intermediate host Physella acuta: what happens around? An acute toxicity survey on non-target mayflies
by Benelli, Giovanni and Bedini, Stefano and Flamini, Guido and Cosci, Francesca and Cioni, Pier Luigi and Amira, Smain and Benchikh, Fatima and Laouer, Hocine and Di Giuseppe, Graziano and Conti, Barbara
Parasitology Research, ISSN 0932-0113, 3/2015, Volume 114, Issue 3, pp. 1011 - 1021
Mosquitoes (Diptera: Culicidae) represent a threat for millions of people worldwide, since they act as vectors for important pathogens, including malaria,... 
Haplophyllum tuberculatum | Medical Microbiology | Mosquito-borne diseases | Biomedicine | Immunology | Microbiology | Achillea millefolium | Non-target aquatic organisms | GC-MS analysis | Echinostomiasis | Trematoda | INSECTICIDE RESISTANCE | HAPLOPHYLLUM-TUBERCULATUM | LARVICIDAL ACTIVITY | MARMORATA MOLLUSCA PHYSIDAE | CHEMICAL-COMPOSITION | AROMATIC PLANTS | HYPTIS-SPICIGERA LAM | BIOMPHALARIA-GLABRATA | AEDES | PARASITOLOGY | SNAIL | Monoterpenes - isolation & purification | Oils, Volatile - chemistry | Gastropoda - drug effects | Monoterpenes - toxicity | Echinostoma - drug effects | Lethal Dose 50 | Culicidae - drug effects | Gastropoda - parasitology | Animals | Ephemeroptera - drug effects | Larva - drug effects | Culex - drug effects | Mediterranean Region | Oils, Volatile - toxicity | Control | Mosquitoes | Genetic vectors | West Nile virus | Mollusks | Essences and essential oils | Health aspects | Methods | Index Medicus
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8. Full Text Metabolomic responses of Haliotis diversicolor to organotin compounds
by Lu, Jie and Feng, Jianghua and Cai, Shuhui and Chen, Zhong
Chemosphere, ISSN 0045-6535, 02/2017, Volume 168, pp. 860 - 869
Organotin compounds, especially tributyltin (TBT) and triphenyltin (TPT), are a group of hazardous pollutants in marine environments. is an important marine... 
Organotin compounds | Metabolomics | Gill | Haliotis diversicolor | Hepatopancreas | TBT | MARINE MUSSEL | ENVIRONMENTAL SCIENCES | POLLUTION | ABALONE | DISCUS-HANNAI INO | IMPOSEX | MUSSEL MYTILUS-GALLOPROVINCIALIS | NMR-BASED METABOLOMICS | CLAM RUDITAPES-PHILIPPINARUM | EXPOSURE | Trialkyltin Compounds - pharmacology | Hepatopancreas - drug effects | Magnetic Resonance Spectroscopy | Organotin Compounds - pharmacology | Gastropoda - metabolism | Gastropoda - drug effects | Gills - metabolism | Male | Metabolomics - methods | Gills - drug effects | Animals | Hepatopancreas - metabolism | Oxidative Stress - drug effects | Energy Metabolism - drug effects | Metabolites | Analysis | Amino acids | Nuclear magnetic resonance spectroscopy | Tributyltin | Tributylin | Glutamate | Lysine | Glycine | Index Medicus
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9. Full Text Antifouling and toxic properties of the bioactive metabolites from the seagrasses Syringodium isoetifolium and Cymodocea serrulata
by Iyapparaj, Palanisamy and Revathi, Peranandam and Ramasubburayan, Ramasamy and Prakash, Santhiyagu and Palavesam, Arunachalam and Immanuel, Grasian and Anantharaman, Perumal and Sautreau, Asmita and Hellio, Claire
Ecotoxicology and Environmental Safety, ISSN 0147-6513, 05/2014, Volume 103, Issue 1, pp. 54 - 60
The present study documents the antifouling and toxic properties of seagrasses and . For that, the seagrasses and were extracted individually using organic... 
GC–MS | Seagrass | Bioassay | Fatty acids | Biofouling | Antifouling substances | GC-MS | SECONDARY METABOLITES | BOOSTER BIOCIDES | MARINE-BACTERIA | MICROORGANISMS | ENVIRONMENTAL SCIENCES | INHIBITION | NATURAL-PRODUCT ANTIFOULANTS | ANTIBACTERIAL ACTIVITY | GROWTH | TOXICOLOGY | EXTRACTS | Plant Extracts - chemistry | Gas Chromatography-Mass Spectrometry | Plant Extracts - toxicity | Microalgae - drug effects | Gastropoda - drug effects | Bacteria - drug effects | Chromatography, Thin Layer | Biota - drug effects | Microbial Sensitivity Tests | Artemia - drug effects | Animals | Pesticides - toxicity | Pesticides - chemistry | Biological Assay | Methanol - chemistry | Alismatales - chemistry | Perna - drug effects | Metabolites | Analysis | Mortality | Marine biology | Bacteria | Mass spectrometry | Chromatography | Index Medicus
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10. Full Text Antioxidant responses in estuarine invertebrates exposed to repeated oil spills: Effects of frequency and dosage in a field manipulative experiment
by Sandrini-Neto, Leonardo and Pereira, Letícia and Martins, César C and Silva de Assis, Helena C and Camus, Lionel and Lana, Paulo C
Aquatic Toxicology, ISSN 0166-445X, 08/2016, Volume 177, pp. 237 - 249
We have experimentally investigated the effects of repeated diesel spills on the bivalve , the gastropod and the polychaete , by monitoring the responses of... 
Biomarkers | Paranaguá bay | Oxidative stress | Diesel | Polycyclic aromatic hydrocarbons | Field experiment | NEREIS-DIVERSICOLOR | CRASSOSTREA-GIGAS | POLYCYCLIC AROMATIC-HYDROCARBONS | GLUTATHIONE-PEROXIDASE | MYTILUS-GALLOPROVINCIALIS | Paranagua bay | OXIDATIVE STRESS BIOMARKERS | MULTIBIOMARKER APPROACH | POLLUTION BIOMARKERS | MARINE & FRESHWATER BIOLOGY | TOXICOLOGY | MYTELLA-GUYANENSIS | Biomarkers - metabolism | Gastropoda - metabolism | Antioxidants - metabolism | Gastropoda - drug effects | Random Allocation | Polychaeta - drug effects | Dose-Response Relationship, Drug | Animals | Water Pollutants, Chemical - toxicity | Polychaeta - metabolism | Brazil | Petroleum - toxicity | Water Pollution, Chemical - adverse effects | Bivalvia - metabolism | Oxidative Stress - drug effects | Bivalvia - drug effects | Toxicity Tests | Petroleum Pollution - adverse effects | Antioxidants | Estuaries | Oil spills | Index Medicus
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11. Full Text Negative effects of microplastic exposure on growth and development of Crepidula onyx
by Lo, Hau Kwan Abby and Chan, Kit Yu Karen
Environmental Pollution, ISSN 0269-7491, 02/2018, Volume 233, pp. 588 - 595
Microplastics exposure could be detrimental to marine organisms especially under high concentrations. However, few studies have considered the multiphasic... 
Carryover effect | Selective feeding | Gastropod | Veliger | Slipper limpet | SIZE | OCEAN ACIDIFICATION | ENVIRONMENTAL SCIENCES | CALYPTRAEIDAE | MUSSELS MYTILUS-EDULIS | FILTRATION-RATE | METAMORPHOSIS | SEX-CHANGE | LARVAL GROWTH | REPRODUCTION | FORNICATA | Animals | Water Pollutants, Chemical - toxicity | Larva - drug effects | Plastics - toxicity | Polystyrenes - toxicity | Aquatic Organisms | Gastropoda - growth & development
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12. Full Text Assessment of cytotoxic and immunomodulatory properties of four antidepressants on primary cultures of abalone hemocytes (Haliotis tuberculata)
by Minguez, Laetitia and Halm-Lemeille, Marie-Pierre and Costil, Katherine and Bureau, Ronan and Lebel, Jean-Marc and Serpentini, Antoine
Aquatic Toxicology, ISSN 0166-445X, 08/2014, Volume 153, pp. 3 - 11
Pharmaceutical compounds like antidepressants found in surface waters raise concerns due to their potential toxicity on non-target aquatic organisms. This... 
Immune response | Hemocyte | Abalone | Pharmaceutical | In vitro | CRASSOSTREA-GIGAS | DIGESTIVE CELLS | CHRONIC TOXICITY | PHAGOCYTIC-ACTIVITY | USEFUL TOOL | SEROTONIN REUPTAKE INHIBITORS | INTEGRATED BIOMARKER RESPONSE | CAUSE FOOT DETACHMENT | WASTE-WATER | MARINE & FRESHWATER BIOLOGY | TOXICOLOGY | IN-VITRO EXPOSURE | Cell Survival - drug effects | Phagocytosis - drug effects | Reactive Oxygen Species - metabolism | Immunity, Innate - drug effects | Hemocytes - enzymology | Gastropoda - drug effects | Cells, Cultured | Esterases - metabolism | Lethal Dose 50 | Enzyme Activation - drug effects | Antidepressive Agents - toxicity | Animals | Water Pollutants, Chemical - toxicity | Gastropoda - enzymology | Hemocytes - drug effects | Gastropoda - immunology | Serotonin uptake inhibitors | Analysis | Antidepressants, Tricyclic | Index Medicus | Environmental Sciences
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