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Chemical Communications, ISSN 1359-7345, 4/2016, Volume 52, Issue 32, pp. 5497 - 5515
Lysosomal storage disorders (LSDs) are often caused by mutations that destabilize native folding and impair the trafficking of enzymes, leading to premature... 
Gangliosidosis, GM1 - metabolism | Molecular Mimicry | Carbohydrates - chemistry | Gaucher Disease - metabolism | Fabry Disease - metabolism | Humans | Molecular Chaperones - therapeutic use | Fabry Disease - drug therapy | Gangliosidosis, GM1 - drug therapy | Gaucher Disease - drug therapy | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Science Translational Medicine, ISSN 1946-6234, 09/2016, Volume 8, Issue 355, pp. 355ra118 - 355ra118
Journal Article
Journal Article
Journal Article
Journal Article
Annals of Neurology, ISSN 0364-5134, 11/2016, Volume 80, Issue 5, pp. 766 - 775
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2013, Volume 110, Issue 9, pp. 3537 - 3542
Mutations of GBA1, the gene encoding glucocerebrosidase, represent a common genetic risk factor for developing the synucleinopathies Parkinson disease (PD) and... 
Pathology | Enzymes | Gaucher disease | Lewy body disease | Central nervous system | Parkinson disease | Mice | Alzheimers disease | Genetic mutation | Dementia | Lysosomal storage diseases | Memory defect | MAPT | Mouse models | mouse models | TAU-SYNUCLEIN | lysosomal storage diseases | DEMENTIA | MULTIDISCIPLINARY SCIENCES | ALPHA-SYNUCLEIN | PATHOLOGY | CEREBROSPINAL-FLUID | DEFICIENCY | GENE | DISEASE | memory defect | MUTATIONS | LEWY BODIES | Glucosylceramidase - genetics | Humans | Memory | Brain - enzymology | tau Proteins - metabolism | Gaucher Disease - pathology | tau Proteins - chemistry | Psychosine - analogs & derivatives | Parkinsonian Disorders - drug therapy | Protein Structure, Quaternary | Gaucher Disease - physiopathology | alpha-Synuclein - genetics | Gaucher Disease - drug therapy | Disease Models, Animal | Gaucher Disease - enzymology | Parkinsonian Disorders - physiopathology | Dependovirus - metabolism | Brain - physiopathology | Psychosine - metabolism | Mice, Transgenic | Parkinsonian Disorders - enzymology | Glucosylceramidase - metabolism | Hippocampus - pathology | Hippocampus - metabolism | Animals | Glucosylceramidase - therapeutic use | Brain - pathology | Glucosylceramidase - administration & dosage | Hippocampus - physiopathology | alpha-Synuclein - metabolism | Parkinsonism | Care and treatment | Physiological aspects | Hydrolases | Gaucher's disease | Nervous system | Mutation | Risk factors | Parkinsons disease | Index Medicus | Biological Sciences
Journal Article
Journal Article