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Drug Metabolism and Disposition, ISSN 0090-9556, 08/2007, Volume 35, Issue 8, pp. 1308 - 1314
Hepatic uptake carriers of the organic anion-transporting peptide (OATP) family of solute carriers are more and more recognized as being involved in hepatic... 
RAT | SEVERE RHABDOMYOLYSIS | COMBINATION THERAPY | LIVER | PHARMACOLOGY & PHARMACY | CERIVASTATIN | HEPATIC-UPTAKE | TRANSPLANT RECIPIENTS | ROSUVASTATIN | POLYPEPTIDE | FAMILY | Organic Anion Transporters, Sodium-Independent - genetics | Fatty Acids, Monounsaturated - pharmacology | Cricetulus | Hypolipidemic Agents - metabolism | Hypoglycemic Agents - metabolism | Taurocholic Acid - metabolism | Humans | Hepatocytes - metabolism | Simvastatin - pharmacology | Organic Anion Transporters - metabolism | Chromans - metabolism | Hepatocytes - cytology | Indoles - metabolism | Organic Anion Transporters - genetics | Drug Interactions | Anticholesteremic Agents - metabolism | Chromans - pharmacology | Fatty Acids, Monounsaturated - metabolism | Organic Anion Transporters, Sodium-Independent - metabolism | Indoles - pharmacology | Biological Transport - drug effects | Thiazolidinediones - pharmacology | Hepatocytes - drug effects | Solute Carrier Organic Anion Transporter Family Member 1B3 | CHO Cells | Pravastatin - pharmacology | Recombinant Proteins - metabolism | Taurocholic Acid - pharmacology | Cell Line | Cricetinae | Pravastatin - metabolism | Simvastatin - metabolism | Gemfibrozil - pharmacokinetics | Gemfibrozil - pharmacology | Hypolipidemic Agents - pharmacology | Thiazolidinediones - metabolism | Hypoglycemic Agents - pharmacology | Animals | Estrone - analogs & derivatives | Estrone - metabolism | Protein Binding | Fatty Acids, Monounsaturated - pharmacokinetics | Indoles - pharmacokinetics | Kinetics | Solute Carrier Organic Anion Transporter Family Member 1b1 | Anticholesteremic Agents - pharmacology | Gemfibrozil - metabolism
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 04/2014, Volume 23, Issue 8, pp. 2005 - 2022
Neuronal ceroid lipofuscinosis (NCL) comprises 13 genetically distinct lysosomal disorders primarily affecting the central nervous system. Here we report... 
PLURIPOTENT STEM-CELLS | YEAST | MULTIVESICULAR BODY FORMATION | PROTEIN | ADENOASSOCIATED VIRUS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOUSE MODEL | ORTHOLOGUE | GENETICS & HEREDITY | BATTEN-DISEASE | BTN1 | TRIPEPTIDYL-PEPTIDASE | Serine Proteases - genetics | Neurons - pathology | Cell Proliferation | Molecular Chaperones - metabolism | Membrane Glycoproteins - metabolism | Golgi Apparatus - drug effects | Humans | Electrophysiology | Endoplasmic Reticulum - metabolism | Case-Control Studies | Immunoenzyme Techniques | Neuronal Ceroid-Lipofuscinoses - pathology | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - metabolism | Fenofibrate - pharmacology | Lysosomes - metabolism | Neuronal Ceroid-Lipofuscinoses - genetics | Endoplasmic Reticulum - drug effects | Neurons - metabolism | Neurons - drug effects | Aminopeptidases - metabolism | Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - genetics | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Induced Pluripotent Stem Cells - pathology | Lysosomes - drug effects | Serine Proteases - metabolism | Aminopeptidases - genetics | Induced Pluripotent Stem Cells - drug effects | Cells, Cultured | Molecular Chaperones - genetics | Neuronal Ceroid-Lipofuscinoses - metabolism | Gemfibrozil - pharmacology | Fibroblasts - pathology | Mutation - genetics | Blotting, Western | Membrane Glycoproteins - genetics | Fibroblasts - drug effects | Golgi Apparatus - metabolism | Models, Neurological | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2015, Volume 290, Issue 16, pp. 10309 - 10324
Lysosomes are ubiquitous membrane-enclosed organelles filled with an acidic interior and are central to the autophagic, endocytic, or phagocytic pathway. In... 
GEMFIBROZIL | GAMMA | Retinoic Acid | BIOCHEMISTRY & MOLECULAR BIOLOGY | Astrocyte | AUTOPHAGY | LIPID-LOWERING DRUG | Peroxisome proliferator-activated Receptor (PPAR) | MESSENGER-RNAS | ADOPTIVE TRANSFER | Neurodegeneration | GENE-EXPRESSION | Lysosomal Storage Disease | RETINOID-X-RECEPTOR | CELLULAR CLEARANCE | UP-REGULATION | Retinoid X Receptor alpha - metabolism | Humans | Neurons - cytology | PPAR gamma - metabolism | Autophagy - drug effects | Brain - metabolism | Lysosomes - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Neurons - metabolism | Neurons - drug effects | PPAR gamma - genetics | Tretinoin - pharmacology | Astrocytes - cytology | Lysosomes - drug effects | Astrocytes - drug effects | Promoter Regions, Genetic | Brain - cytology | PPAR-beta - metabolism | Signal Transduction | Gene Expression Regulation | PPAR alpha - genetics | Gemfibrozil - pharmacology | Transcription Factors - genetics | PPAR-beta - genetics | Brain - drug effects | Transcription Factors - metabolism | Animals | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Lipid Metabolism - drug effects | Retinoid X Receptor alpha - genetics | Protein Binding | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | PPAR alpha - agonists | Mice | PPAR alpha - metabolism | Primary Cell Culture | Astrocytes - metabolism
Journal Article
Water Science and Technology, ISSN 0273-1223, 2012, Volume 66, Issue 9, pp. 1856 - 1863
Emerging wastewater treatment processes such as membrane bioreactors (MBRs) have attracted a significant amount of interest internationally due to their... 
Pharmaceuticals and personal care products | Membrane bioreactor | Decentralised treatment system | Pesticides | Steroidal hormones | ESTROGENS | WASTE-WATER TREATMENT | MUNICIPAL SEWAGE | AUSTRALIA | steroidal hormones | PHARMACEUTICALS | pharmaceuticals and personal care products | WATER RESOURCES | decentralised treatment system | ENVIRONMENTAL SCIENCES | membrane bioreactor | ENGINEERING, ENVIRONMENTAL | pesticides | TREATMENT PLANTS | ENDOCRINE DISRUPTING COMPOUNDS | SYSTEMS | Pharmaceutical Preparations - isolation & purification | Omeprazole - metabolism | Diclofenac - isolation & purification | Diazepam - isolation & purification | Diazepam - metabolism | Organic Chemicals - metabolism | Trimethoprim - metabolism | Water Pollutants, Chemical - isolation & purification | Carbamazepine - metabolism | Sulfamethoxazole - metabolism | Organic Chemicals - isolation & purification | Amitriptyline - metabolism | Trimethoprim - isolation & purification | Gemfibrozil - isolation & purification | Sulfamethoxazole - isolation & purification | Water Pollutants, Chemical - metabolism | Amitriptyline - isolation & purification | Pharmaceutical Preparations - metabolism | Waste Disposal, Fluid - methods | Bioreactors | Fluoxetine - metabolism | Omeprazole - isolation & purification | Carbamazepine - isolation & purification | Gemfibrozil - metabolism | Diclofenac - metabolism | Fluoxetine - isolation & purification | Drugs | Removal | Organic contaminants | Trimethoprim | Hormones | Diclofenac | Waste water | Agrochemicals | Xenoestrogens | Recycling | Diazepam | Caffeine | Amitriptyline | Consumer products | Fluoxetine | Chemical wastewater | Chemical contaminants | Wastewater treatment | Carbamazepine | Omeprazole | Contaminants | Water reuse | Gemfibrozil | Water quality | Organic chemicals
Journal Article
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 01/2014, Volume 382, Issue 1, pp. 262 - 270
Glucose-sensing neurons play a role in energy homeostasis, yet how orexigenic neurons sense glucose remains unclear. As models of glucose-inhibited (GI)... 
Agouti-related peptide | AMPK | Glucose | Hypothalamus | Neuropeptide | ACTIVATED PROTEIN-KINASE | NITRIC-OXIDE SYNTHASE | ARCUATE NUCLEUS | NEUROPEPTIDE-Y | CELL BIOLOGY | TRANSMEMBRANE CONDUCTANCE REGULATOR | CHANNEL | EXTRACELLULAR GLUCOSE | ENDOCRINOLOGY & METABOLISM | NEURONS | RAT-BRAIN | EXPRESSION | Carnitine O-Palmitoyltransferase - genetics | Receptors, G-Protein-Coupled - metabolism | RNA, Messenger - metabolism | Adenylate Kinase - metabolism | Carnitine O-Palmitoyltransferase - metabolism | Deoxyglucose - pharmacology | Neurons - metabolism | Hypothalamus - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Pyruvic Acid - pharmacology | Neuropeptide Y | Cell Line | Green Fluorescent Proteins - metabolism | Hypothalamus - embryology | RNA, Messenger - genetics | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Glucose - pharmacology | Gemfibrozil - pharmacology | Down-Regulation - drug effects | Down-Regulation - genetics | Animals | Hypothalamus - metabolism | Agouti-Related Protein - biosynthesis | Hypothalamus - cytology | Models, Biological | Agouti-Related Protein - genetics | Nitric Oxide Synthase Type I - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Kinase - metabolism | Agouti-Related Protein - secretion | Mice | Receptors, G-Protein-Coupled - genetics | Glucose metabolism | Brain | Dextrose
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