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1. Full Text ZINC 15 – Ligand Discovery for Everyone
by Sterling, Teague and Irwin, John J
Journal of Chemical Information and Modeling, ISSN 1549-9596, 11/2015, Volume 55, Issue 11, pp. 2324 - 2337
Many questions about the biological activity and availability of small molecules remain inaccessible to investigators who could most benefit from their... 
CHEMISTRY, MEDICINAL | ASSAY | COMPUTER SCIENCE, INFORMATION SYSTEMS | IDENTIFICATION | MOLECULAR DOCKING | CHEMISTRY, MULTIDISCIPLINARY | HUMAN METABOLOME | UNICHEM | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS | DATABASE | CHEMISTRY | GENERATION | INHIBITORS | PROGRAM | Databases, Pharmaceutical | User-Computer Interface | Animals | Humans | Drug Discovery - methods | Ligands | Software | Internet | Genes - drug effects
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2. Full Text Metagenomic biomarker discovery and explanation
by Segata, Nicola and Izard, Jacques and Waldron, Levi and Gevers, Dirk and Miropolsky, Larisa and Garrett, Wendy S and Huttenhower, Curtis
Genome Biology, ISSN 1474-7596, 06/2011, Volume 12, Issue 6, pp. R60 - R60
This study describes and validates a new method for metagenomic biomarker discovery by way of class comparison, tests of biological consistency and effect size... 
CROHNS-DISEASE | GENE | DIET | PERSPECTIVE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MICROBIAL DIVERSITY | GENETICS & HEREDITY | CLASSIFICATION | GUT MICROBIOTA | MOUSE MODELS | GENOME-WIDE ASSOCIATION | RESOURCE | Method
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3. Knowledge discovery in bioinformatics
: techniques, methods, and applications
by Hu, Xiaohua and Pan, Yi
2007, Wiley Series in Bioinformatics, ISBN 9780471777960, xxi, 363 p., [16] p. of plates
The purpose of this edited book is to bring together the ideas and findings of data mining researchers and bioinformaticians by discussing... 
Electronics | Technology | General | Bioinformatics | Computational biology
Book
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4. Full Text Induced pluripotent stem cells - opportunities for disease modelling and drug discovery
by Grskovic, M and Javaherian, A and Strulovici, B and Daley, GQ
NATURE REVIEWS DRUG DISCOVERY, ISSN 1474-1776, 12/2011, Volume 10, Issue 12, pp. 915 - 929
The ability to generate induced pluripotent stem cells (iPSCs) from patients, and an increasingly refined capacity to differentiate these iPSCs into... 
MOTOR-NEURONS | SPINAL MUSCULAR-ATROPHY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | EPIGENETIC MEMORY | COPY NUMBER | GENE-EXPRESSION | EFFICIENT GENERATION | HUMAN FIBROBLASTS | PHARMACOLOGY & PHARMACY | LINEAGE-SPECIFIC DIFFERENTIATION | HUMAN SOMATIC-CELLS | IPS CELLS | Induced Pluripotent Stem Cells - pathology | Animals | Induced Pluripotent Stem Cells - drug effects | Humans | Cells, Cultured | Drug Discovery - trends | Nervous System Diseases - drug therapy | Drug Discovery - methods | Induced Pluripotent Stem Cells - cytology | Disease Models, Animal | Nervous System Diseases - pathology
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5. Full Text Target discovery
by Lindsay, Mark A
Nature Reviews Drug Discovery, ISSN 1474-1776, 10/2003, Volume 2, Issue 10, pp. 831 - 838
Target discovery, which involves the identification and early validation of disease-modifying targets, is an essential first step in the drug discovery... 
Animals | Oligonucleotide Array Sequence Analysis | Genomics | Humans | Drug Design | Gene Silencing | Proteomics | Gene Expression Profiling | RNA, Small Interfering | Drug Evaluation, Preclinical | Genome, Human | Disease Models, Animal | Pharmaceutical research | Protein research | Forecasts and trends | Drug approval
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6. Full Text Antibacterial drug discovery in the resistance era
by Brown, Eric D and Wright, Gerard D
Nature, ISSN 0028-0836, 01/2016, Volume 529, Issue 7586, pp. 336 - 343
The looming antibiotic-resistance crisis has penetrated the consciousness of clinicians, researchers, policymakers, politicians and the public at large. The... 
RESISTOME | ESSENTIAL GENES | STRUCTURAL BASIS | MULTIDISCIPLINARY SCIENCES | ANTIBIOTIC-RESISTANCE | PROTEIN COMPLEXES | MECHANISMS | INHIBITORS | IDENTIFICATION | GENOME | STREPTOMYCIN | Genes, Essential - drug effects | Bacteria - metabolism | Humans | Bacteria - drug effects | Drug Discovery - trends | Drug Discovery - methods | Anti-Bacterial Agents - isolation & purification | Bacteria - genetics | Animals | Anti-Bacterial Agents - classification | Anti-Bacterial Agents - chemistry | Bacteria - cytology | Anti-Bacterial Agents - pharmacology | Drug Resistance, Bacterial - drug effects | Genes, Bacterial - drug effects | Prevention | Pharmaceutical research | Research | Drug resistance | Pathogens | Enzymes | Cell growth | Microorganisms | Bacterial infections | Antibiotics | Metabolites | Bacteria | Antimicrobial agents | Mutation
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7. Gene mapping, discovery, and expression
: methods and protocols
by Bina, Minou
2006, Methods in Molecular Biology, ISBN 1588295753, Volume 338, xii, 334
Data processing | Genetics | Technique | Methodology | Gene mapping | Gene expression | Life Sciences | Cell Biology
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8. Full Text Discovery in Droplets
by Price, Alexander K and Paegel, Brian M
Analytical Chemistry, ISSN 0003-2700, 01/2016, Volume 88, Issue 1, pp. 339 - 353
CHEMISTRY, ANALYTICAL | FLUORINATED PICKERING EMULSIONS | GENETIC-ANALYSIS | ENZYME-KINETICS | HIGH-THROUGHPUT | CELL-LYSATE ASSAYS | COMPARTMENTS | GENERATION | MUTATIONS | MASS-SPECTROMETRY | MICROFLUIDICS | Particle Size | Oils - chemistry | Humans | Enzymes - metabolism | Surface-Active Agents - analysis | Enzymes - analysis
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9. Full Text Discovering the false discovery rate
by Yoav Benjamini
Journal of the Royal Statistical Society. Series B (Statistical Methodology), ISSN 1369-7412, 9/2010, Volume 72, Issue 4, pp. 405 - 416
I describe the background for the paper 'Controlling the false discovery rate: a new and powerful approach to multiple comparisons' by Benjamini and Hochberg... 
Hypothesis testing | Error rates | Null hypothesis | Research papers | Threshing | Inference | Parting phrases | Estimators | Estimation methods | Research methods | Testimation | False coverage rate | Multiple comparisons | STATISTICAL-METHODS | GENES | STATISTICS & PROBABILITY | HYPOTHESES | Studies | Research methodology | Statistical analysis | Methodology | Summaries
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