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Nature Immunology, ISSN 1529-2908, 2013, Volume 14, Issue 11, pp. 1190 - 1198
Although intergenic long noncoding RNAs (lincRNAs) have been linked to gene regulation in various tissues, little is known about lincRNA transcriptomes in the... 
STEM-CELLS | INTERFERON | INTEGRATIVE ANNOTATION | GENE-EXPRESSION | POPULATIONS | IMMUNOLOGY | GENOME-WIDE IDENTIFICATION | TRANSCRIPTION FACTOR | SEQ | CUTTING EDGE | REVEALS | GATA3 Transcription Factor - genetics | GATA3 Transcription Factor - immunology | STAT4 Transcription Factor - metabolism | STAT6 Transcription Factor - genetics | T-Box Domain Proteins - immunology | Th2 Cells - immunology | Transcriptome - immunology | Genetic Loci | Th1 Cells - immunology | RNA, Long Noncoding - immunology | Th1 Cells - metabolism | Th17 Cells - metabolism | Precursor Cells, T-Lymphoid - metabolism | Precursor Cells, T-Lymphoid - cytology | Th17 Cells - cytology | Cell Differentiation | GATA3 Transcription Factor - metabolism | STAT4 Transcription Factor - immunology | Signal Transduction | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Molecular Sequence Annotation | Th2 Cells - cytology | RNA, Long Noncoding - genetics | STAT6 Transcription Factor - metabolism | STAT6 Transcription Factor - immunology | T-Box Domain Proteins - genetics | Th2 Cells - metabolism | T-Box Domain Proteins - metabolism | Animals | Protein Binding | Th17 Cells - immunology | STAT4 Transcription Factor - genetics | Mice | Th1 Cells - cytology | Precursor Cells, T-Lymphoid - immunology | Cell Movement | Physiological aspects | Genetic aspects | Research | Cell differentiation | Gene expression | T cells | Index Medicus | Cell migration
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 10/2010, Volume 207, Issue 11, pp. 2331 - 2341
Foxp3-expressing regulatory T (T reg) cells have been implicated in parasite-driven inhibition of host immunity during chronic infection. We addressed whether... 
B-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | TH2 RESPONSES | PROTECTIVE IMMUNITY | TRANSCRIPTION FACTOR FOXP3 | IN-VIVO | AIRWAY INFLAMMATION | NEMATODE INFECTION | POLYGYRUS INFECTION | IMMUNOLOGY | ORAL ANTIGEN | AUTOIMMUNE-DISEASE | Receptors, Transforming Growth Factor beta - genetics | Strongylida Infections - metabolism | Receptors, Transforming Growth Factor beta - immunology | Smad3 Protein - immunology | Nematospiroides dubius - metabolism | Th2 Cells - immunology | T-Lymphocytes, Regulatory - immunology | Th1 Cells - metabolism | Host-Parasite Interactions - genetics | Phosphorylation - genetics | Smad2 Protein - genetics | Dioxoles - pharmacology | Phosphorylation - immunology | Protein-Serine-Threonine Kinases - metabolism | Smad2 Protein - metabolism | Mice, Transgenic | Signal Transduction - genetics | Antigens, Helminth - immunology | Receptors, Transforming Growth Factor beta - antagonists & inhibitors | Signal Transduction - drug effects | Mice | Mice, Inbred BALB C | Chronic Disease | Forkhead Transcription Factors - immunology | T-Lymphocytes, Regulatory - metabolism | Antigens, Helminth - metabolism | Strongylida Infections - genetics | Smad3 Protein - metabolism | Th1 Cells - immunology | Nematospiroides dubius - immunology | Signal Transduction - immunology | Smad3 Protein - genetics | Strongylida Infections - immunology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Benzamides - pharmacology | Transforming Growth Factor beta - immunology | Forkhead Transcription Factors - biosynthesis | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Protein-Serine-Threonine Kinases - genetics | Host-Parasite Interactions - immunology | Forkhead Transcription Factors - genetics | Th2 Cells - metabolism | Gene Expression Regulation - drug effects | Host-Parasite Interactions - drug effects | Smad2 Protein - immunology | Animals | Transforming Growth Factor beta - genetics | Receptors, Transforming Growth Factor beta - metabolism | Protein-Serine-Threonine Kinases - immunology | Cell Proliferation - drug effects | Transforming Growth Factor beta - metabolism | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 11/2012, Volume 109, Issue 46, pp. E3186 - E3195
Although macrophages are widely recognized to have a profibrotic role in inflammation, we have used a highly tractable CCl 4 -induced model of reversible... 
Degradation | Kupffer cell | Proliferation | Collagen | Myofibroblast | Kupffer Cell | LUNG FIBROSIS | proliferation | myofibroblast | MULTIDISCIPLINARY SCIENCES | collagen | degradation | HEPATIC-FIBROSIS | RENAL FIBROSIS | IMMUNE-RESPONSES | APOPTOTIC CELLS | IN-VIVO | MONOCYTE SUBSETS | GENE-EXPRESSION | PULMONARY-FIBROSIS | T-CELLS | Liver Cirrhosis - immunology | Antigens, Ly - genetics | Matrix Metalloproteinase 9 - immunology | Matrix Metalloproteinase 12 - genetics | Insulin-Like Growth Factor I - genetics | Monocytes - immunology | MAP Kinase Signaling System - immunology | Liver Cirrhosis - chemically induced | Insulin-Like Growth Factor I - immunology | CD11b Antigen - genetics | MAP Kinase Signaling System - genetics | Matrix Metalloproteinase 9 - genetics | Monocytes - pathology | Liver Cirrhosis - genetics | Macrophages - immunology | CD11b Antigen - immunology | Macrophages - pathology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Matrix Metalloproteinase 12 - immunology | Mice, Transgenic | Carbon Tetrachloride - toxicity | Carbon Tetrachloride Poisoning - pathology | Gene Expression Regulation - drug effects | Animals | MAP Kinase Signaling System - drug effects | Antigens, Ly - immunology | Carbon Tetrachloride Poisoning - immunology | Liver Cirrhosis - pathology | Carbon Tetrachloride Poisoning - genetics | Mice | Proteins | Genotype & phenotype | Signal transduction | Liver diseases | Gene expression | Rodents | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2015, Volume 125, Issue 12, pp. 4334 - 4348
Cellular metabolism is increasingly recognized as a controller of immune cell fate and function. MicroRNA-33 (miR-33) regulates cellular lipid metabolism and... 
MEDICINE, RESEARCH & EXPERIMENTAL | KNOCK-OUT MICE | RETINOIC ACID | INTERFERON-GAMMA | FATTY-ACID OXIDATION | GENE-EXPRESSION | ENHANCES ATHEROSCLEROSIS | CHOLESTEROL HOMEOSTASIS | HYPERLIPIDEMIC MICE | DEFICIENT MICE | ALTERNATIVE ACTIVATION | Forkhead Transcription Factors - immunology | Plaque, Atherosclerotic - genetics | Atherosclerosis - genetics | Macrophages, Peritoneal - pathology | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | Glycolysis - genetics | AMP-Activated Protein Kinases - immunology | Plaque, Atherosclerotic - pathology | Atherosclerosis - pathology | Atherosclerosis - immunology | Gene Expression Regulation - immunology | Macrophages, Peritoneal - immunology | Aldehyde Dehydrogenase - genetics | Plaque, Atherosclerotic - immunology | Forkhead Transcription Factors - genetics | MicroRNAs - immunology | Mice, Knockout | Animals | Oxygen Consumption - genetics | Oxygen Consumption - immunology | Mice | MicroRNAs - genetics | Aldehyde Dehydrogenase - immunology | AMP-Activated Protein Kinases - genetics | Glycolysis - immunology | MicroRNA | Atherosclerosis | Cell metabolism | Development and progression | Genetic aspects | Properties | Macrophages | Disease | Cytokines | Homeostasis | Inflammation | Kinases | Cholesterol | Studies | Genotype & phenotype | Metabolites | Rodents | MicroRNAs | Metabolic disorders | Index Medicus | Abridged Index Medicus
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2010, Volume 11, Issue 2, pp. 141 - 147
Journal Article
Immunity, ISSN 1074-7613, 05/2015, Volume 42, Issue 5, pp. 916 - 928
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 498, Issue 7453, pp. 236 - 240
Recent molecular studies have shown that, even when derived from a seemingly homogenous population, individual cells can exhibit substantial differences in... 
LEVEL | MESSENGER-RNA-SEQ | PATHWAY | MULTIDISCIPLINARY SCIENCES | RNA sequencing | Phenotype | Cellular control mechanisms | Research | Gene expression | Observations | Testing | Proteins | Noise | Cell cycle | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2012, Volume 109, Issue 2, pp. 582 - 587
Journal Article
Immunity, ISSN 1074-7613, 10/2014, Volume 41, Issue 4, pp. 567 - 578
Programmed necrosis or necroptosis is an inflammatory form of cell death that critically requires the receptor-interacting protein kinase 3 (RIPK3). Here we... 
PROTECTS MICE | APOPTOSIS | ACTIVATION | NECROSIS | INFLAMMATION | IN-VIVO | KINASE | INDUCED COLITIS | RECEPTOR | IMMUNOLOGY | INTESTINAL EPITHELIAL-CELLS | Dextran Sulfate | Receptors, Interleukin - biosynthesis | Colitis - genetics | Dendritic Cells - immunology | Transcription Factor RelB - immunology | Caspase 1 - metabolism | Adoptive Transfer | NF-kappa B p50 Subunit - genetics | Enzyme Activation - immunology | Lipopolysaccharides | Necrosis - immunology | NF-kappa B p50 Subunit - immunology | RNA, Messenger - biosynthesis | Signal Transduction - immunology | Bone Marrow Cells - immunology | Interleukins - immunology | Female | Interleukin-1beta - biosynthesis | Interleukins - biosynthesis | Wound Healing - genetics | Colitis - immunology | Macrophages - immunology | Transcription Factor RelB - genetics | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Interleukin-1beta - immunology | Inflammation - immunology | Interleukin-23 - immunology | Mice, Knockout | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Apoptosis - immunology | Interleukin-23 - biosynthesis | Mice | Enzyme Activation - genetics | Dendritic Cells - transplantation | Dextran | Cytokines | Dendritic cells | Sulfates | Inflammatory bowel disease | Rodents | Life sciences | Histology | Kinases | Experiments | Apoptosis | Index Medicus
Journal Article