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Blood, ISSN 0006-4971, 06/2011, Volume 117, Issue 23, pp. 6287 - 6296
B-cell receptor (BCR) signaling is aberrantly activated in chronic lymphocytic leukemia (CLL). Bruton tyrosine kinase (BTK) is essential to BCR signaling and... 
B-CELLS | CLL | FLUDARABINE PLUS CYCLOPHOSPHAMIDE | APOPTOTIC CELL-DEATH | RITUXIMAB | SURVIVAL SIGNALS | LYMPHOMA | DRUG-RESISTANCE | INHIBITOR | HEMATOLOGY | EXPRESSION | T-Lymphocytes - enzymology | Apoptosis - drug effects | Humans | Tumor Necrosis Factor-alpha - genetics | Cell Survival - genetics | Apoptosis - genetics | Male | NF-kappa B - metabolism | Neoplasm Proteins - antagonists & inhibitors | Receptors, Antigen, B-Cell - metabolism | Mitogen-Activated Protein Kinase 1 - genetics | Neoplasm Proteins - genetics | Interleukin-6 - metabolism | Cell Survival - drug effects | Drug Screening Assays, Antitumor - methods | Interleukin-6 - genetics | Mitogen-Activated Protein Kinase 3 - genetics | Gene Expression Regulation, Leukemic - drug effects | Pyrimidines - pharmacology | Leukemia, Lymphocytic, Chronic, B-Cell - enzymology | B-Cell Activating Factor - metabolism | CD40 Ligand - genetics | Mitogen-Activated Protein Kinase 3 - metabolism | Gene Expression Regulation, Enzymologic - genetics | Cell Line, Tumor | Receptors, Antigen, B-Cell - genetics | Mice | Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy | Mitogen-Activated Protein Kinase 1 - metabolism | Protein-Tyrosine Kinases - antagonists & inhibitors | Tumor Necrosis Factor-alpha - metabolism | Gene Expression Regulation, Enzymologic - drug effects | Phosphatidylinositol 3-Kinases - metabolism | Gene Expression Regulation, Leukemic - genetics | Protein-Tyrosine Kinases - genetics | CD40 Ligand - metabolism | MAP Kinase Signaling System - genetics | Female | Interleukin-4 - genetics | Protein-Tyrosine Kinases - biosynthesis | Pyrazoles - pharmacology | B-Lymphocytes - enzymology | Neoplasm Proteins - biosynthesis | Interleukin-4 - metabolism | Phosphatidylinositol 3-Kinases - genetics | Animals | MAP Kinase Signaling System - drug effects | NF-kappa B - genetics | B-Cell Activating Factor - genetics | Cell Proliferation - drug effects | Index Medicus | Abridged Index Medicus | Lymphoid Neoplasia
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2014, Volume 111, Issue 25, pp. 9157 - 9162
The transcription factor c-MYC is stabilized and activated by phosphorylation at serine 62 (S62) in breast cancer. Protein phosphatase 2A (PP2A) is a critical... 
Tumor cell line | Cell growth | Cell lines | Small interfering RNA | Breast cancer | Breast neoplasms | Heterologous transplantation | Tumors | Cancer | Apoptosis | Breast cancer therapy | Phosphatase activator | TUMOR-SUPPRESSOR PP2A | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | PROTEIN PHOSPHATASE 2A | CIP2A | OVEREXPRESSION | phosphatase activator | CELL-TRANSFORMATION | GENE | breast cancer therapy | MYELOID-LEUKEMIA | DEGRADATION | SUBUNIT | Gene Expression Regulation, Enzymologic - drug effects | Autoantigens - biosynthesis | Histone Chaperones - genetics | Humans | Autoantigens - genetics | Breast Neoplasms - metabolism | Drug Delivery Systems | Gene Knockdown Techniques | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - genetics | Protein Phosphatase 2 - antagonists & inhibitors | Membrane Proteins - genetics | Enzyme Inhibitors - pharmacology | Protein Phosphatase 2 - genetics | Transcription Factors - biosynthesis | Transcription Factors - genetics | Breast Neoplasms - drug therapy | Proto-Oncogene Proteins c-myc - metabolism | Membrane Proteins - biosynthesis | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Gene Expression Regulation, Enzymologic - genetics | Histone Chaperones - biosynthesis | Protein Phosphatase 2 - metabolism | Cell Line, Tumor | Proto-Oncogene Proteins c-myc - genetics | Physiological aspects | Tumor suppressor genes | Care and treatment | Transcription factors | Genetic aspects | Phosphorylation | Gene expression | Cells | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 03/2015, Volume 112, Issue 9, pp. 2841 - 2846
Journal Article
Neuron, ISSN 0896-6273, 04/2013, Volume 78, Issue 1, pp. 94 - 108
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2009, Volume 106, Issue 20, pp. 8380 - 8385
Journal Article
The Plant Cell, ISSN 1040-4651, 12/2002, Volume 14, Issue 12, pp. 3089 - 3099
During drought, the plant hormone abscisic acid (ABA) triggers stomatal closure, thus reducing water loss. Using infrared thermography, we isolated two allelic... 
Proteins | Phosphatases | Complementary DNA | Protoplasts | Guard cells | Stomata | Plants | Drought | Genetic mutation | Plant cells | ABA | PHOSPHATASE 2C | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLANT SCIENCES | CELL BIOLOGY | SIGNAL-TRANSDUCTION | THALIANA | ABI1 | GUARD-CELLS | HYDROGEN-PEROXIDE | ANION CHANNELS | ION CHANNELS | EXPRESSION | Plant Epidermis - physiology | Protein Kinases - metabolism | Amino Acid Sequence | Arabidopsis Proteins - genetics | Protein Kinases - genetics | Arabidopsis - enzymology | Reactive Oxygen Species - metabolism | Gene Expression Regulation, Plant - genetics | Molecular Sequence Data | Chromosome Mapping | Gene Expression Regulation, Enzymologic - physiology | Phylogeny | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Abscisic Acid - pharmacology | Disasters | Gene Expression Regulation, Enzymologic - genetics | Gene Expression Regulation, Plant - physiology | Cloning, Molecular | Plant Epidermis - cytology | Biological Transport - genetics | Biological Transport - physiology | Mutation | Water - physiology | Abscisic acid | Chemical properties | Research | Arabidopsis | Protein kinases | Index Medicus | Water | Reactive Oxygen Species | Abscisic Acid | Gene Expression Regulation, Enzymologic | Life Sciences | Natural Disasters | Arabidopsis Proteins | Protein Kinases | Biological Transport | Plant Epidermis | Gene Expression Regulation, Plant | Vegetal Biology
Journal Article
Neuron, ISSN 0896-6273, 2007, Volume 56, Issue 3, pp. 517 - 529
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2013, Volume 110, Issue 21, pp. 8644 - 8649
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2012, Volume 287, Issue 13, pp. 9817 - 9826
Journal Article