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Molecular cell, ISSN 1097-2765, 2017, Volume 67, Issue 4, pp. 608 - 621.e6
Transcription is a source of genetic instability that can notably result from the formation of genotoxic DNA:RNA hybrids, or R-loops, between the nascent mRNA... 
genetic instability | intron | recombination | mRNA splicing | transcription | mRNP | R-loops | messenger ribonucleoparticle | ELONGATION IMPAIRMENT | YEAST | MESSENGER-RNA | CANDIDA-GLABRATA | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLOBAL ANALYSIS | R-LOOP FORMATION | SACCHAROMYCES-CEREVISIAE | EXPRESSION | SCHIZOSACCHAROMYCES-POMBE | REVEALS | CELL BIOLOGY | Genomic Instability | Nucleic Acid Heteroduplexes - genetics | DNA, Fungal - genetics | Spliceosomes - genetics | Saccharomyces cerevisiae - genetics | Humans | Cryptococcus neoformans - genetics | Databases, Genetic | DNA, Fungal - chemistry | Structure-Activity Relationship | Nucleic Acid Heteroduplexes - metabolism | Saccharomyces cerevisiae - metabolism | Schizosaccharomyces - genetics | Spliceosomes - metabolism | RNA Splicing | Ribonucleoproteins - genetics | Transcription, Genetic | RNA, Fungal - genetics | Nucleic Acid Conformation | Gene Expression Regulation, Fungal | Cell Line | Introns | RNA, Fungal - chemistry | Computational Biology | Genotype | Ribonucleoproteins - metabolism | Fungal Proteins - genetics | Candida glabrata - metabolism | Cryptococcus neoformans - metabolism | Nucleic Acid Heteroduplexes - chemistry | RNA, Fungal - metabolism | Schizosaccharomyces - metabolism | Phenotype | DNA, Fungal - metabolism | DNA Damage | Candida glabrata - genetics | Fungal Proteins - metabolism | RNA | Analysis | Genes | Genomics | Genetic research | Genetic aspects | Genetic transcription | Anopheles | Messenger RNA | Cryptococcus neoformans | Life Sciences | RNA, Fungal | Spliceosomes | Schizosaccharomyces | Biochemistry, Molecular Biology | Ribonucleoproteins | Fungal Proteins | Candida glabrata | DNA, Fungal | Nucleic Acid Heteroduplexes | Molecular biology | Saccharomyces cerevisiae
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