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Oncogene, ISSN 0950-9232, 03/2013, Volume 32, Issue 13, pp. 1616 - 1625
HOTAIR is a long intervening non-coding RNA (lincRNA) that associates with the Polycomb Repressive Complex 2 (PRC2) and overexpression is correlated with poor... 
HOTAIR | Cell cycle progression | Pro-oncogenic | Invasion | Prognostic | ACTIVATION | pro-oncogenic | PROTEIN | CHROMATIN | DUCTAL ADENOCARCINOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | CELL BIOLOGY | prognostic | INTERFERON | invasion | LONG NONCODING RNA | REPRESSION | ONCOLOGY | GENETICS & HEREDITY | GENE-EXPRESSION | cell cycle progression | MIRNAS | Prognosis | Pancreatic Neoplasms - diagnosis | Humans | Transplantation, Heterologous | RNA, Long Noncoding - physiology | Carcinoma, Pancreatic Ductal - genetics | Gene Knockdown Techniques | Cell Transformation, Neoplastic - genetics | Biomarkers, Tumor - metabolism | Carcinoma, Pancreatic Ductal - diagnosis | Female | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - physiology | Pancreatic Neoplasms - pathology | RNA, Small Interfering - pharmacology | Pancreatic Neoplasms - genetics | Biomarkers, Tumor - physiology | RNA, Long Noncoding - genetics | Carcinoma, Pancreatic Ductal - pathology | Animals | Cell Line, Tumor | Biomarkers, Tumor - genetics | Cell Proliferation - drug effects | Mice | Cell Transformation, Neoplastic - drug effects | RNA, Long Noncoding - antagonists & inhibitors | RNA, Long Noncoding - metabolism | RNA | Pancreatic cancer | Physiological aspects | Genetic aspects | Research | Gene expression | Oncology | Cell cycle | Tumors | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2011, Volume 108, Issue 40, pp. 16669 - 16674
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, pp. e84256 - e84256
Journal Article
The Journal of Pathology, ISSN 0022-3417, 11/2012, Volume 228, Issue 3, pp. 391 - 404
Aldehyde dehydrogenase 1 (ALDH1) has been shown to serve as a marker for cancer‐initiating cells (CICs), but little is known about the regulation of the CIC... 
cancer‐initiating cells | TGF‐β | ALDH1 | diffuse‐type gastric cancer | REG4 | cancer-initiating cells | diffuse-type gastric cancer | TGF-β | NUDE-MICE | STEM-CELLS | METASTATIC MODEL | PROTEIN | MARKER | PATHOLOGY | ESTABLISHMENT | IV | BREAST-CANCER CELLS | GROWTH-FACTOR-BETA | ONCOLOGY | PROSTATE-CANCER | TGF-ss | Adenocarcinoma - pathology | Humans | Lectins, C-Type - physiology | Stomach Neoplasms - pathology | Transplantation, Heterologous | Retinal Dehydrogenase - physiology | Stomach Neoplasms - physiopathology | Carcinoma, Signet Ring Cell - physiopathology | Adenocarcinoma - physiopathology | Up-Regulation - physiology | Neoplastic Stem Cells - pathology | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - physiology | Neoplastic Stem Cells - physiology | Disease Models, Animal | Isoenzymes - physiology | Carcinoma, Signet Ring Cell - pathology | Cells, Cultured | Transforming Growth Factor beta - physiology | Biomarkers, Tumor - physiology | Down-Regulation - drug effects | Pancreatitis-Associated Proteins | Transforming Growth Factor beta - pharmacology | Animals | Mice, Nude | Cell Line, Tumor | Signal Transduction - physiology | Mice | Mice, Inbred BALB C | Cell Transformation, Neoplastic - pathology | Immunohistochemistry | Phosphorylation | Dehydrogenases | Population number | Smad3 protein | Gene expression | Aldehydes | Dehydrogenase | Aldehyde dehydrogenase | Signaling | DNA microarrays | Cell size | Inhibition | Islets of Langerhans | Pancreas | Gastric cancer | Cancer | Tumors | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 19, Issue 1, pp. 58 - 71
Activation of the PI3K-AKT pathway in tumors is modulated by negative feedback, including mTORC1-mediated inhibition of upstream signaling. We now show that... 
RAPAMYCIN | TARGET | FORKHEAD TRANSCRIPTION FACTOR | CELLS | INSULIN-RECEPTOR | ACTIVATION | ONCOLOGY | SIGNALING PATHWAY | PHOSPHORYLATION | UPSTREAM | HUMAN CANCER | CELL BIOLOGY | RNA, Small Interfering - genetics | Receptor, IGF Type 1 - metabolism | Protein Binding - genetics | Receptor, ErbB-3 - metabolism | Humans | Forkhead Transcription Factors - metabolism | Protein Binding - drug effects | Receptor Protein-Tyrosine Kinases - antagonists & inhibitors | Receptor, ErbB-2 - antagonists & inhibitors | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Quinoxalines - therapeutic use | Carcinoma, Non-Small-Cell Lung - metabolism | Receptor, ErbB-3 - genetics | Receptor Protein-Tyrosine Kinases - metabolism | Breast Neoplasms - drug therapy | Receptor, IGF Type 1 - genetics | Signal Transduction - drug effects | Mice, Nude | Models, Biological | Cell Line, Tumor | Mice | TOR Serine-Threonine Kinases | Feedback, Physiological - physiology | Quinazolines - pharmacology | Proteins - antagonists & inhibitors | Neoplasms - metabolism | Gene Expression - drug effects | Multiprotein Complexes | Receptor, ErbB-2 - metabolism | Promoter Regions, Genetic - genetics | Proto-Oncogene Proteins c-akt - genetics | Breast Neoplasms - metabolism | Mechanistic Target of Rapamycin Complex 1 | Quinoxalines - pharmacology | Receptor, Insulin - genetics | Female | Forkhead Transcription Factors - antagonists & inhibitors | Gene Expression Regulation, Neoplastic - drug effects | Drug Therapy, Combination | Gene Expression Regulation, Neoplastic - physiology | Carcinoma, Non-Small-Cell Lung - pathology | Up-Regulation - genetics | Forkhead Transcription Factors - genetics | Xenograft Model Antitumor Assays | Animals | Receptor Protein-Tyrosine Kinases - genetics | Breast Neoplasms - pathology | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Feedback, Physiological - drug effects | Receptor, Insulin - metabolism | Signal Transduction - physiology | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Benzylamines - pharmacology | Benzylamines - therapeutic use | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Index Medicus
Journal Article
Nature Genetics, ISSN 1061-4036, 07/2013, Volume 45, Issue 7, pp. 739 - 746
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 11/2003, Volume 163, Issue 4, pp. 847 - 857
Journal Article
Journal Article