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1. Full Text Gene knockout protocols
by Kühn, Ralf and Wurst, Wolfgang, 1955
2009, 2nd ed., Springer protocols, ISBN 9781934115268, Volume 530.
Gene targeting | Gene Knockout Techniques | methods | Transgenic mice
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2. Full Text Pituitary Gonadotrophic Hormone Synthesis, Secretion, Subunit Gene Expression and Cell Structure in Normal and Follicle‐Stimulating Hormone β Knockout, Follicle‐Stimulating Hormone Receptor Knockout, Luteinising Hormone Receptor Knockout, Hypogonadal and Ovariectomised Female Mice
by Abel, M. H and Widen, A and Wang, X and Huhtaniemi, I and Pakarinen, P and Kumar, T. R and Christian, H. C
Journal of Neuroendocrinology, ISSN 0953-8194, 11/2014, Volume 26, Issue 11, pp. 785 - 795
To investigate the relationship between gonadotroph function and ultrastructure, we have compared, in parallel in female mice, the effects of several different... 
luteinising hormone | anterior pituitary | ultrastructure | gonadotrophs | follicle‐stimulating hormone | follicle-stimulating hormone | ANTERIOR-PITUITARY | CHROMOGRANIN-A | SECRETOGRANIN-II | NEUROSCIENCES | RAT ESTROUS-CYCLE | HPG MOUSE | TARGETED DISRUPTION | MESSENGER-RNA | ENDOCRINOLOGY & METABOLISM | GONADAL-FUNCTION | TRANSGENIC MICE | Follicle Stimulating Hormone - metabolism | Gene Expression | Luteinizing Hormone - genetics | Pituitary Gland - metabolism | RNA, Messenger - genetics | Luteinizing Hormone - metabolism | RNA, Messenger - metabolism | Protein Subunits - metabolism | Mice, Knockout | Hypogonadism - genetics | Animals | Hypogonadism - metabolism | Female | Mice | Pituitary Gland - cytology | Follicle Stimulating Hormone - genetics | Protein Subunits - genetics
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3. Full Text The gene knockout factsbook
by Mak, Tak W., 1945
1998, Factsbook series, ISBN 9780124660465, 1088
The FactsBooks Series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as "a growing series of... 
Proteins | Genetics | Mice | Handbooks, manuals, etc | Genes | Gene targeting | Transgenic mice
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4. Full Text Searching for cognitive enhancement in the Morris water maze: better and worse performance in D‐amino acid oxidase knockout (Dao−/−) mice
by Pritchett, David and Taylor, Amy M and Barkus, Christopher and Engle, Sandra J and Brandon, Nicholas J and Sharp, Trevor and Foster, Russell G and Harrison, Paul J and Peirson, Stuart N and Bannerman, David M and Isles, Anthony
European Journal of Neuroscience, ISSN 0953-816X, 04/2016, Volume 43, Issue 7, pp. 979 - 989
A common strategy when searching for cognitive‐enhancing drugs has been to target the N‐methyl‐d‐aspartate receptor (NMDAR), given its putative role in... 
D‐serine | pre‐clinical model | N‐methyl‐d‐aspartate receptor | schizophrenia | glutamate | N-methyl-D-aspartate receptor | Schizophrenia | Pre-clinical model | D-serine | Glutamate | METABOTROPIC GLUTAMATE RECEPTORS | SYNAPTIC PLASTICITY | NEUROSCIENCES | NMDA-RECEPTOR | DOUBLE-BLIND | SPATIAL MEMORY | LONG-TERM POTENTIATION | SEX-DIFFERENCES | INHIBITOR | pre-clinical model | Animals | Maze Learning | Memory, Long-Term | D-Amino-Acid Oxidase - genetics | Female | Male | Cognition | Mice | Spatial Memory | D-Amino-Acid Oxidase - metabolism | Oxidases | Animal experimentation | Methyl aspartate | Gene mutations | Analysis | Glycine | Cognitive Neuroscience | Research Report
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5. Cytokine knockouts
by Fantuzzi, Giamila
2003, 2nd ed., Contemporary immunology, ISBN 1588291944, xix, 471
Cytokines | Gene targeting
Book
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6. Gene knockout protocols
by Tymms, Martin J and Kola, Ismail and SpringerLink (Online service)
2001, Methods in molecular biology, ISBN 9780896035720, Volume 158., xi, 431
As the major task of sequencing the human genome nears completion and the full complement of human genes are catalogued, the task of understanding the normal... 
Gene targeting | Transgenic mice | Laboratory manuals | Human genetics | Human Genetics | Biomedicine
Book
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7. Full Text Enhanced long-term potentiation and impaired learning in phosphodiesterase 4D-knockout (PDE4D(-/-)) mice
by Rutten, K and Misner, D.L and Works, M and Blokland, A and Novak, T.J and Santarelli, L and Wallace, T
European Journal of Neuroscience, ISSN 0953-816X, 01/2008, Volume 28, Issue 3, pp. 625 - 632
Elevation of intracellular cyclic adenosine monophosphate (cAMP) concentrations and subsequent regulation of downstream target gene expression through... 
gene knockout | mouse | LTP | fear conditioning | cAMP | PDE4 | Mouse | Gene knockout | Fear conditioning | REQUIRES PROTEIN-SYNTHESIS | HIPPOCAMPAL CA1 NEURONS | DEPENDENT MEMORY | SYNAPTIC PLASTICITY | NEUROSCIENCES | ROLIPRAM | MEMORY CONSOLIDATION | MOUSE MODEL | REDUCED SENSITIVITY | PDE4B ENZYME | Motor Activity - physiology | Synaptic Transmission - physiology | Isoenzymes - genetics | Mice, Inbred C57BL | Electrophysiology | Behavior, Animal - physiology | Cyclic Nucleotide Phosphodiesterases, Type 4 - genetics | Fear - physiology | Conditioning, Classical - physiology | Mice, Knockout | Learning - physiology | Animals | Neuronal Plasticity - physiology | Isoenzymes - metabolism | Long-Term Potentiation - physiology | Mice | Cyclic Nucleotide Phosphodiesterases, Type 4 - metabolism | Memory - physiology | Esterases
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8. Full Text The Knockout Mouse Project
by Austin, Christopher P and Battey, James F and Bradley, Allan and Bucan, Maja and Capecchi, Mario and Collins, Francis S and Dove, William F and Duyk, Geoffrey and Dymecki, Susan and Eppig, Janan T and Grieder, Franziska B and Heintz, Nathaniel and Hicks, Geoff and Insel, Thomas R and Joyner, Alexandra and Koller, Beverly H and Lloyd, K. C. Kent and Magnuson, Terry and Moore, Mark W and Nagy, Andras and Pollock, Jonathan D and Roses, Allen D and Sands, Arthur T and Seed, Brian and Skarnes, William C and Snoddy, Jay and Soriano, Philippe and Stewart, David J and Stewart, Francis and Stillman, Bruce and Varmus, Harold and Varticovski, Lyuba and Verma, Inder M and Vogt, Thomas F and Von Melchner, Harald and Witkowski, Jan and Woychik, Richard P and Wurst, Wolfgang and Yancopoulos, George D and Young, Stephen G and Zambrowicz, Brian and Comprehensive Knockout Mouse Proje and The Comprehensive Knockout Mouse Project Consortium
Nature Genetics, ISSN 1061-4036, 09/2004, Volume 36, Issue 9, pp. 921 - 924
Mouse knockout technology provides a powerful means of elucidating gene function in vivo, and a publicly available genome-wide collection of mouse knockouts... 
EMBRYONIC STEM-CELLS | SEQUENCE | GENETICS & HEREDITY | GENE-TRAP MUTAGENESIS | PHENOTYPE | MICE | IDENTIFICATION | GENOME | DEFICIENCY | INSIGHTS | RESOURCE | Research Embryo Creation - economics | Phenotype | Animals | Genetic Research | Alleles | Mice | Mice, Knockout | Usage | Gene mutations | Physiological aspects | Genetic aspects | Nucleotide sequencing | Research | Identification and classification | Methods
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9. Cytokine knockouts
by Durum, Scott K and Muegge, Kathrin
1998, Contemporary immunology., ISBN 9780896033689, xxv, 482
Cytokines | Gene targeting
Book
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10. Full Text Activation of aldehyde dehydrogenase 2 (ALDH2) confers cardioprotection in protein kinase C epsilon (PKCɛ) knockout mice
by Budas, Grant R and Disatnik, Marie-Hélène and Chen, Che-Hong and Mochly-Rosen, Daria
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2009, Volume 48, Issue 4, pp. 757 - 764
Abstract Acute administration of ethanol can reduce cardiac ischemia/reperfusion injury. Previous studies demonstrated that the acute cytoprotective effect of... 
Cardiovascular | Aldehyde dehydrogenase 2 | Cardiac ischemia | Signaling | Protein kinase C | Preconditioning | CARDIAC & CARDIOVASCULAR SYSTEMS | STIMULATION | LIPID-PEROXIDATION | ISCHEMIA | CELL BIOLOGY | OVEREXPRESSION | ALCOHOL | SIGNALING PATHWAY | 4-HYDROXYNONENAL-INDUCED APOPTOSIS | ACUTE ETHANOL | STRESS | RABBIT HEARTS | Signal Transduction | Reperfusion Injury | Aldehyde Dehydrogenase, Mitochondrial | Heart - physiology | Humans | Protein Kinase C-epsilon - genetics | Mice, Knockout | Myocardial Ischemia - pathology | Gene Expression Regulation, Enzymologic | Animals | Ethanol - chemistry | Protein Kinase C - metabolism | Protein Kinase C-epsilon - metabolism | Mice | Enzyme Activation | Mutation | Aldehyde Dehydrogenase - metabolism | Aldehydes | Protein kinases
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11. Full Text Efficient TALEN-mediated gene knockout in livestock
by Daniel F. Carlson and Wenfang Tan and Simon G. Lillico and Dana Stverakova and Chris Proudfoot and Michelle Christian and Daniel F. Voytas and Charles R. Long and C. Bruce A. Whitelaw and Scott C. Fahrenkrug
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2012, Volume 109, Issue 43, pp. 17382 - 17387
Transcription activator-like effector nucleases (TALENs) are programmable nucleases that join Fokl endonuclease with the modular DNA-binding domain of TALEs.... 
Transposons | Messenger RNA | Transfection | Alleles | Fibroblasts | Livestock | Genomes | Genetic engineering | Embryos | Scaffolds | Biotechnology | Tal-effector nuclease | Gene-editing | PIGS | biotechnology | FAMILIAL HYPERCHOLESTEROLEMIA | MULTIDISCIPLINARY SCIENCES | BEAUTY TRANSPOSON SYSTEM | ZINC-FINGER NUCLEASES | MAMMALIAN-CELLS | FIBROBLASTS | gene-editing | HUMAN GENOME | DISRUPTION | GENERATION | EXPRESSION | Chromosome Deletion | Cloning, Organism | Molecular Sequence Data | Transcription Factors - genetics | Gene Knockout Techniques | Livestock - genetics | Chromosome Inversion | Sequence Homology, Nucleic Acid | DNA Transposable Elements | Animals | Cattle | Swine | Base Sequence | DNA | Animal genetics | Poultry | Physiological aspects | Genetic aspects | Genetic transcription | Research | Gene expression | Biological Sciences
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12. Full Text Endothelium-Dependent Contractions Occur in the Aorta of Wild-Type and COX2−/− Knockout But Not COX1−/− Knockout Mice
by Tang, Eva H. C and Ku, David D and Tipoe, George L and Feletou, Michel and Man, Ricky Y. K and Vanhoutte, Paul M
Journal of Cardiovascular Pharmacology, ISSN 0160-2446, 12/2005, Volume 46, Issue 6, pp. 761 - 765
The present experiments were designed to determine whether or not endothelium-dependent contractions can be evoked in the aorta of the mouse, and if so,... 
Aorta | Cyclooxygenase | Mice | Endothelium-dependent contractions | Endothelium-derived contracting factors | GENDER-DIFFERENCE | CARDIAC & CARDIOVASCULAR SYSTEMS | SPONTANEOUSLY HYPERTENSIVE-RATS | ACETYLCHOLINE | MOUSE | cyclooxygenase | ARACHIDONIC-ACID | mice | endothelium-derived contracting factors | FREE-RADICALS | NITRIC-OXIDE | GENE DISRUPTION | PHARMACOLOGY & PHARMACY | aorta | DYSFUNCTION | SHR | endothelium-dependent contractions | NG-Nitroarginine Methyl Ester - pharmacology | Endothelins - physiology | Mice, Inbred C57BL | Vasoconstriction | Cyclooxygenase 1 - physiology | Cyclooxygenase 2 - physiology | Male | Sex Characteristics | Calcimycin - pharmacology | Endothelium, Vascular - physiology | Mice, Knockout | Animals | Female | In Vitro Techniques | Aorta - physiology
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13. Full Text d‐amino acid oxidase knockout (Dao−/−) mice show enhanced short‐term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption
by Pritchett, David and Hasan, Sibah and Tam, Shu K. E and Engle, Sandra J and Brandon, Nicholas J and Sharp, Trevor and Foster, Russell G and Harrison, Paul J and Bannerman, David M and Peirson, Stuart N
European Journal of Neuroscience, ISSN 0953-816X, 05/2015, Volume 41, Issue 9, pp. 1167 - 1179
d‐amino acid oxidase (DAO, DAAO) is an enzyme that degrades d‐serine, the primary endogenous co‐agonist of the synaptic N‐methyl‐d‐aspartate receptor.... 
N‐methyl‐d‐aspartate receptor | preclinical model | schizophrenia | glutamate | d‐serine | Schizophrenia | Glutamate | N-methyl-d-aspartate receptor | d-serine | Preclinical model | CEREBROSPINAL-FLUID | NEUROSCIENCES | MOUSE MODELS | NMDA-RECEPTOR | MUTANT MICE | DOUBLE-BLIND | RAT-BRAIN | RECEPTOR GLYCINE AFFINITY | COGNITIVE DEFICITS | WORKING-MEMORY | Avoidance Learning | Anxiety - physiopathology | D-Amino-Acid Oxidase - genetics | Male | Circadian Rhythm | Animals | Maze Learning | Sleep | Gene Deletion | Female | Mice | D-Amino-Acid Oxidase - metabolism | Memory, Short-Term | Anxiety - metabolism | Oxidases | Methyl aspartate | Analysis | Memory | Genetically modified organisms | Aspartate | Genetic engineering | Anxiety | Behavioral Neuroscience
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