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1. Full Text A conditional knockout resource for the genome-wide study of mouse gene function
by Skarnes, William C and Rosen, Barry and West, Anthony P and Koutsourakis, Manousos and Bushell, Wendy and Iyer, Vivek and Mujica, Alejandro O and Thomas, Mark and Harrow, Jennifer and Cox, Tony and Jackson, David and Severin, Jessica and Biggs, Patrick and Fu, Jun and Nefedov, Michael and De Jong, Pieter J and Stewart, A. Francis and Bradley, Allan
Nature (London), ISSN 0028-0836, 06/2011, Volume 474, Issue 7351, pp. 337 - 344
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Classical genetics, quantitative genetics, hybrids | Biological and medical sciences | Vertebrata | Animals | Genetics of eukaryotes. Biological and molecular evolution | Mice, Knockout - genetics | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Mutagenesis, Insertional - methods | Genomics | Humans | Mice, Inbred C57BL | Computational Biology | Genome - genetics | Genes - genetics | Genetic Association Studies - methods | Rats | Genotype | Gene Knockout Techniques - methods | Genetic Vectors - genetics | Phenotype | Gene Deletion | Genes, Lethal - genetics | Alleles | Polymerase Chain Reaction | Mice | Proteins | Genetics | Mutation | Genes | Index Medicus
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2. Full Text Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening
by Joung, Julia and Konermann, Silvana and Gootenberg, Jonathan S and Abudayyeh, Omar O and Platt, Randall J and Brigham, Mark D and Sanjana, Neville E and Zhang, Feng
Nature protocols, ISSN 1754-2189, 04/2017, Volume 12, Issue 4, pp. 828 - 863
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Phenotype | Animals | Gene Library | Humans | Transcriptional Activation | Lentivirus - genetics | Mice | Genomics - methods | CRISPR-Cas Systems - genetics | Gene Knockout Techniques - methods | Genetic Vectors - genetics | Genetic engineering | Models | Genetic transcription | Analysis | Innovations | Index Medicus
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3. Full Text Gene knockout protocols
by Kühn, Ralf and Wurst, Wolfgang, 1955
2009, 2nd ed., Springer protocols, ISBN 9781934115268, Volume 530.
Gene targeting | Gene Knockout Techniques | methods | Transgenic mice
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4. Full Text Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
by Ophir Shalem and Neville E. Sanjana and Ella Hartenian and Xi Shi and David A. Scott and Tarjei S. Mikkelsen and Dirk Heckl and Benjamin L. Ebert and David E. Root and John G. Doench and Feng Zhang
Science (American Association for the Advancement of Science), ISSN 0036-8075, 1/2014, Volume 343, Issue 6166, pp. 84 - 87
T lymphocytes | HEK293 cells | Genetic vectors | Genomics | REPORTS | Cell lines | Stem cells | Melanoma | Genetic loci | Genetic mutation | Genetic screening | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Genome-Wide Association Study | Gene Library | raf Kinases - antagonists & inhibitors | Humans | Selection, Genetic | Cell Survival - genetics | Mediator Complex - genetics | Genetic Loci | Transcription Factors - genetics | Gene Knockout Techniques | Genes, Neurofibromatosis 1 | Genes, Neurofibromatosis 2 | Genetic Testing - methods | Lentivirus | Cullin Proteins - genetics | Pluripotent Stem Cells - metabolism | Drug Resistance, Neoplasm - genetics | Sulfonamides - therapeutic use | Melanoma - genetics | Protein Kinase Inhibitors - therapeutic use | Melanoma - drug therapy | Adaptor Proteins, Signal Transducing - genetics | Clustered Regularly Interspaced Short Palindromic Repeats | Indoles - therapeutic use | RNA sequencing | Genome-wide association studies | Research | Studies | Genetic engineering | Pharmaceutical sciences | Index Medicus
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5. Full Text Easi-CRISPR for creating knock-in and conditional knockout mouse models using long ssDNA donors
by Miura, Hiromi and Quadros, Rolen M and Gurumurthy, Channabasavaiah B and Ohtsuka, Masato
Nature protocols, ISSN 1754-2189, 01/2018, Volume 13, Issue 1, pp. 195 - 215
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | DNA, Single-Stranded - genetics | Animals | Mice, Inbred C57BL | Female | Male | Gene Editing - methods | Mice | CRISPR-Cas Systems - genetics | Gene Knock-In Techniques - methods | Gene Knockout Techniques - methods | Mice, Knockout | Animal experimentation | Genetic research | Genetic engineering | Models | Research | Gene expression | Methods | CRISPR | Animal models | Efficiency | Exons | Rodents | Insertion | Inserts | Genomes | Deoxyribonucleic acid--DNA | Index Medicus
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6. Full Text Physiological roles of long noncoding RNAs: insight from knockout mice
by Li, Lingjie and Chang, Howard Y
Trends in cell biology, ISSN 0962-8924, 2014, Volume 24, Issue 10, pp. 594 - 602
Pathology | knockout | phenotype | gene targeting | lncRNA | genetic study | Phenotype | Genetic study | Gene targeting | Knockout | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Gene Targeting - methods | Animals | Humans | RNA, Long Noncoding - administration & dosage | Gene Targeting - trends | Mice | RNA, Long Noncoding - physiology | Gene Knockout Techniques - trends | Gene Knockout Techniques - methods | Mice, Knockout | Index Medicus
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7. Full Text CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes
by Evers, Bastiaan and Jastrzebski, Katarzyna and Heijmans, Jeroen P. M and Grernrum, Wipawadee and Beijersbergen, Roderick L and Bernards, Rene
Nature biotechnology, ISSN 1087-0156, 06/2016, Volume 34, Issue 6, pp. 631 - 633
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | RNA, Small Interfering - genetics | Gene Expression Profiling - methods | Clustered Regularly Interspaced Short Palindromic Repeats - genetics | Genetic Testing - methods | Genetic Markers - genetics | Gene Knockout Techniques - methods | Comparative analysis | Genetic screening | High-throughput screening (Biochemical assaying) | Oncology | Genetic testing | Ribonucleic acid--RNA | Research & development--R&D | Index Medicus
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8. Full Text Efficient CRISPR/Cas9-based gene knockout in watermelon
by Tian, Shouwei and Tian, Shouwei and Jiang, Linjian and Jiang, Linjian and Gao, Qiang and Gao, Qiang and Zhang, Jie and Zhang, Jie and Zong, Mei and Zong, Mei and Zhang, Haiying and Zhang, Haiying and Ren, Yi and Ren, Yi and Guo, Shaogui and Guo, Shaogui and Gong, Guoyi and Gong, Guoyi and Liu, Fan and Liu, Fan and Xu, Yong and Xu, Yong
Plant cell reports, ISSN 0721-7714, 3/2017, Volume 36, Issue 3, pp. 399 - 406
Life Sciences | Biotechnology | Plant Biochemistry | CRISPR/Cas9 | Watermelon | Genome editing | Plant Sciences | PDS | Cell Biology | Life Sciences & Biomedicine | Science & Technology | Citrullus - genetics | Gene Targeting | Protoplasts - metabolism | Base Sequence | Plants, Genetically Modified | Mutagenesis - genetics | Genetic Vectors - metabolism | Genome, Plant | CRISPR-Cas Systems - genetics | Plasmids - metabolism | Gene Editing | Gene Knockout Techniques - methods | Anopheles | Fruit | RNA | Genes | Genomics | Genetic research | Forests and forestry | Genetic engineering | Plants | Index Medicus
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9. Full Text A Rapid Method for Directed Gene Knockout for Screening in G0 Zebrafish
by Wu, Roland S and Lam, Ian I and Clay, Hilary and Duong, Daniel N and Deo, Rahul C and Coughlin, Shaun R
Developmental cell, ISSN 1534-5807, 07/2018, Volume 46, Issue 1, pp. 112 - 125.e4
CRISPR | zebrafish | Cas9 | gene editing | mutagenesis | reverse genetic screen | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Genetic Engineering - methods | Morpholinos - genetics | Myocytes, Cardiac - cytology | Heart - embryology | GTP-Binding Protein alpha Subunits, G12-G13 - genetics | Zebrafish - embryology | CRISPR-Cas Systems - genetics | Gene Knockout Techniques - methods | Zebrafish - genetics | Animals | Base Sequence | Promyelocytic Leukemia Zinc Finger Protein - genetics | Clustered Regularly Interspaced Short Palindromic Repeats - genetics | Transcription, Genetic - genetics | Zebrafish Proteins - genetics | Index Medicus
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