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Nature Medicine, ISSN 1078-8956, 01/2007, Volume 13, Issue 1, pp. 100 - 106
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2010, Volume 107, Issue 13, pp. 5810 - 5814
Journal Article
eLife, ISSN 2050-084X, 2014, Volume 3, p. e04120
The HIV-1 protein Rev controls a critical step in viral replication by mediating the nuclear export of unspliced and singly-spliced viral mRNAs. Multiple Rev... 
viruses | HIV | infectious disease | nuclear export | biochemistry | protein-RNA structure | microbiology | rev Gene Products, Human Immunodeficiency Virus - chemistry | Virus Replication - genetics | Humans | Crystallography, X-Ray | rev Gene Products, Human Immunodeficiency Virus - metabolism | T-Lymphocytes - virology | RNA Splicing | Cell Nucleus - metabolism | RNA, Viral - genetics | T-Lymphocytes - metabolism | Cell Nucleus - virology | Escherichia coli - metabolism | HEK293 Cells | RNA, Viral - metabolism | Active Transport, Cell Nucleus | Binding Sites | Recombinant Proteins - metabolism | HIV-1 - metabolism | Response Elements | Signal Transduction | Gene Expression Regulation | Models, Molecular | Receptors, Cytoplasmic and Nuclear - genetics | Recombinant Proteins - genetics | HIV-1 - genetics | Cytosol - virology | Host-Pathogen Interactions | Karyopherins - metabolism | RNA, Viral - chemistry | Escherichia coli - genetics | Cell Line, Tumor | Karyopherins - genetics | Protein Binding | Cytosol - metabolism | rev Gene Products, Human Immunodeficiency Virus - genetics | HeLa Cells | Receptors, Cytoplasmic and Nuclear - metabolism | Plasticity (functional) | Interfaces | Proteins | Oligomerization | Packing | Nucleotide sequence | Human immunodeficiency virus--HIV | Mutation | Hydrophobicity | Ribonucleic acid--RNA | Nuclear transport | Crystal structure
Journal Article
Journal Article
Cell, ISSN 0092-8674, 10/2013, Volume 155, Issue 3, pp. 594 - 605
Journal Article
Journal Article
Molecular Therapy, ISSN 1525-0016, 12/2011, Volume 19, Issue 12, pp. 2228 - 2238
We evaluated the in vivo efficacy of structurally flexible, cationic PAMAM dendrimers as a small interfering RNA (siRNA) delivery system in a Rag2‐/‐γc‐/‐... 
MEDICINE, RESEARCH & EXPERIMENTAL | DOUBLE-STRANDED-RNA | PAMAM DENDRIMERS | PRIMARY-CELLS | SIRNA DELIVERY | CLEAVAGE | POTENT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PROGRESS | DISEASE | GENETICS & HEREDITY | INTERFERENCE | THERAPIES | HIV Infections - prevention & control | Leukocytes, Mononuclear - metabolism | RNA, Small Interfering - genetics | Humans | rev Gene Products, Human Immunodeficiency Virus - metabolism | Leukocytes, Mononuclear - virology | Viral Load | T-Lymphocytes, Helper-Inducer - virology | CD4-Positive T-Lymphocytes - immunology | Dendrimers | Flow Cytometry | HIV-1 - physiology | RNA, Viral - genetics | T-Lymphocytes, Helper-Inducer - immunology | tat Gene Products, Human Immunodeficiency Virus - antagonists & inhibitors | CD4-Positive T-Lymphocytes - virology | DEAD-box RNA Helicases - metabolism | Interleukin Receptor Common gamma Subunit - physiology | Disease Models, Animal | DNA-Binding Proteins - physiology | Ribonuclease III - metabolism | tat Gene Products, Human Immunodeficiency Virus - genetics | HIV Infections - genetics | HIV Infections - virology | Liver - metabolism | Viremia - genetics | Mice, Knockout | Animals | Viremia - virology | Viremia - prevention & control | Leukocytes, Mononuclear - cytology | Liver - cytology | Mice | Mice, Inbred BALB C | Nanoparticles - administration & dosage | rev Gene Products, Human Immunodeficiency Virus - genetics | rev Gene Products, Human Immunodeficiency Virus - antagonists & inhibitors | RNA, Small Interfering - administration & dosage | tat Gene Products, Human Immunodeficiency Virus - metabolism | Original
Journal Article
Journal Article
PLoS Pathogens, ISSN 1553-7366, 07/2006, Volume 2, Issue 7, pp. 0650 - 0661
HIV-1 latency in resting CD4(+) T cells represents a major barrier to virus eradication in patients on highly active antiretroviral therapy ( HAART). We... 
MICROBIOLOGY | PARASITOLOGY | VIROLOGY | tat Gene Products, Human Immunodeficiency Virus | Gene Products, tat - genetics | HIV-1 - pathogenicity | Virus Replication - genetics | Humans | CD4-Positive T-Lymphocytes - physiology | Acquired Immunodeficiency Syndrome - genetics | Cell Nucleus - physiology | Virus Latency - physiology | Polypyrimidine Tract-Binding Protein - analysis | Lymphocyte Activation - genetics | RNA Splicing | HIV-1 - physiology | RNA, Viral - genetics | Cell Nucleus - virology | Polypyrimidine Tract-Binding Protein - physiology | CD4-Positive T-Lymphocytes - virology | CD4-Positive T-Lymphocytes - chemistry | Gene Products, rev - physiology | Gene Products, tat - physiology | RNA, Viral - analysis | Gene Products, rev - analysis | HIV-1 - genetics | Antiretroviral Therapy, Highly Active | Acquired Immunodeficiency Syndrome - physiopathology | Gene Products, rev - genetics | Gene Expression Regulation, Viral | rev Gene Products, Human Immunodeficiency Virus | Cell Nucleus - chemistry | Gene Products, tat - analysis | Lymphocyte Activation - physiology | Virus Replication - physiology | Polypyrimidine Tract-Binding Protein - genetics | Proteins | Antiretroviral drugs | Drug therapy | Human immunodeficiency virus--HIV | Infectious Diseases | Viruses | Homo (Human) | HIV - AIDS | Molecular Biology - Structural Biology | Human immunodeficiency virus | HIV
Journal Article