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Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 05/2015, Volume 125, Issue 5, pp. 1780 - 1789
Kinase inhibitors have played an increasingly prominent role in the treatment of cancer and other diseases. Currently, more than 25 oncology drugs that target... 
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Immunotherapy - methods | Apoptosis - drug effects | Humans | Substrate Specificity | Drug Resistance, Neoplasm | Neoplasm Proteins - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Neoplasms - genetics | Protein Processing, Post-Translational - drug effects | Drug Design | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Neoplasm Proteins - genetics | Molecular Targeted Therapy - methods | Neoplasms - enzymology | Gene Fusion | Enzyme Activation - drug effects | Neoplasms - drug therapy | Drug Synergism | Point Mutation | Gene Amplification | Signal Transduction - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Oncogene Proteins, Fusion - genetics | Protein Kinase Inhibitors - therapeutic use | Oncogene Proteins, Fusion - antagonists & inhibitors | Signal Transduction - physiology | Protein Kinase Inhibitors - pharmacology | Apoptosis - physiology | Enzyme inhibitors | Physiological aspects | Research | Drug therapy | Phosphotransferases | Health aspects | Cancer | Proteins | Phosphorylation | Gene amplification | Biology | Regulation | Genomes | Mutation | Metastasis | Kinases | Phosphatase | Tumors | Index Medicus | Abridged Index Medicus | Review
Journal Article
Nature biotechnology, ISSN 1546-1696, 03/2014, Volume 32, Issue 4, pp. 347 - 355
Targeted genome editing using engineered nucleases has rapidly gone from being a niche technology to a mainstream method used by many biological researchers... 
Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Genetic Engineering - methods | Rabbits | Animals | Humans | CRISPR-Cas Systems | Clustered Regularly Interspaced Short Palindromic Repeats | Rats | Mice | Genomics - methods | Forecasts and trends | Gene targeting | Research | Genetic screening | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 5/2012, Volume 109, Issue 19, pp. 7535 - 7540
Journal Article
Nature reviews. Drug discovery, ISSN 1474-1784, 10/2010, Volume 9, Issue 10, pp. 775 - 789
Journal Article