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2016, ISBN 1107172160, xi, 440 pages
... are offering, for the first time, cheap and effective methods for editing the human genome. This opens up startling new opportunities as well as significant ethical uncertainty... 
Genomes | Gene targeting | Medicine: General Issues
Book
2017, ISBN 0544716949, xx, 281 pages
Two Berkeley scientists explore the potential of a revolutionary genetics technology capable of easily and affordably manipulating DNA in human embryos to... 
Genetic code | United States | Genetic Research | CRISPR-Cas Systems | Genetics | Genetic engineering | Research | History | Gene Editing
Book
Journal Article
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2018, Volume 1767, pp. 113 - 136
.... Neuroepigenetic editing tools can be applied to distinguish between the mere presence and functional relevance of such modifications to neural transcription and animal behavior... 
Chromatin | Neuroscience | Psychiatric disease | Epigenetic editing | DNA - genetics | Mental Disorders - genetics | Neurons - pathology | Animals | Epigenesis, Genetic | Humans | Gene Editing - methods | Neurons - metabolism | High-Throughput Nucleotide Sequencing - methods | Nervous System Diseases - genetics | Chromatin - genetics
Journal Article
Nature structural & molecular biology, ISSN 1545-9985, 2011, Volume 18, Issue 2, pp. 230 - 236
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2016, Volume 167, Issue 1, pp. 233 - 247.e17
...) enables targeted DNA methylation editing. Targeting of the dCas9-Tet1 or -Dnmt3a fusion protein to methylated or unmethylated promoter sequences caused activation or silencing, respectively, of an endogenous reporter... 
CELLS | CRISPR | DEPENDENT PHOSPHORYLATION | 3D GENOME | DEMETHYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | RESOLUTION | DISEASE | TRANSCRIPTION | GENE-EXPRESSION | REGULATORY LANDSCAPE | CELL BIOLOGY | Brain-Derived Neurotrophic Factor - genetics | Endonucleases - genetics | Epigenesis, Genetic | Endonucleases - metabolism | Recombinant Fusion Proteins - metabolism | DNA (Cytosine-5-)-Methyltransferases - metabolism | DNA-Binding Proteins - metabolism | Clustered Regularly Interspaced Short Palindromic Repeats | Neurons - metabolism | Repressor Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Cell Line | Promoter Regions, Genetic | Bacterial Proteins - genetics | Proto-Oncogene Proteins - genetics | DNA Methylation - genetics | MyoD Protein - metabolism | DNA-Binding Proteins - genetics | DNA (Cytosine-5-)-Methyltransferases - genetics | Animals | Enhancer Elements, Genetic | CCCTC-Binding Factor | CpG Islands | Protein Binding | Recombinant Fusion Proteins - genetics | Bacterial Proteins - metabolism | Gene Editing - methods | Mice | Genome | Animal genetics | Epigenetic inheritance | Promoters (Genetics) | Methyltransferases | Genes | Genomics | DNA | Genetic research | Methylation | Gene expression | Medical research | Neurons | Medicine, Experimental
Journal Article