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1. Fusion genes and cancer
by Kunnumakkara, Ajaikumar B., editor and Roy, Nand Kishor, editor and Padmavathi, Ganesan, editor
2017, ISBN 9813200936, xviii, 414 pages
Genetic aspects | Cancer
Book
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2. Full Text Pericytoma With t(7;12) and ACTB-GLI1 Fusion: Reevaluation of an Unusual Entity and its Relationship to the Spectrum of GLI1 Fusion–related Neoplasms
by Kerr, Darcy A and Pinto, Andre and Subhawong, Ty K and Wilky, Breelyn A and Schlumbrecht, Matthew P and Antonescu, Cristina R and Nielsen, G Petur and Rosenberg, Andrew E
The American journal of surgical pathology, ISSN 0147-5185, 12/2019, Volume 43, Issue 12, pp. 1682 - 1692
Pathology | Life Sciences & Biomedicine | Surgery | Science & Technology | Sarcoma - classification | Sarcoma - secondary | Translocation, Genetic | Bone Neoplasms - therapy | Humans | Middle Aged | Myopericytoma - secondary | Ovarian Neoplasms - pathology | Male | Bone Neoplasms - pathology | Sarcoma - therapy | Actins - genetics | Ovarian Neoplasms - genetics | Ovarian Neoplasms - classification | Myopericytoma - therapy | Adult | Female | Bone Neoplasms - genetics | Cell Differentiation | Sarcoma - genetics | Genetic Predisposition to Disease | Zinc Finger Protein GLI1 - genetics | Gene Fusion | Treatment Outcome | Chromosomes, Human, Pair 7 | Myopericytoma - genetics | Phenotype | Ovarian Neoplasms - therapy | Biomarkers, Tumor - genetics | Chromosomes, Human, Pair 12 | Bone Neoplasms - classification | Myopericytoma - classification | Index Medicus | Myopericytoma | Sarcoma | GLI1 | ACTB | Pericytoma
Journal Article
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3. Full Text TopHat-Fusion: An algorithm for discovery of novel fusion transcripts
by Kim, Daehwan and Salzberg, Steven L
Genome Biology, ISSN 1474-7596, 08/2011, Volume 12, Issue 8, pp. R72 - R72
Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Prostatic Neoplasms - metabolism | Humans | Molecular Sequence Data | Gene Expression Profiling - methods | Gene Fusion | Male | Breast Neoplasms - metabolism | Algorithms | Sequence Analysis, RNA | Base Sequence | Cell Line, Tumor | Female | Software | Index Medicus | Method
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4. Full Text Bimolecular Complementation of Paramyxovirus Fusion and Hemagglutinin-Neuraminidase Proteins Enhances Fusion: Implications for the Mechanism of Fusion Triggering
by Sarah A. Connolly and George P. Leser and Theodore S. Jardetzky and Robert A. Lamb
Journal of Virology, ISSN 0022-538X, 11/2009, Volume 83, Issue 21, pp. 10857 - 10868
Life Sciences & Biomedicine | Science & Technology | Virology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Miscellaneous | Microbiology | Cell Line | Paramyxovirinae - genetics | Viral Fusion Proteins - metabolism | Viral Fusion Proteins - genetics | Humans | Neuraminidase - metabolism | HN Protein - metabolism | Recombinant Fusion Proteins - metabolism | Virus Internalization | Animals | HN Protein - genetics | Gene Expression Regulation, Viral | Virus Attachment | Recombinant Fusion Proteins - genetics | Paramyxovirinae - metabolism | Mutation | Index Medicus | Virus-Cell Interactions
Journal Article
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5. Full Text Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases
by Archer, Stephen L
The New England journal of medicine, ISSN 0028-4793, 12/2013, Volume 369, Issue 23, pp. 2236 - 2251
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Biological and medical sciences | General aspects | Medical sciences | Neoplasms - metabolism | Cardiovascular Diseases - metabolism | Mitochondrial Proteins - metabolism | Humans | Mitochondrial Diseases - metabolism | Nervous System Diseases - metabolism | Adenosine Triphosphate - biosynthesis | Mitochondrial Diseases - physiopathology | Mitochondrial Dynamics - physiology | Mitochondria | Genetic aspects | Research | Gene mutations | Leigh disease | Risk factors | Disease | Pathogenesis | Therapeutic applications | Homeostasis | Mitochondrial DNA | Mutation | Cardiovascular diseases | Endoplasmic reticulum | Cancer | Index Medicus | Abridged Index Medicus
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6. Full Text The clinical heterogeneity of round cell sarcomas with EWSR1/FUS gene fusions: Impact of gene fusion type on clinical features and outcome
by Tsuda, Yusuke and Zhang, Lei and Meyers, Paul and Tap, William D and Healey, John H and Antonescu, Cristina R
Genes chromosomes & cancer, ISSN 1045-2257, 09/2020, Volume 59, Issue 9, pp. 525 - 534
Ewing sarcoma | Ewing‐like sarcoma | gene fusions | EWSR1 | FUS | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | ETS protein | Sarcoma | FUS gene | Gene fusion | FLI-1 protein | Ewing's sarcoma | Tumors | Ewings sarcoma | Metastases | Index Medicus
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7. Full Text Functional annotation of native enhancers with a Cas9-histone demethylase fusion
by Kearns, Nicola A and Pham, Hannah and Tabak, Barbara and Genga, Ryan M and Silverstein, Noah J and Garber, Manuel and Maehr, René
Nature methods, ISSN 1548-7091, 04/2015, Volume 12, Issue 5, pp. 401 - 403
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Biochemical Research Methods | Science & Technology | Recombinant Proteins - metabolism | Embryonic Stem Cells - metabolism | Caspase 9 - metabolism | Bacterial Proteins - genetics | Cells, Cultured | Caspase 9 - drug effects | Histone Demethylases - drug effects | Gene Expression Regulation, Enzymologic | Histone Demethylases - metabolism | Animals | Bacterial Proteins - metabolism | Enhancer Elements, Genetic - genetics | Enhancer Elements, Genetic - physiology | Mice | Histones - metabolism | Genes, Reporter | Neisseria meningitidis - enzymology | Histones | Physiological aspects | Enzymes | Research | Cellular control mechanisms | Cellular biology | Genomics | Stem cells | Index Medicus
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8. Full Text Mammary Analogue Secretory Carcinoma of Salivary Glands: Molecular Analysis of 25 ETV6 Gene Rearranged Tumors With Lack of Detection of Classical ETV6-NTRK3 Fusion Transcript by Standard RT-PCR: Report of 4 Cases Harboring ETV6-X Gene Fusion
by Skálová, Alena and Vanecek, Tomas and Simpson, Roderick H.W and Laco, Jan and Majewska, Hanna and Baneckova, Martina and Steiner, Petr and Michal, Michal
The American journal of surgical pathology, ISSN 0147-5185, 01/2016, Volume 40, Issue 1, pp. 3 - 13
Pathology | Life Sciences & Biomedicine | Surgery | Science & Technology | Immunohistochemistry | Predictive Value of Tests | Prognosis | Proto-Oncogene Proteins c-ets - genetics | Salivary Gland Neoplasms - genetics | Humans | Mammary Analogue Secretory Carcinoma - pathology | Middle Aged | Male | Mammary Analogue Secretory Carcinoma - genetics | Young Adult | Molecular Diagnostic Techniques | Adult | Female | Registries | Mammary Analogue Secretory Carcinoma - chemistry | Genetic Predisposition to Disease | Mammary Analogue Secretory Carcinoma - therapy | Repressor Proteins - genetics | Gene Fusion | In Situ Hybridization, Fluorescence | Reverse Transcriptase Polymerase Chain Reaction | Salivary Gland Neoplasms - chemistry | Oncogene Proteins, Fusion - genetics | Gene Rearrangement | Salivary Gland Neoplasms - therapy | Adolescent | Aged | Biomarkers, Tumor - genetics | Salivary Gland Neoplasms - pathology | Index Medicus
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9. Full Text Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer
by Lovly, Christine M and Lovly, Christine M and McDonald, Nerina T and McDonald, Nerina T and Chen, Heidi and Chen, Heidi and Ortiz-Cuaran, Sandra and Ortiz-Cuaran, Sandra and Heukamp, Lukas C and Heukamp, Lukas C and Yan, Yingjun and Yan, Yingjun and Florin, Alexandra and Florin, Alexandra and Ozretić, Luka and Ozretić, Luka and Lim, Diana and Lim, Diana and Wang, L and Wang, Lu and Chen, Zhao and Chen, Zhao and Chen, X and Chen, Xi and Lu, Pengcheng and Lu, Pengcheng and Paik, Paul K and Paik, Paul K and Shen, Ronglai and Shen, Ronglai and Jin, Hailing and Jin, Hailing and Buettner, Reinhard and Buettner, Reinhard and Ansén, Sascha and Ansén, Sascha and Perner, Sven and Perner, Sven and Brockmann, Michael and Brockmann, Michael and Bos, Marc and Bos, Marc and Wolf, Jürgen and Wolf, Jürgen and Gardizi, Masyar and Gardizi, Masyar and Wright, Gavin M and Wright, Gavin M and Solomon, Benjamin and Solomon, Benjamin and Russell, Prudence A and Russell, Prudence A and Rogers, Toni-Maree and Rogers, Toni-Maree and Suehara, Yoshiyuki and Suehara, Yoshiyuki and Red-Brewer, Monica and Red-Brewer, Monica and Tieu, Rudy and Tieu, Rudy and de Stanchina, Elisa and De Stanchina, Elisa and Wang, Qingguo and Wang, Qingguo and Zhao, Zhongming and Zhao, Zhongming and Johnson, David H and Johnson, David H and Horn, Leora and Horn, Leora and Wong, Kwok-Kin and Wong, Kwok-Kin and Thomas, Roman K and Thomas, Roman K and Ladanyi, Marc and Ladanyi, Marc and Pao, William and Pao, William
Nature medicine, ISSN 1078-8956, 2014, Volume 20, Issue 9, pp. 1027 - 1034
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Lung Neoplasms - drug therapy | Receptor, IGF Type 1 - metabolism | Up-Regulation | Pyrazoles - therapeutic use | Lung Neoplasms - enzymology | Humans | Lung Neoplasms - metabolism | Middle Aged | Receptor Protein-Tyrosine Kinases - drug effects | Gene Knockdown Techniques | Receptor, IGF Type 1 - drug effects | Female | Pyridines - pharmacology | Insulin Receptor Substrate Proteins - genetics | Pyrazoles - pharmacology | Pyridines - therapeutic use | Case studies | Care and treatment | Control | Drug resistance | Lung cancer | Patient outcomes | Kinases | Neurons | Fusion | Lymphoma | Index Medicus | ALK | lung cancer | crizotinib | IRS-1 | ALK fusions | exceptional responder | cancer | tyrosine kinase inhibitor | drug resistance | IGF-1R | ceritinib | targeted therapeutics
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10. Full Text Cabozantinib overcomes crizotinib resistance in ROS1 fusion-positive cancer
by Katayama, Ryohei and Kobayashi, Yuka and Friboulet, Luc and Lockerman, Elizabeth L and Koike, Sumie and Shaw, Alice T and Engelman, Jeffrey A and Fujita, Naoya
Clinical cancer research, ISSN 1078-0432, 01/2015, Volume 21, Issue 1, pp. 166 - 174
Life Sciences & Biomedicine | Oncology | Science & Technology | Antigens, Differentiation, B-Lymphocyte - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Pyridines - administration & dosage | Carcinoma, Non-Small-Cell Lung - genetics | Humans | Histocompatibility Antigens Class II - biosynthesis | Proto-Oncogene Proteins - genetics | Proto-Oncogene Proteins - biosynthesis | Protein Kinase Inhibitors - administration & dosage | Drug Resistance, Neoplasm - genetics | Protein-Tyrosine Kinases - genetics | Pyrazoles - administration & dosage | Anilides - administration & dosage | Oncogene Proteins, Fusion - genetics | Antigens, Differentiation, B-Lymphocyte - biosynthesis | Cell Line, Tumor | Carcinoma, Non-Small-Cell Lung - drug therapy | Gene Expression Regulation, Neoplastic - drug effects | Histocompatibility Antigens Class II - genetics | Mutation | Protein-Tyrosine Kinases - biosynthesis | Drug Resistance, Neoplasm - drug effects | Index Medicus | ROS1 rearrangement | crizotinib | mutagenesis | resistance | cabozantinib
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