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2009, Advances in experimental medicine and biology, ISBN 9781441911445, Volume 656, xvi, 131
The Apc protein is a multifunctional participant in a diverse array of cellular functions... 
Adenomatous Polyposis Coli | Colorectal Neoplasms | Colon (Anatomy) | metabolism | Adenomatous Polyposis Coli Protein | Tumor suppressor proteins | Genes, APC | Cancer
Book
Human molecular genetics, ISSN 1460-2083, 04/2001, Volume 10, Issue 7, pp. 721 - 733
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 03/2010, Volume 464, Issue 7291, pp. 1058 - 1061
.... We show that a deficiency in the adenomatous polyposis coli (APC) gene and subsequent activation of beta-catenin lead to the repression of cellular caspase-8 inhibitor c-FLIP (also known... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Vitamin A - pharmacology | Apoptosis - drug effects | Vitamin A - analogs & derivatives | Colorectal Neoplasms - genetics | Humans | Precancerous Conditions - metabolism | Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism | Genes, APC | Vitamin A - administration & dosage | Precancerous Conditions - drug therapy | Intestinal Polyps - drug therapy | TNF-Related Apoptosis-Inducing Ligand - pharmacology | Time Factors | Precancerous Conditions - pathology | CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism | Colorectal Neoplasms - metabolism | Adenomatous Polyposis Coli Protein - genetics | TNF-Related Apoptosis-Inducing Ligand - administration & dosage | Mice, Inbred C57BL | Colorectal Neoplasms - prevention & control | Survival Rate | Precancerous Conditions - genetics | Proto-Oncogene Proteins c-myc - metabolism | TNF-Related Apoptosis-Inducing Ligand - therapeutic use | beta Catenin - metabolism | Gene Expression Regulation - drug effects | Vitamin A - therapeutic use | Animals | Signal Transduction - drug effects | Intestinal Polyps - pathology | Cell Proliferation - drug effects | Mice | Colorectal Neoplasms - pathology | Adenomatous Polyposis Coli Protein - deficiency | Prevention | Chemoprevention | Colorectal cancer | Physiological aspects | Development and progression | Genetic aspects | Polyposis, Familial | Research | Methods | Apoptosis | Proteins | Stem cells | Index Medicus | Receptors | Inhibitors | Tumours | Activation | Colon | Acetates | Cancer
Journal Article