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Journal Article
Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9737, pp. 235 - 244
Journal Article
Gynecologic Oncology, ISSN 0090-8258, 2015, Volume 137, Issue 3, pp. 386 - 391
Abstract Background Veliparib is a potent small molecule inhibitor of PARP-1/2, which is cytotoxic in tumor cells with deficiencies in BRCA1 or BRCA2 . We... 
Hematology, Oncology and Palliative Medicine | Obstetrics and Gynecology | BRCA1, BRCA2 mutation | Toxicity | Veliparib | PARP inhibitor | Phase II trial | Ovarian cancer | SENSITIVITY | OPEN-LABEL | COMBINATION | PLATINUM-FREE INTERVAL | SOMATIC MUTATIONS | OBSTETRICS & GYNECOLOGY | OLAPARIB | ONCOLOGY | RESISTANCE | HOMOLOGOUS RECOMBINATION | REFRACTORY SOLID TUMORS | POLY(ADP-RIBOSE) POLYMERASE INHIBITOR | Humans | Middle Aged | Neoplasm Recurrence, Local - drug therapy | Ovarian Neoplasms - genetics | BRCA1 Protein - genetics | Neoplasms, Glandular and Epithelial - genetics | Peritoneal Neoplasms - drug therapy | Peritoneal Neoplasms - genetics | Fallopian Tube Neoplasms - genetics | Neoplasms, Glandular and Epithelial - drug therapy | Aged, 80 and over | Carcinoma, Ovarian Epithelial | Genes, BRCA2 | Germ-Line Mutation | Adult | Female | Neoplasm Recurrence, Local - genetics | Aged | Genes, BRCA1 | Benzimidazoles - adverse effects | Ovarian Neoplasms - drug therapy | BRCA2 Protein - genetics | Benzimidazoles - therapeutic use | Fallopian Tube Neoplasms - drug therapy | Medical research | Cancer patients | Care and treatment | Gene mutations | Analysis | Medicine, Experimental | Genetic aspects | Cancer | Chemotherapy | Clinical trials | Index Medicus | toxicity | BRCA2 mutation | ovarian cancer | veliparib | BRCA1
Journal Article
Lancet, The, ISSN 0140-6736, 2010, Volume 376, Issue 9737, pp. 245 - 251
Journal Article
Journal Article
by Antoniou, Antonis C and Sinilnikova, Olga M and Simard, Jacques and Léoné, Mélanie and Dumont, Martine and Neuhausen, Susan L and Struewing, Jeffery P and Stoppa-Lyonnet, Dominique and Barjhoux, Laure and Hughes, David J and Coupier, Isabelle and Belotti, Muriel and Lasset, Christine and Bonadona, Valérie and Bignon, Yves-Jean and Rebbeck, Timothy R and Wagner, Theresa and Lynch, Henry T and Domchek, Susan M and Nathanson, Katherine L and Garber, Judy E and Weitzel, Jeffrey and Narod, Steven A and Tomlinson, Gail and Olopade, Olufunmilayo I and Godwin, Andrew and Isaacs, Claudine and Jakubowska, Anna and Lubinski, Jan and Gronwald, Jacek and Górski, Bohdan and Byrski, Tomasz and Huzarski, Tomasz and Peock, Susan and Cook, Margaret and Baynes, Caroline and Murray, Alexandra and Rogers, Mark and Daly, Peter A and Dorkins, Huw and Schmutzler, Rita K and Versmold, Beatrix and Engel, Christoph and Meindl, Alfons and Arnold, Norbert and Niederacher, Dieter and Deissler, Helmut and Spurdle, Amanda B and Chen, Xiaoqing and Waddell, Nicola and Cloonan, Nicole and Kirchhoff, Tomas and Offit, Kenneth and Friedman, Eitan and Kaufmann, Bella and Laitman, Yael and Galore, Gilli and Rennert, Gad and Lejbkowicz, Flavio and Raskin, Leon and Andrulis, Irene L and Ilyushik, Eduard and Ozcelik, Hilmi and Devilee, Peter and Vreeswijk, Maaike P.G and Greene, Mark H and Prindiville, Sheila A and Osorio, Ana and Benítez, Javier and Zikan, Michal and Szabo, Csilla I and Kilpivaara, Outi and Nevanlinna, Heli and Hamann, Ute and Durocher, Francine and Arason, Adalgeir and Couch, Fergus J and Easton, Douglas F and Chenevix-Trench, Georgia and Kathleen Cuningham Consortium for Research into Familial Breast Cancer (kConFab) and German Consortium for Hereditary Breast and Ovarian Cancer (GCHBOC) and Genetic Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers Study (GEMO) and Epidemiological Study of BRCA1 and BRCA2 Mutation Carriers (EMBRACE) and Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)
The American Journal of Human Genetics, ISSN 0002-9297, 2007, Volume 81, Issue 6, pp. 1186 - 1200
Journal Article
JAMA - Journal of the American Medical Association, ISSN 0098-7484, 01/2019, Volume 321, Issue 1, pp. 27 - 28
The BRCA1 and BRCA2 act as biological markers for early detection of breast and ovarian cancer in women. The risks and benefits of mastectomy before... 
BREAST-CANCER | MEDICINE, GENERAL & INTERNAL | Care and treatment | Usage | Gene mutations | Mastectomy | Breast cancer | Genetic aspects | Research | Biological markers | Risk factors | Genetic screening | Ovarian cancer | Carriers | BRCA2 protein | Chemotherapy | BRCA1 protein | Health risks | Risk reduction | Risk | Mutation | Cancer | Index Medicus | Abridged Index Medicus
Journal Article