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Journal Article
PLoS ONE, ISSN 1932-6203, 11/2017, Volume 12, Issue 11, pp. e0187314 - e0187314
Human cancers are known to downregulate Major Histocompatibility Complex (MHC) class I expression thereby escaping recognition and rejection by anti-tumor T... 
IMMUNOGENICITY | GENE | MICROENVIRONMENT | IMMUNOTHERAPY | MULTIDISCIPLINARY SCIENCES | MELANOMA-CELLS | FACTOR (HIF)-1-ALPHA | EXPRESSION | CANCER | CARCINOMA | PEPTIDE TRANSPORTER | ATP-Binding Cassette Sub-Family B Member 2 - immunology | Kidney Neoplasms - genetics | Transcriptional Activation - genetics | Cell Hypoxia - immunology | Humans | Gene Expression Regulation, Neoplastic | Kidney Neoplasms - immunology | Hypoxia-Inducible Factor 1 - immunology | ATP-Binding Cassette Sub-Family B Member 2 - genetics | Transcriptional Activation - immunology | Antigen-Presenting Cells - immunology | Oxygen - metabolism | Hypoxia-Inducible Factor 1 - genetics | Proteasome Endopeptidase Complex - genetics | Tumor Microenvironment - immunology | Antigen-Presenting Cells - pathology | Von Hippel-Lindau Tumor Suppressor Protein - immunology | Tumor Microenvironment - genetics | Genes, MHC Class I - immunology | Kidney Neoplasms - pathology | T-Lymphocytes - immunology | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Proteasome Endopeptidase Complex - immunology | Physiological aspects | Transcription factors | Genetic aspects | Major histocompatibility complex | Research | T cells | Biotechnology | Cell culture | Transcription | Peptides | Lymphocytes T | Biology | Vaccines | Proteins | Cancer vaccines | Cell recognition | Lymphocytes | Hypoxia-inducible factors | Antigen presentation | Medical research | Antigens | Oxygen | Kidneys | Tumor cells | Cultures | Inflammation | siRNA | Epitopes | Gene expression | Hyperoxia | Hypoxia | VHL protein | Mutation | Oxygen tension | Neoplasia | Histocompatibility | Clear cell-type renal cell carcinoma | Recognition | Kidney transplantation | Tumors | Cancer | Index Medicus
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2017, Volume 114, Issue 40, pp. E8440 - E8447
Journal Article
European Journal of Immunology, ISSN 0014-2980, 09/2012, Volume 42, Issue 9, pp. 2505 - 2510
Journal Article
Journal Article
Parasitology, ISSN 0031-1820, 03/2018, Volume 145, Issue 3, pp. 292 - 306
Immunoactivation depends upon the antigen potential to modulate T-cell repertoires. The present study has enumerated the effect of 61 kDa recombinant... 
innate immunity | co-factor-independent phosphoglycerate mutase | visceral leishmaniasis | Leishmania donovani | adaptive immunity | PROTEIN | IFN-GAMMA | MODEL | PEPTIDE | IMMUNIZATION | RESPONSES | IMMUNOGENICITY | DATABASE | MICE | PARASITOLOGY | Interleukin-1beta - drug effects | Coenzymes - genetics | Humans | Genes, MHC Class II - immunology | Leishmaniasis, Visceral - immunology | NF-kappa B p50 Subunit - genetics | NF-kappa B p50 Subunit - drug effects | Macrophages - parasitology | Th1 Cells | Computer Simulation | Genes, MHC Class I - immunology | Leukocytes, Mononuclear - immunology | Coenzymes - deficiency | Epitopes, T-Lymphocyte - drug effects | Epitopes, T-Lymphocyte - immunology | Macrophages - immunology | Cytokines - immunology | Cell Line | Leishmania donovani - immunology | Leukocytes, Mononuclear - drug effects | Phosphoglycerate Mutase - pharmacology | Interleukin-1beta - immunology | Leishmania donovani - enzymology | Leukocytes, Mononuclear - parasitology | Nitric Oxide Synthase Type II - drug effects | Recombinant Proteins - genetics | Nitric Oxide | Phosphoglycerate Mutase - genetics | Recombinant Proteins - pharmacology | Cytokines - drug effects | Phosphoglycerate Mutase - immunology | Recombinant Proteins - immunology | Lymphocyte Activation - drug effects | Macrophages | Lymphocytes T | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 3868 - 10
Understanding mechanisms of late/acquired cancer immunotherapy resistance is critical to improve outcomes; cellular immunotherapy trials offer a means to probe... 
SURVIVAL | POLYOMAVIRUS | PEMBROLIZUMAB | ADVANCED MELANOMA | PD-1 BLOCKADE | MULTIDISCIPLINARY SCIENCES | TUMOR-REGRESSION | DOWN-REGULATION | MERKEL-CELL-CARCINOMA | EXPRESSION | T-CELLS | Polyomavirus Infections - immunology | Tumor Virus Infections - genetics | Tumor Escape - genetics | Tumor Virus Infections - virology | CD8-Positive T-Lymphocytes - transplantation | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Carcinoma, Merkel Cell - therapy | Male | Testicular Neoplasms - secondary | Neoplasm Recurrence, Local - immunology | Carcinoma, Merkel Cell - immunology | Single-Cell Analysis - methods | Genes, MHC Class I - immunology | Tumor Virus Infections - immunology | Tumor Virus Infections - therapy | Costimulatory and Inhibitory T-Cell Receptors - antagonists & inhibitors | Merkel cell polyomavirus - isolation & purification | Immunotherapy, Adoptive - methods | Skin Neoplasms - immunology | Skin Neoplasms - therapy | Carcinoma, Merkel Cell - genetics | Genes, MHC Class I - genetics | Lymphocytes, Tumor-Infiltrating - transplantation | Transplantation, Autologous - methods | Merkel cell polyomavirus - immunology | Testicular Neoplasms - virology | Sequence Analysis, RNA - methods | Testicular Neoplasms - immunology | Antineoplastic Agents, Immunological - therapeutic use | Polyomavirus Infections - virology | Skin Neoplasms - genetics | Skin Neoplasms - virology | Polyomavirus Infections - genetics | Polyomavirus Infections - therapy | Transcription, Genetic - immunology | Carcinoma, Merkel Cell - virology | Neoplasm Recurrence, Local - genetics | CD8-Positive T-Lymphocytes - immunology | Lymphocytes, Tumor-Infiltrating - immunology | Transcription | CD8 antigen | Clinical trials | Lymphocytes T | Ribonucleic acid--RNA | Immunosuppressive agents | Gene sequencing | Metastases | Interfaces | Inhibitors | Immune checkpoint | Lymphocytes | Immunotherapy | Infiltration | Histocompatibility antigen HLA | Tumors | Cancer | Index Medicus
Journal Article