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Molecular cancer therapeutics, ISSN 1535-7163, 2001
Journal
Nature cell biology, ISSN 1476-4679, 2018, Volume 20, Issue 8, pp. 954 - 965
.... 3Genome Integrity, Immunity and Cancer Unit, Department of Immunology, Department of Genomes and Genetics, Institut Pasteur, Paris, France. 4Division of Oncogenomics... 
PATHWAY CHOICE | STRAND BREAK REPAIR | RESECTION | DAMAGE-RESPONSE | 53BP1 | CLASS-SWITCH RECOMBINATION | FANCONI-ANEMIA | DIFFERENTIAL EXPRESSION ANALYSIS | POLYMERASE-ZETA | TELOMERES | CELL BIOLOGY | Osteosarcoma - drug therapy | Mad2 Proteins - metabolism | Humans | Multiprotein Complexes | Ovarian Neoplasms - pathology | Bone Neoplasms - pathology | DNA Breaks, Double-Stranded | Bone Neoplasms - metabolism | Breast Neoplasms - metabolism | Dose-Response Relationship, Drug | Ovarian Neoplasms - genetics | Telomere-Binding Proteins - genetics | DNA End-Joining Repair | HEK293 Cells | Female | Bone Neoplasms - genetics | Ovarian Neoplasms - metabolism | Bone Neoplasms - drug therapy | BRCA1 Protein - deficiency | Telomere-Binding Proteins - metabolism | Ovarian Neoplasms - drug therapy | Osteosarcoma - metabolism | DNA-Binding Proteins | Tumor Suppressor p53-Binding Protein 1 - metabolism | Recombinational DNA Repair | Tumor Suppressor p53-Binding Protein 1 - genetics | Cisplatin - pharmacology | Breast Neoplasms - drug therapy | Proteins - genetics | Xenograft Model Antitumor Assays | BRCA1 Protein - genetics | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | Drug Resistance, Neoplasm - genetics | Animals | Breast Neoplasms - genetics | Proteins - metabolism | Breast Neoplasms - pathology | Mad2 Proteins - genetics | Cell Line, Tumor | Mice | Osteosarcoma - genetics | Cell Cycle Proteins | Osteosarcoma - pathology | Care and treatment | DNA | Cancer cells | Breast cancer | Genetic aspects | Research | Gene expression | Single-stranded DNA | DNA damage | Homologous recombination | Poly(ADP-ribose) | Homology | Genomes | Inactivation | Proteins | Ribose | Null cells | Deoxyribonucleic acid--DNA | BRCA2 protein | CRISPR | Deactivation | BRCA1 protein | Poly(ADP-ribose) polymerase | Adenosine diphosphate | Oligosaccharides | Double-strand break repair | Screens | Cisplatin | Inhibitors | Prostate | Viability | Tumors | Telomere-Binding Proteins / metabolism | Osteosarcoma / genetics | Telomere-Binding Proteins / genetics | BRCA1 Protein / genetics | Cellular Biology | Genetics | Proteins / genetics | Osteosarcoma / drug therapy | Ovarian Neoplasms / genetics | Mad2 Proteins / genetics | Proteins / metabolism | Breast Neoplasms / drug therapy | Breast Neoplasms / metabolism | Tumor Suppressor p53-Binding Protein 1 / genetics | BRCA1 Protein / deficiency | Ovarian Neoplasms / metabolism | Mad2 Proteins / metabolism | Breast Neoplasms / pathology | Bone Neoplasms / genetics | Ovarian Neoplasms / pathology | Bone Neoplasms / pathology | Life Sciences | Bone Neoplasms / drug therapy | Ovarian Neoplasms / drug therapy | Osteosarcoma / metabolism | Biochemistry, Molecular Biology | Breast Neoplasms / genetics | Drug Resistance, Neoplasm / genetics | Osteosarcoma / pathology | Bone Neoplasms / metabolism | Poly(ADP-ribose) Polymerase Inhibitors / pharmacology | Cisplatin / pharmacology | Molecular biology | Tumor Suppressor p53-Binding Protein 1 / metabolism | Cancer
Journal Article
Cancer genetics and cytogenetics, ISSN 0165-4608
Journal
BMC genomics, ISSN 1471-2164, 04/2006, Volume 7, Issue 1, pp. 90 - 90
Background: Post-translational modification of histones resulting in chromatin remodelling plays a key role in the regulation of gene expression. Here we... 
BREAST-CANCER | CBP | METHYLATION | INHIBITION | BOOTSTRAP | ACETYLATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | PATTERNS | MUTATIONS | REPRODUCIBILITY | PROGRESSION | Neoplasms - metabolism | Protein Methyltransferases | Pancreatic Neoplasms - metabolism | Colorectal Neoplasms - genetics | Histone Acetyltransferases - biosynthesis | Humans | Lung Neoplasms - metabolism | Protein Processing, Post-Translational - genetics | DNA, Complementary - genetics | Gene Expression Regulation, Neoplastic | Histone Acetyltransferases - genetics | Male | Histone-Lysine N-Methyltransferase - biosynthesis | Breast Neoplasms - metabolism | Ovarian Neoplasms - genetics | Polymorphism, Single-Stranded Conformational | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Polymerase Chain Reaction | Female | Ovarian Neoplasms - metabolism | Neoplasm Proteins - genetics | Colorectal Neoplasms - metabolism | Lung Neoplasms - genetics | Histone-Lysine N-Methyltransferase - genetics | Histone Deacetylases - genetics | Neoplasm Proteins - biosynthesis | Linear Models | Pancreatic Neoplasms - genetics | Gene Expression Regulation, Enzymologic | Breast Neoplasms - genetics | Carcinoma - genetics | Carcinoma - metabolism | DNA, Neoplasm - genetics | Histones - metabolism | Histone Code - genetics | Cluster Analysis
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 12/2007, Volume 117, Issue 12, pp. 3660 - 3663
in this issue of the JCI, two reports provide intriguing new information on the role of the inflammatory cytokine IL-6 in breast and lung cancer. The study by... 
BREAST-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | LUNG-CANCER | PATHWAY | STAT3 | NOTCH | STEM/PROGENITOR CELLS | GROWTH-FACTOR | INTERLEUKIN-6 | IDENTIFICATION | TUMORIGENESIS | Receptor, Epidermal Growth Factor - genetics | Transcription, Genetic - drug effects | Interleukin-6 - antagonists & inhibitors | Carbonic Anhydrases - biosynthesis | Cytokine Receptor gp130 - genetics | Receptors, Notch - metabolism | Humans | Lung Neoplasms - metabolism | Antigens, Neoplasm - biosynthesis | Spheroids, Cellular - pathology | Neoplasm Proteins - pharmacology | Receptors, Notch - genetics | Janus Kinases - metabolism | RNA, Messenger - metabolism | Serrate-Jagged Proteins | Phosphorylation - drug effects | Neoplasm Proteins - genetics | Interleukin-6 - metabolism | Gene Expression Regulation, Neoplastic - genetics | STAT3 Transcription Factor - genetics | Cytokine Receptor gp130 - metabolism | Interleukin-6 - genetics | Membrane Proteins - genetics | Spheroids, Cellular - metabolism | Enzyme Inhibitors - pharmacology | Mammary Glands, Human - pathology | Lung Neoplasms - therapy | Signal Transduction - genetics | Autocrine Communication - genetics | Breast Neoplasms - genetics | RNA, Neoplasm - biosynthesis | Signal Transduction - drug effects | Mice, Nude | Cell Line, Tumor | RNA, Neoplasm - genetics | Stem Cells - pathology | Carcinoma - genetics | Mice | Mutation | Transcription, Genetic - genetics | Cell Hypoxia - genetics | Calcium-Binding Proteins - genetics | Neoplasm Transplantation | Carbonic Anhydrases - genetics | Lung Neoplasms - pathology | Autocrine Communication - drug effects | Mammary Glands, Human - metabolism | Neoplasm Proteins - metabolism | Stem Cells - metabolism | Breast Neoplasms - metabolism | Breast Neoplasms - therapy | Intercellular Signaling Peptides and Proteins - metabolism | Receptor, Epidermal Growth Factor - metabolism | Female | Membrane Proteins - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Carcinoma - pathology | STAT3 Transcription Factor - metabolism | Carbonic Anhydrase IX | Calcium-Binding Proteins - metabolism | Lung Neoplasms - genetics | Antigens, Neoplasm - genetics | Cell Hypoxia - drug effects | Janus Kinases - genetics | Neoplasm Invasiveness | RNA, Messenger - genetics | RNA, Small Interfering - pharmacology | Intercellular Signaling Peptides and Proteins - genetics | Up-Regulation - genetics | Up-Regulation - drug effects | Animals | Interleukin-6 - pharmacology | Breast Neoplasms - pathology | Interleukin-6 - biosynthesis | Carcinoma - therapy | Receptor, Notch3 | Carcinoma - metabolism | Antagonists (Biochemistry) | Epithelial tumors | Dosage and administration | Diagnosis | Research | Drug therapy | Health aspects | Interleukin-6
Journal Article
Genes, chromosomes & cancer, ISSN 1098-2264, 1989
Journal
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2011, Volume 331, Issue 6017, pp. 593 - 596
Satellite repeats in heterochromatin are transcribed into noncoding RNAs that have been linked to gene silencing and maintenance of chromosomal integrity.... 
Tumor cell line | Artificial satellites | RNA | Lungs | Genes | Liver | REPORTS | Cell lines | Pancreas | Tumors | Cancer | RNAS | ELEMENTS | DIFFERENTIATION | DATABASE | PERVASIVE TRANSCRIPTION | MULTIDISCIPLINARY SCIENCES | Colonic Neoplasms - genetics | RNA, Untranslated - metabolism | Humans | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Male | Gene Expression Profiling | RNA, Neoplasm - metabolism | RNA, Untranslated - genetics | Heterochromatin - chemistry | Carcinoma, Pancreatic Ductal - genetics | Ovarian Neoplasms - genetics | DNA Methylation | Carcinoma in Situ - genetics | Prostatic Neoplasms - genetics | Neoplasms - genetics | Neurosecretory Systems - metabolism | Female | Transcription, Genetic | Lung Neoplasms - genetics | Prostatic Neoplasms - pathology | Gene Expression | Carcinoma in Situ - pathology | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Carcinoma, Pancreatic Ductal - pathology | Animals | Heterochromatin - genetics | Long Interspersed Nucleotide Elements | Mice, Nude | Colonic Neoplasms - pathology | RNA, Neoplasm - genetics | DNA, Satellite - genetics | Mice | DNA, Neoplasm - genetics | Neoplasms - pathology | Epithelial cells | Analysis | Microsatellites (Genetics) | Genetic aspects | Gene expression | Health aspects | Biomarkers | Chromatin | Pancreatic cancer | Deoxyribonucleic acid--DNA
Journal Article
Blood, ISSN 1528-0020, 2012, Volume 119, Issue 24, pp. 5795 - 5806
The pathogenesis of hepatosplenic T-cell lymphoma (HSTL), a rare entity mostly derived from γδ T cells and usually with a fatal outcome, remains largely... 
GAMMA-DELTA | TYROSINE KINASE | ALPHA-BETA | NON-HODGKINS-LYMPHOMA | NK-CELL | PI EXPRESSION | RECEPTOR | DRUG-RESISTANCE | HEMATOLOGY | NF-KAPPA-B | CLINICOPATHOLOGICAL ENTITY | Crystallins - metabolism | Protein-Tyrosine Kinases - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Male | Receptors, Antigen, T-Cell, gamma-delta - genetics | Gene Expression Profiling | Intracellular Signaling Peptides and Proteins - metabolism | Molecular Targeted Therapy | Young Adult | Base Sequence | Biomarkers, Tumor - metabolism | Adult | Female | Liver Neoplasms - pathology | Membrane Proteins - metabolism | Genes, Neoplasm - genetics | Syk Kinase | Cell Lineage - genetics | Splenic Neoplasms - drug therapy | Liver Neoplasms - genetics | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Splenic Neoplasms - genetics | Liver Neoplasms - drug therapy | Lymphoma, T-Cell - genetics | Receptors, Antigen, T-Cell, alpha-beta - genetics | Isochromosomes - genetics | Drug Resistance, Neoplasm - genetics | Lymphoma, T-Cell - drug therapy | Splenic Neoplasms - pathology | Chromosome Aberrations | Lymphoma, T-Cell - pathology | Aged | Biomarkers, Tumor - genetics | Cluster Analysis | Protein-Tyrosine Kinases - antagonists & inhibitors | pathology | Lymphoma, T-Cell | Genes, Neoplasm | Drug Resistance, Neoplasm | Isochromosomes | Liver Neoplasms | genetics | Crystallins | Receptors, Antigen, T-Cell, alpha-beta | drug therapy | Tumor Markers, Biological | Intracellular Signaling Peptides and Proteins | antagonists & inhibitors | Membrane Proteins | Cell Lineage | Receptors, Antigen, T-Cell, gamma-delta | metabolism | Protein-Tyrosine Kinases | Splenic Neoplasms
Journal Article
Nature (London), ISSN 1476-4687, 2014, Volume 513, Issue 7518, pp. 382 - 387
Journal Article
Seminars in oncology, ISSN 0093-7754, 2015, Volume 42, Issue 6, pp. 801 - 819
The fibroblast growth factor receptor (FGFR) pathway plays a major role in several biological processes, from organogenesis to metabolism homeostasis and... 
BREAST-CANCER | LUNG-CANCER | IN-VITRO | ONCOLOGY | SQUAMOUS-CELL CARCINOMA | RESISTANCE | GENE AMPLIFICATION | POTENTIAL THERAPEUTIC TARGET | PROGNOSTIC-SIGNIFICANCE | ANTITUMOR-ACTIVITY | EXPRESSION | Neoplasms - metabolism | Gastrointestinal Neoplasms - genetics | Gastrointestinal Neoplasms - drug therapy | Humans | Brain Neoplasms - pathology | Fibroblast Growth Factors - genetics | Brain Neoplasms - metabolism | Head and Neck Neoplasms - metabolism | Breast Neoplasms - metabolism | Fibroblast Growth Factors - metabolism | Gastrointestinal Neoplasms - pathology | Glioblastoma - genetics | Receptors, Fibroblast Growth Factor - genetics | Female | Glioblastoma - metabolism | Antineoplastic Agents - pharmacology | Molecular Targeted Therapy - methods | Gastrointestinal Neoplasms - metabolism | Biomarkers, Tumor - analysis | Head and Neck Neoplasms - drug therapy | Receptors, Fibroblast Growth Factor - antagonists & inhibitors | Thoracic Neoplasms - pathology | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | Breast Neoplasms - drug therapy | Thoracic Neoplasms - metabolism | Head and Neck Neoplasms - pathology | Neoplasms - drug therapy | Breast Neoplasms - genetics | Thoracic Neoplasms - genetics | Breast Neoplasms - pathology | Glioblastoma - pathology | Receptors, Fibroblast Growth Factor - metabolism | Head and Neck Neoplasms - genetics | Fibroblast Growth Factors - antagonists & inhibitors | Thoracic Neoplasms - drug therapy | Glioblastoma - drug therapy | Neoplasms - pathology | Drug Resistance, Neoplasm - physiology | Drug Resistance, Neoplasm - drug effects | Index Medicus
Journal Article
Cancer gene therapy, ISSN 0929-1903, 1994
Journal
Cell stem cell, ISSN 1934-5909, 2010, Volume 6, Issue 6, pp. 603 - 615
Recent evidence suggests that a subpopulation of cancer cells, cancer stem cells (CSCs), is responsible for tumor growth in colorectal cancer. However,... 
STEMCELL | CELLCYCLE | BREAST-CANCER | INITIATING CELLS | DIPEPTIDYL-PEPTIDASE-IV | CARCINOMA CELLS | EXTRACELLULAR-MATRIX | ACUTE MYELOID-LEUKEMIA | E-CADHERIN | IDENTIFICATION | TUMOR-GROWTH | HUMAN PANCREATIC-CANCER | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Neoplasm Transplantation | RNA, Small Interfering - genetics | Prognosis | Follow-Up Studies | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Colorectal Neoplasms - genetics | Humans | Apoptosis - genetics | Gene Expression Profiling | Colorectal Neoplasms - diagnosis | Organoplatinum Compounds - pharmacology | Neoplastic Stem Cells - metabolism | Cell Transformation, Neoplastic - genetics | Colorectal Neoplasms - drug therapy | Liver Neoplasms - physiopathology | Neoplastic Stem Cells - pathology | Tumor Burden - genetics | Tumor Cells, Cultured | Liver Neoplasms - secondary | Colorectal Neoplasms - metabolism | Carcinoma - secondary | Carcinoma - drug therapy | Liver Neoplasms - genetics | Dipeptidyl Peptidase 4 - biosynthesis | Liver Neoplasms - drug therapy | Carcinoma - diagnosis | Dipeptidyl Peptidase 4 - genetics | Mice, SCID | Carcinoma - physiopathology | Disease Progression | Colorectal Neoplasms - physiopathology | Drug Resistance, Neoplasm - genetics | Animals | Liver Neoplasms - diagnosis | Tumor Burden - drug effects | Liver Neoplasms - metabolism | Carcinoma - genetics | Biomarkers, Tumor - genetics | Fluorouracil - pharmacology | Mice | Carcinoma - metabolism | Colorectal Neoplasms - pathology | Neoplasm Invasiveness - genetics | Cell Migration Assays | Biomarkers, Tumor - biosynthesis
Journal Article