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International Journal of Cancer, ISSN 0020-7136, 08/2008, Volume 123, Issue 3, pp. 552 - 560
Genistein is a phytoestrogen that has been reported to suppress the AKT signaling pathway in several malignancies. However, the molecular mechanism of... 
Prostate cancer | Genistein | Tumor suppressor gene | APOPTOSIS | METHYLATION | PROTEIN-KINASE | TRANSCRIPTION | SIRT1 | FACULTATIVE HETEROCHROMATIN | CYLD | prostate cancer | genistein | ONCOLOGY | SIGNALING PATHWAY | NF-KAPPA-B | EXPRESSION | tumor suppressor gene | PTEN Phosphohydrolase - drug effects | Prostatic Neoplasms - metabolism | Deubiquitinating Enzyme CYLD | CpG Islands - drug effects | Humans | Male | NF-kappa B - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Genes, Tumor Suppressor - drug effects | Genes, p53 - drug effects | Prostatic Neoplasms - genetics | Chromatin Immunoprecipitation | Forkhead Transcription Factors - metabolism | Sirtuin 1 | Antimetabolites, Antineoplastic - pharmacology | Electrophoretic Mobility Shift Assay | Gene Expression Regulation, Neoplastic - drug effects | Chromones - pharmacology | Anticarcinogenic Agents - pharmacology | Hydroxamic Acids - pharmacology | Phytoestrogens - pharmacology | Prostatic Neoplasms - drug therapy | PTEN Phosphohydrolase - genetics | Tumor Suppressor Proteins - metabolism | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | PTEN Phosphohydrolase - metabolism | Azacitidine - analogs & derivatives | Down-Regulation - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Histones - drug effects | Gene Expression Regulation - drug effects | Up-Regulation - drug effects | Azacitidine - pharmacology | Acetylation - drug effects | Methylation - drug effects | Genistein - pharmacology | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Histones - metabolism | Forkhead Box Protein O3 | Sirtuins - metabolism | NF-kappa B - drug effects | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 03/2016, Volume 76, Issue 6, pp. 1494 - 1505
Journal Article
Cancer, ISSN 0008-543X, 10/2011, Volume 117, Issue 19, pp. 4424 - 4438
Journal Article
Journal Article
Oncology Reports, ISSN 1021-335X, 4/2015, Volume 33, Issue 4, pp. 1976 - 1984
There has been increasing evidence that numerous bioactive dietary agents can hamper the process of carcino-genesis by targeting epigenetic alterations... 
DNMT3B | dietary agents | reactivation | HDAC1 | epigenetic | EGCG | Dietary agents | DNMT3β | Reactivation | Epigenetic | TEA POLYPHENOL | METHYLATION | GREEN TEA | LUNG-CANCER | OVEREXPRESSION | IN-VITRO | RETINOIC ACID | ONCOLOGY | EPIGENETIC REGULATION | HUMAN-MELANOMA | DNA (Cytosine-5-)-Methyltransferases - physiology | Humans | Uterine Cervical Neoplasms - pathology | DNA (Cytosine-5-)-Methyltransferases - antagonists & inhibitors | Chromatin Assembly and Disassembly - drug effects | Genes, Tumor Suppressor - drug effects | RNA, Messenger - biosynthesis | Tumor Suppressor Proteins - genetics | Enzyme Induction - drug effects | Female | Epigenesis, Genetic - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Catechin - pharmacology | Neoplasm Proteins - genetics | Anticarcinogenic Agents - pharmacology | Histone Deacetylase 1 - genetics | DNA (Cytosine-5-)-Methyltransferases - biosynthesis | Neoplasm Proteins - biosynthesis | Models, Molecular | Histone Deacetylase 1 - biosynthesis | Uterine Cervical Neoplasms - genetics | DNA (Cytosine-5-)-Methyltransferases - genetics | RNA, Neoplasm - biosynthesis | Histone Deacetylase Inhibitors - pharmacology | Protein Conformation | Catechin - analogs & derivatives | Molecular Docking Simulation | HeLa Cells | Histone Deacetylases - physiology | Tumor Suppressor Proteins - biosynthesis | DNA Methylation - drug effects | Pharmacology, Experimental | Oncology, Experimental | Development and progression | Tumor suppressor genes | Drug targeting | Genetic aspects | Research | Health aspects | Cervical cancer | Cancer | Studies | Proteins | Enzymes | Cell cycle | DNA methylation | Polyphenols | Epigenetics | Ligands | Gene expression | Kinases | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 10/2016, Volume 117, Issue 10, pp. 2302 - 2314
Journal Article
Journal Article
Journal Article
Journal Article
Oncogene, ISSN 0950-9232, 01/2009, Volume 28, Issue 2, pp. 184 - 194
RUNX3 is a tumor suppressor that is silenced in cancer following hypermethylation of its promoter. The effects of hypoxia in tumor suppressor gene (TSG)... 
Hypoxia |