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1. Genome-wide association studies
: from polymorphism to personalized medicine
by Appasani, Krishnarao, 1959- editor
2016, ISBN 9781107042766, xxxi, 391 pages, 24 unnumbered pages of plates
Genome-Wide Association Study | Genetic Testing | Genomics | Medical genetics
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2. Full Text Genetic association studies
by Cordell, Heather J and Clayton, David G
The Lancet, ISSN 0140-6736, 2005, Volume 366, Issue 9491, pp. 1121 - 1131
We review the rationale behind and discuss methods of design and analysis of genetic association studies. There are similarities between genetic association... 
Genetics, Population | Genetic Predisposition to Disease - genetics | Phenotype | Epistasis, Genetic | Gene Frequency | Humans | Genotype | Genetic Linkage | Linkage Disequilibrium | Polymorphism, Genetic | Linkage (Genetics) | Environmental impact analysis | Research | Index Medicus | Abridged Index Medicus
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3. Analysis of complex disease association studies
: a practical guide
by Zeggini, Eleftheria and Morris, Andrew Paul
2011, 1st ed., ISBN 012375142X, viii, 331, [11] p. of col. plates
According to the National Institute of Health, a genome-wide association study is defined as any study of genetic variation across the entire human genome that... 
Genetic disorders | Variation | Human genetics | Diseases | Pre-clinical Medicine: Basic Sciences
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4. Full Text Genomewide Association Studies and Human Disease
by Hardy, John and Singleton, Andrew
The New England Journal of Medicine, ISSN 0028-4793, 04/2009, Volume 360, Issue 17, pp. 1759 - 1768
Genomewide association studies have uncovered many genetic variants that confer susceptibility to disease. This article describes the genomewide association... 
MEDICINE, GENERAL & INTERNAL | CHOLESTEROL | SUSCEPTIBILITY | GENE-EXPRESSION | FACTOR-H POLYMORPHISM | MACULAR DEGENERATION | RISK | WIDE ASSOCIATION | LOCUS | DROSOPHILA-PINK1 | PARKINSONS-DISEASE | Disease - etiology | Genetic Variation | Gene Expression | Genetic Predisposition to Disease | Disease - genetics | Humans | Environment | Mutation | Genome-Wide Association Study - methods | Type 2 diabetes | Genetic aspects | Research | Human genome | Genetic variation | Rheumatoid arthritis | Index Medicus | Abridged Index Medicus
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5. Full Text Genomewide Association Study of Leprosy
by Zhang, Fu-Ren and Zhang, Chi and Zhang, Lin and Zhang, Lian-Hua and Zhang, Xue-Jun and Zhang, Zheng and Huang, Wei and Chen, Shu-Min and Sun, Yi-Ping and Sun, Liang-Dan and Liu, Rui-Yu and Liu, Yu-Qiang and Liu, Jin-Xian and Liu, Hua-Xu and Liu, Hong and Liu, Jian-Jun and Li, Yong-Ping and Li, Jin-Yong and Li, Yi and Cui, Yong and Yan, Wei-Guo and Yan, Xiao-Xiao and Yang, Ning-Han and Yang, Sen and Yang, Hai-Tao and Rong-De Yang and Chu, Tong-Sheng and Han, Jian-Wen and Yu, Gong-Qi and Yu, Jing-Ping and Yu, Yong-Xiang and Quan, Cheng and Shi, Ben-Qing and Cheng, Yi-Lin and Cheng, Hui and Wang, Kui-Jun and Wang, De-Min and Wang, Xiao-Dong and Wang, Chang-Yuan and Wang, Ying and Wang, Qiang and Lin, Yan and Zheng, Hou-Feng and Fu, Xi-An and Zuo, Xian-Bo and Long, Heng and Tian, Hong-Qing and Zhou, Fu-Sheng and Lu, Wen-Sheng and He, Su-Min and Du, Wen-Li and Shen, Min and Jin, Qi-Yi and Low, Hui-Qi and Erwin, Tantoso and Zhao, Xin and Jiao, Yue-Lin and Mao, Li-Guo and Yin, Gang and Jiang, Zhen-Xia and Hu, Zong-Hou and Gong, Cui-Hua and Wei, Shi-Yu and Wei, Dong and Cao, Hong-Zhong and Cao, Wei-Kun and Hibberd, Martin L
The New England Journal of Medicine, ISSN 0028-4793, 12/2009, Volume 361, Issue 27, pp. 2609 - 2618
Little is known about genetic susceptibility to infectious disease. This study implicates variation in genes encoding molecules in the NOD2 (nucleotide-binding... 
IMMUNITY | MEDICINE, GENERAL & INTERNAL | MYCOBACTERIA | INFLAMMATORY-BOWEL-DISEASE | CROHNS-DISEASE | GENETICS | SUSCEPTIBILITY | GENES | HLA | Genetic Predisposition to Disease | Genome-Wide Association Study | Mycobacterium leprae | Oligonucleotide Array Sequence Analysis | Signal Transduction | Humans | Middle Aged | Genotype | Male | Nod2 Signaling Adaptor Protein - genetics | Gene Regulatory Networks | Leprosy, Paucibacillary - genetics | Case-Control Studies | Leprosy, Multibacillary - genetics | Female | Aged | Polymorphism, Single Nucleotide | Leprosy | Minority & ethnic groups | Developing countries--LDCs | Parkinsons disease | Index Medicus | Abridged Index Medicus
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6. Full Text Integrative approaches for large-scale transcriptome-wide association studies
by Gusev, A and Ko, A and Shi, H and Bhatia, G and Chung, W and Penninx, B.W.J.H and Jansen, R and de Geus, E.J.C and Boomsma, D.I and Wright, F.A and Sullivan, P.F and Nikkola, E and Alvarez, M and Civelek, M and Lusis, A.J and Lehtimäki, T and Raitoharju, E and Kähönen, M and Seppälä, I and Raitakari, O.T and Kuusisto, J and Laakso, M and Price, A.L and Pajukanta, P and Pasaniuc, B
Nature Genetics, ISSN 1061-4036, 2016, Volume 48, Issue 3, pp. 245 - 252
Many genetic variants influence complex traits by modulating gene expression, thus altering the abundance of one or multiple proteins. Here we introduce a... 
HUMAN HEIGHT | PARTITIONING HERITABILITY | STATISTICS | GENETICS & HEREDITY | GENE-EXPRESSION | BODY-MASS INDEX | YOUNG FINNS | MENDELIAN RANDOMIZATION | COMPLEX TRAITS | REGULATORY VARIATION | CARDIOVASCULAR RISK | Genetic Predisposition to Disease | Genome-Wide Association Study | Phenotype | Animals | Gene Expression Regulation - genetics | Humans | Genotype | Mice | Transcriptome - genetics | Obesity - genetics | Obesity - pathology | Quantitative Trait Loci - genetics | Genome-wide association studies | Genetic research | Research | Gene expression | Identification and classification | Methods | Studies | Genotype & phenotype | Lipids | Software | Genomes | Estimates | Index Medicus
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7. Full Text Genome-Wide Association Study
by Gutierrez, AP and Yanez, JM and Fukui, S and Swift, B and Davidson, WS
PLOS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3
Early sexual maturation is considered a serious drawback for Atlantic salmon aquaculture as it retards growth, increases production times and affects flesh... 
QUANTITATIVE TRAIT LOCI | BODY-WEIGHT | RAINBOW-TROUT | GENETIC-IMPROVEMENT | MULTIDISCIPLINARY SCIENCES | QTL | COHO SALMON | MATURITY | CHARR SALVELINUS-ALPINUS | TROUT ONCORHYNCHUS-MYKISS | SNP ARRAY
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8. Full Text Efficiency and power in genetic association studies
by Daly, Mark J and de Bakker, Paul I W and Pe'er, Itsik and Yelensky, Roman and Gabriel, Stacey B and Altshuler, David
Nature Genetics, ISSN 1061-4036, 11/2005, Volume 37, Issue 11, pp. 1217 - 1223
We investigated selection and analysis of tag SNPs for genome-wide association studies by specifically examining the relationship between investment in... 
GENOTYPE DATA | HAPLOTYPE DIVERSITY | TESTS | UNRELATED INDIVIDUALS | GENETICS & HEREDITY | LINKAGE-DISEQUILIBRIUM | TAGGING SNPS | SELECTION | TAG SNPS | SINGLE-NUCLEOTIDE POLYMORPHISMS | GENOME-WIDE ASSOCIATION | Haplotypes - genetics | Genetic Predisposition to Disease | Reference Standards | Algorithms | Computer Simulation | Genetic Markers - genetics | Humans | Linkage Disequilibrium - genetics | Polymorphism, Single Nucleotide - genetics | Chromosome Mapping | Models, Genetic | Case-Control Studies | Genetic variation | Physiological aspects | Research | Nucleotide sequencing | Single nucleotide polymorphisms | Identification and classification | Health aspects | Index Medicus
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9. Full Text Searching for missing heritability: Designing rare variant association studies
by Or Zuk and Stephen F. Schaffner and Kaitlin Samocha and Ron Do and Eliana Hechter and Sekar Kathiresan and Mark J. Daly and Benjamin M. Neale and Shamil R. Sunyaev and Eric S. Lander
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 01/2014, Volume 111, Issue 4, pp. E455 - E464
Genetic studies have revealed thousands of loci predisposing to hundreds of human diseases and traits, revealing important biological pathways and defining... 
POPULATION | CONTRIBUTE | ALLELES | mapping disease genes | LOW-FREQUENCY | MULTIDISCIPLINARY SCIENCES | statistical genetics | LOCI | power analysis | GENES | SEQUENCE | MUTATIONS | SPECTRUM | SELECTION | Genetic Variation | Genetic Predisposition to Disease | Genome-Wide Association Study | Mutation | Gene Frequency | Humans | Genetics | Hypotheses | Genes | Analysis | Index Medicus | Biological Sciences | PNAS Plus
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10. GxE interactions in genome-wide association studies
by Conti, David V
2016, Statistical genetics
Bayesian statistical decision theory | Genome-Wide Association Study | methods | Statistical methods | Gene-Environment Interaction | Physiological effect | Genotype-environment interaction | Tobacco Use Disorder | Bayes Theorem | Genetics | Polymorphism, Single Nucleotide | Genetic aspects | metabolism | Nicotine | Smoking
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11. Full Text Predicting type 2 diabetes based on polymorphisms from genome-wide association studies A population-based study
by Hoek, Mandy and Dehghan, Abbas and Witteman, Jacqueline and Tikka-Kleemola, Päivi and Uitterlinden, Ané and Oostra, Ben and Hofman, Albert and Sijbrands, Eric and Janssens, Cécile
Diabetes, ISSN 0012-1797, 11/2008, Volume 57, Issue 11, pp. 3122 - 3128
textabstractOBJECTIVE-Prediction of type 2 diabetes based on genetic testing might improve identification of high-risk subjects. Genome-wide association (GWA)... 
DIAGNOSIS | RISK LOCI | IMPACT | REPLICATION | VARIANTS | GENES | ENDOCRINOLOGY & METABOLISM | CLASSIFICATION | COMPLEX DISEASES | ROTTERDAM | MELLITUS | RNA-Binding Proteins - genetics | Prospective Studies | Zinc Transporter 8 | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Alpha-Ketoglutarate-Dependent Dioxygenase FTO | Cyclin-Dependent Kinase 5 - genetics | Diabetes Mellitus, Type 2 - ethnology | Cyclin-Dependent Kinase Inhibitor p15 - genetics | Cation Transport Proteins - genetics | Neoplasm Proteins - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Membrane Proteins - genetics | Risk Factors | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Transcription Factor 7-Like 2 Protein | Polymorphism, Genetic | Proteins - genetics | ADAMTS9 Protein | tRNA Methyltransferases | Aged | ADAM Proteins - genetics | Genome, Human | TCF Transcription Factors - genetics | Type 2 diabetes | Usage | Genetic aspects | Diagnosis | Health aspects | Genetic polymorphisms | Index Medicus | Abridged Index Medicus | Genetics
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