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Nature (London), ISSN 1476-4687, 2017, Volume 546, Issue 7658, pp. 431 - 435
...). Resistance can result from secondary mutations(3,4), but in other cases there is no clear genetic cause, raising the possibility of non-genetic rare cell variability(5-11... 
METASTATIC MELANOMA | BRAF INHIBITOR | SUBPOPULATIONS | CHROMATIN | MULTIDISCIPLINARY SCIENCES | SINGLE MAMMALIAN-CELLS | STATE | MECHANISMS | MUTATIONS | VEMURAFENIB | PLASTICITY | Transcription, Genetic - drug effects | Humans | Male | Transcription Factor AP-1 - metabolism | DNA-Binding Proteins - metabolism | Melanoma - genetics | Female | Indoles - pharmacology | Epigenesis, Genetic - drug effects | Gene Expression Regulation, Neoplastic - drug effects | SOXE Transcription Factors - deficiency | Single-Cell Analysis | Cellular Reprogramming - genetics | ErbB Receptors - metabolism | In Situ Hybridization, Fluorescence | Nuclear Proteins - metabolism | Signal Transduction - genetics | Melanoma - pathology | Sulfonamides - pharmacology | Cellular Reprogramming - drug effects | Transcription Factors - metabolism | Xenograft Model Antitumor Assays | Genetic Markers - drug effects | Vemurafenib | Drug Resistance, Neoplasm - genetics | Animals | Signal Transduction - drug effects | Genetic Markers - genetics | Cell Line, Tumor | Oncogene Protein p65(gag-jun) - metabolism | Drug Resistance, Neoplasm - drug effects | SOXE Transcription Factors - genetics | Antimitotic agents | Cell interaction | Dosage and administration | Antineoplastic agents | Drug resistance | Observations | Health aspects | Subpopulations | Transcription factors | Substance abuse treatment | Variability | Activator protein 1 | Melanoma | Genomes | Kinases | Gene expression | Sox10 protein | Signal transduction | Signaling | Converting | Population | Mutation | Differentiation | Deoxyribonucleic acid--DNA | Cancer
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 2010, Volume 463, Issue 7283, pp. 913 - 918
.... To examine the consequences of gene expression variability in multicellular organisms, we studied intestinal specification in the nematode Caenorhabditis elegans in which wild-type cell fate... 
SINGLE-CELL | ELT-2 | CAENORHABDITIS-ELEGANS | GATA-FACTOR | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | ENDODERM | POP-1 | C-ELEGANS | DIFFERENTIATION | SKN-1 | Chromatin - metabolism | Intestinal Mucosa - metabolism | Caenorhabditis elegans Proteins - metabolism | Gene Expression Regulation, Developmental - genetics | RNA, Messenger - analysis | Chromatin Assembly and Disassembly - genetics | Intestines - embryology | DNA-Binding Proteins - metabolism | Cell Differentiation - genetics | GATA Transcription Factors - metabolism | Stochastic Processes | RNA, Helminth - genetics | Cell Lineage - genetics | Gene Regulatory Networks - genetics | Caenorhabditis elegans - genetics | RNA, Messenger - genetics | In Situ Hybridization, Fluorescence | Penetrance | Transcription Factors - genetics | Caenorhabditis elegans - embryology | DNA-Binding Proteins - genetics | GATA Transcription Factors - genetics | Transcription Factors - metabolism | Animals | RNA, Helminth - analysis | Models, Genetic | Caenorhabditis elegans Proteins - genetics | Chromatin - genetics | Intestines - cytology | Caenorhabditis elegans | Genetic aspects | Research | Gene mutations | Genetic variation | Proteins | Genetics | Gene expression | Embryos | Environmental conditions | Mutations | Networks | Genes | Nematodes | Organisms | Invariants
Journal Article
Nature (London), ISSN 1476-4687, 2013, Volume 502, Issue 7469, pp. 59 - 64
Journal Article
Journal Article
Brain (London, England : 1878), ISSN 1460-2156, 2016, Volume 139, Issue 5, pp. 1551 - 1567
Journal Article