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PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, pp. e51056 - e51056
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, pp. e67686 - e67686
MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression by targeted repression of transcription and translation. In this study we show that... 
BIOMARKERS | CELLS | METASTASIS | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | MODEL | MESENCHYMAL TRANSITION | Carcinoma, Transitional Cell - mortality | Cell Proliferation | Luciferases - metabolism | Urinary Bladder Neoplasms - diagnosis | Homeodomain Proteins - metabolism | Humans | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | Urinary Bladder - pathology | Epithelial-Mesenchymal Transition - genetics | Luciferases - genetics | Urinary Bladder Neoplasms - genetics | Urinary Bladder Neoplasms - pathology | Biomarkers, Tumor - metabolism | Cell Cycle Checkpoints - genetics | Real-Time Polymerase Chain Reaction | Genes, Reporter | Carcinoma, Transitional Cell - genetics | Urinary Bladder Neoplasms - mortality | Signal Transduction | Urinary Bladder - metabolism | Carcinoma, Transitional Cell - diagnosis | Kaplan-Meier Estimate | Transcription Factors - genetics | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Carcinoma, Transitional Cell - pathology | Cell Line, Tumor | Protein Binding | Biomarkers, Tumor - genetics | MicroRNAs - genetics | Cell Movement | Zinc Finger E-box-Binding Homeobox 1 | MicroRNA | Physiological aspects | Development and progression | Tumor suppressor genes | Genetic aspects | Research | Bladder cancer | Cell proliferation | Flow cytometry | Mesenchyme | Veterans | Bladder | Fluorescence | Metastasis | Kinases | Tissues | Medical diagnosis | Urology | Urinary bladder | Cell cycle | Bioindicators | Inhibition | MiRNA | Tumor cell lines | Gene expression | Ribonucleic acid--RNA | Gene silencing | Overexpression | MicroRNAs | Medical prognosis | Cell lines | Biomarkers | Diagnostic systems | Prostate cancer | Cell migration | Cancer | Apoptosis | Tumors | Index Medicus | RNA | Ribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, pp. e115870 - e115870
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2012, Volume 7, Issue 6, pp. e39469 - e39469
Growing evidence indicates that Rab GTPases, key regulators of intracellular transport in eukaryotic cells, play an important role in cancer. We analysed the... 
BREAST-CANCER | UROTHELIAL DIFFERENTIATION | HEPATOCELLULAR-CARCINOMA | EXCHANGE FACTOR | UROPLAKIN-IB | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | GROWTH-FACTOR RECEPTOR-3 | PPAR-GAMMA | MUTATIONS | EXPRESSION | Cell Proliferation | Urothelium - metabolism | Humans | Gene Expression Regulation, Neoplastic | Databases, Genetic | rab GTP-Binding Proteins - genetics | Gene Expression Profiling | Receptor, Fibroblast Growth Factor, Type 3 - metabolism | Protein Interaction Maps | Cell Differentiation - genetics | Protein Isoforms - metabolism | Urinary Bladder Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Urinary Bladder Neoplasms - metabolism | rab GTP-Binding Proteins - metabolism | Cell Line | Receptor, Fibroblast Growth Factor, Type 3 - genetics | Signal Transduction | Protein Interaction Mapping | Algorithms | Models, Biological | Protein Binding | Mutation | Cluster Analysis | Protein Isoforms - genetics | Proteins | Analysis | Genes | Genetic aspects | Genetic transcription | G proteins | Bladder cancer | Tumors | Cancer | Cluster analysis | Regulators | Deregulation | Transcription | Pathogenesis | Bladder | Subgroups | Liver cancer | Pathways | Urinary bladder | Rodents | Clusters | Fibroblasts | Growth factors | Urine | Invasiveness | Markers | Muscles | Cell differentiation | Studies | DNA microarrays | Urothelium | Fibroblast growth factor receptors | Index Medicus
Journal Article
Current Opinion in Oncology, ISSN 1040-8746, 03/2017, Volume 29, Issue 3, pp. 184 - 195
PURPOSE OF REVIEWT-cell checkpoint blockade has become a dynamic immunotherapy for bladder cancer. In 2016, atezolizumab, an immune checkpoint inhibitor,... 
neoantigen | urothelial carcinoma | bladder cancer | mutational burden | immune checkpoint | combination immunotherapy | biomarker | CTLA-4 BLOCKADE | MULTICENTER | BCG | METASTATIC UROTHELIAL CARCINOMA | CISPLATIN PLUS IPILIMUMAB | OPEN-LABEL | ANTI-PD-L1 ANTIBODY | ONCOLOGY | CLINICAL ACTIVITY | EXPRESSION | AVELUMAB MSB0010718C | GENITOURINARY SYSTEM | Edited by Arif Hussain
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, pp. e84311 - e84311
Current genome-wide microRNA (miRNA) expression signature analysis using deep sequencing technologies can drive the discovery of novel cancer pathways... 
CARCINOMA-CELLS | APOPTOSIS | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | MIR-133A | ONCOGENIC FUNCTION | T24 CELLS | CELL-CYCLE ARREST | TUMORIGENICITY | IDENTIFICATION | TUMOR SUPPRESSORS | Cell Proliferation | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Molecular Sequence Data | Male | MicroRNAs - metabolism | Gene Expression Profiling | Urinary Bladder - pathology | Neoplasm Proteins - metabolism | RNA, Messenger - metabolism | Transfection | Urinary Bladder Neoplasms - genetics | Base Sequence | Urinary Bladder Neoplasms - pathology | Aged, 80 and over | Female | High-Throughput Nucleotide Sequencing - methods | Neoplasm Proteins - genetics | Epithelium - pathology | Epithelium - metabolism | Urinary Bladder - metabolism | Neoplasm Invasiveness | Molecular Sequence Annotation | RNA, Messenger - genetics | Signal Transduction - genetics | Down-Regulation - genetics | Cell Line, Tumor | Aged | MicroRNAs - genetics | Cell Movement | Genomes | MicroRNA | Gene expression | Analysis | Genes | Genomics | Cell proliferation | Bladder | Kinases | Urology | Western blotting | Metastases | Gene sequencing | Pathways | Urinary bladder | Cell cycle | Clusters | Tumorigenesis | Bioinformatics | University graduates | MiRNA | Breast cancer | Ribonucleic acid--RNA | Bladder cancer | Suppressors | Studies | Signaling | MicroRNAs | Cell lines | Aberration | Signature analysis | Cell migration | Cancer | Apoptosis | Tumors | Index Medicus | RNA | Ribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 4, pp. e18135 - e18135
Background: Current diagnosis and treatment of urinary bladder cancer (BC) has shown great progress with the utilization of microarrays. Purpose: Our goal was... 
YIN YANG 1 | HEPATOCELLULAR-CARCINOMA | CDNA MICROARRAYS | TRANSITIONAL-CELL CARCINOMA | CHROMOSOMAL DOMAINS | MULTIDISCIPLINARY SCIENCES | HYDROGEN-PEROXIDE | EXPERIMENTAL-DESIGN | NF-KAPPA-B | COMPUTATIONAL ANALYSIS | PITUITARY-ADENOMAS | Immunohistochemistry | Oligonucleotide Array Sequence Analysis - methods | Humans | Gene Expression Profiling - methods | Male | Chromosome Mapping | Case-Control Studies | Transcription Factors - metabolism | Urinary Bladder Neoplasms - genetics | Aged | Biomarkers, Tumor - genetics | Principal Component Analysis | Urinary Bladder Neoplasms - metabolism | Cluster Analysis | Care and treatment | Analysis | Genes | Bone morphogenetic proteins | Genomes | Cellular signal transduction | Genetic aspects | DNA binding proteins | Genetic transcription | Bladder cancer | Cancer | Transcription factors | Laboratories | Lung cancer | Bladder | Cell interactions | Tissues | Cancer therapies | Urology | Ovarian cancer | Liver cancer | Urinary bladder | Clusters | RNA processing | Chromosomes | Bone morphogenetic protein 4 | Vector quantization | Histology | YY1 protein | Gene expression | Clustering | Metabolism | Ribonucleic acid--RNA | Chromosome 1 | Virology | Studies | Disease prevention | Chemotherapy | Hospitals | DNA microarrays | Biopsy | Data sets | Adenoviruses | Chromosome 21 | Ligands | Transduction | Tumors | Apoptosis | Index Medicus | RNA | Ribonucleic acid
Journal Article
Journal Article