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2016, 1st ed. 2016, Advances in experimental medicine and biology, ISBN 9781493935079, Volume 895, xvi, 263 pages
This comprehensive volume explores human genetic engineering its pre-clinical and clinical applications, current developments, and as treatment for hereditary... 
Gene therapy | Genetic engineering | Human genetics | Human Genetics | Biomedicine
Book
2016, ISBN 1107172160, xi, 440 pages
Would you change your genes if you could? As we confront the 'industrial revolution of the genome', the recent discoveries of Crispr-Cas9 technologies are... 
Genomes | Gene targeting | Medicine: General Issues
Book
2016, ISBN 9780198766827, xii, 352 pages, 2 pages of unnumbered plates
Book
Cell, ISSN 0092-8674, 09/2016, Volume 167, Issue 1, pp. 233 - 247.e17
Journal Article
Nature, ISSN 0028-0836, 11/2017, Volume 551, Issue 7681, pp. 464 - 471
The spontaneous deamination of cytosine is a major source of transitions from C·G to T·A base pairs, which account for half of known pathogenic point mutations... 
Directed evolution | Fracture mechanics | Disease | Biological evolution | Genomes | Drug resistance | Experiments | Guanine | Efficiency | Bacteria | Cleavage | Evolution | Cytosine | Nuclease | Deoxyribonucleic acid--DNA | Transfer RNA | CRISPR | Protein engineering | Enzymes | Adenosine | Base pairs | Adenine | Ductile-brittle transition | Adenosine deaminase | Ribonucleic acid--RNA | Studies | Antibiotics | Deamination | Mutation | Index Medicus
Journal Article
eLife, ISSN 2050-084X, 01/2013, Volume 2013, Issue 2, pp. e00471 - e00471
Type II CRISPR immune systems in bacteria use a dual RNA-guided DNA endonuclease, Cas9, to cleave foreign DNA at specific sites. We show here that Cas9... 
IMMUNITY | SYSTEMS | BACTERIA | ARCHAEA | BIOLOGY | NUCLEASE | RNA Editing | Humans | Clustered Regularly Interspaced Short Palindromic Repeats | RNA - genetics | Proteins | CRISPR | RNA editing | Nucleotide sequence | DNA damage | Genomes | RNA polymerase | Endonuclease | Localization | Ribonucleic acid--RNA | DNA repair | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
SCIENCE, ISSN 0036-8075, 09/2015, Volume 349, Issue 6252, pp. 1115 - 1120
Adenosine-to-inosine (A-to-I) editing is a highly prevalent posttranscriptional modification of RNA, mediated by ADAR (adenosine deaminase acting on RNA)... 
APOPTOSIS | INTERFERON | ADENOSINE-DEAMINASE | GENE | MULTIDISCIPLINARY SCIENCES | MOUSE | SITES | MUTATIONS | IDENTIFICATION | ENZYME ADAR1 | GENOME
Journal Article
Journal Article
Critical Reviews in Plant Sciences, ISSN 0735-2689, 01/2017, Volume 36, Issue 1, pp. 1 - 23