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Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 483 - 493
Activation-induced cytidine deaminase (AID) is a B-cell-specific enzyme that targets immunoglobulin genes to initiate class switch recombination and somatic... 
CHROMOSOMAL TRANSLOCATIONS | SUPER-ENHANCERS | INDUCED CYTIDINE DEAMINASE | DNA | MULTIDISCIPLINARY SCIENCES | CHRONIC LYMPHOCYTIC-LEUKEMIA | CLASS-SWITCH RECOMBINATION | TARGETING BTK | AID | HYPERMUTATION | SEQUENCING REVEALS | Isoquinolines - adverse effects | Class I Phosphatidylinositol 3-Kinases - metabolism | Humans | Lymphoma, Mantle-Cell - pathology | Phosphatidylinositol 3-Kinases - metabolism | Leukemia, Lymphocytic, Chronic, B-Cell - genetics | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Translocation, Genetic - drug effects | Isoquinolines - pharmacology | Antineoplastic Agents - adverse effects | Genomic Instability - drug effects | Female | Antineoplastic Agents - pharmacology | Purines - adverse effects | B-Lymphocytes - pathology | Immunoglobulin Class Switching - drug effects | Somatic Hypermutation, Immunoglobulin - drug effects | Lymphoma, Mantle-Cell - genetics | B-Lymphocytes - metabolism | Quinazolinones - pharmacology | Pyrazoles - adverse effects | Pyrazoles - pharmacology | Enzyme Inhibitors - adverse effects | B-Lymphocytes - enzymology | Purines - pharmacology | Enzyme Inhibitors - pharmacology | Pyrimidines - pharmacology | Class I Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Leukemia, Lymphocytic, Chronic, B-Cell - pathology | B-Lymphocytes - drug effects | Animals | Cytidine Deaminase - metabolism | Pyrimidines - adverse effects | Cell Line, Tumor | Mice | Immunoglobulin Heavy Chains - genetics | Quinazolinones - adverse effects | Recombination, Genetic - drug effects | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2009, Volume 106, Issue 21, pp. 8671 - 8676
Journal Article
Journal Article
Nature, ISSN 0028-0836, 08/2018, Volume 560, Issue 7718, pp. 325 - 330
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 08/2017, Volume 13, Issue 8, pp. 888 - 894
Journal Article
Nature, ISSN 0028-0836, 07/2018, Volume 559, Issue 7713, pp. 279 - 284
Accurate replication of DNA requires stringent regulation to ensure genome integrity. In human cells, thousands of origins of replication are coordinately... 
POLY(ADP-RIBOSE) POLYMERASE | REPAIR | PCNA | P21(WAF1/CIP1) | CELL NUCLEAR ANTIGEN | REPRESSION | MULTIDISCIPLINARY SCIENCES | PARP | INHIBITORS | CANCER | DAMAGE | DNA Damage - drug effects | DNA Replication - drug effects | Humans | Tumor Suppressor Protein p53 - metabolism | Poly (ADP-Ribose) Polymerase-1 - metabolism | Piperazines - pharmacology | Chromosome Structures - drug effects | Poly (ADP-Ribose) Polymerase-1 - antagonists & inhibitors | Phthalazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors - pharmacology | DNA Replication - physiology | Time Factors | Cell Line, Tumor | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Genomic Instability - drug effects | Genetic research | DNA replication | Research | DNA damage | Oncology, Experimental | Cancer | Analysis | Genomics | DNA | Development and progression | Genomes | Tumor proteins | DNA repair | Cells | Phosphorylation | p53 Protein | Poly(ADP-ribose) | Kinases | ADP | Modulators | Replication forks | Genomic instability | Damage tolerance | Proteins | Ribose | Proliferating cell nuclear antigen | Cell cycle | Inhibition | Speed control | Lesions | Stalling | Deoxyribonucleic acid--DNA | Elongation | ADP-ribosylation | Stresses | Stability | Poly(ADP-ribose) polymerase | Gene expression | Velocity | Suppressors | Stress | Polymerase | DNA biosynthesis | Cyclin-dependent kinase inhibitor p21 | Replication origins | S phase | Replication | Instability | Control stability | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 05/2013, Volume 121, Issue 20, pp. 4175 - 4183
Journal Article
Nature Structural & Molecular Biology, ISSN 1545-9993, 05/2009, Volume 16, Issue 5, pp. 492 - 498
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 08/2012, Volume 109, Issue 33, pp. E2205 - E2214
Journal Article
Plant Physiology, ISSN 0032-0889, 10/2013, Volume 163, Issue 2, pp. 867 - 881
The plastid genome is highly conserved among plant species, suggesting that alterations of its structure would have dramatic impacts on plant fitness.... 
Oxidative stress | Leaves | Reactive oxygen species | Phenotypes | Chloroplasts | Genes | Genomes | SIGNALING AND RESPONSE | Plants | Plastids | Chlorophylls | VARIEGATION MUTANTS | RESPONSES | OXIDATIVE STRESS | GENE | CHLOROPLAST DEVELOPMENT | PHOTOSYSTEM-II | SINGLET OXYGEN | LIGHT STRESS | TOPOISOMERASE-IV | DNA-POLYMERASES | PLANT SCIENCES | Cell Death - radiation effects | Genome, Plastid - genetics | Inheritance Patterns - drug effects | Reactive Oxygen Species - metabolism | Cellular Reprogramming - radiation effects | Arabidopsis - growth & development | Adaptation, Physiological - drug effects | Stress, Physiological - radiation effects | Arabidopsis Proteins - metabolism | Arabidopsis - radiation effects | Cell Nucleus - metabolism | Photosynthesis - genetics | Adaptation, Physiological - genetics | Cell Nucleus - radiation effects | Light | Plastids - drug effects | Genomic Instability - drug effects | Inheritance Patterns - genetics | Plastids - genetics | Stress, Physiological - drug effects | Cell Death - drug effects | Signal Transduction - radiation effects | Cellular Reprogramming - genetics | DNA, Plant - genetics | Inheritance Patterns - radiation effects | Photosynthesis - radiation effects | Genomic Instability - radiation effects | Arabidopsis Proteins - genetics | Stress, Physiological - genetics | Arabidopsis - ultrastructure | Ciprofloxacin - pharmacology | Signal Transduction - genetics | Adaptation, Physiological - radiation effects | Mutation - genetics | Arabidopsis - genetics | Cellular Reprogramming - drug effects | Phenotype | Signal Transduction - drug effects | Photosynthesis - drug effects | Plastids - ultrastructure | Gene Rearrangement - genetics | Plastids - radiation effects | Cell Nucleus - drug effects | Arabidopsis thaliana | Physiological aspects | Genetic aspects | Cellular signal transduction | Research | Gene expression | Index Medicus
Journal Article